Gene Information

Name : lysS (JTY_3664)
Accession : YP_002646704.1
Strain : Mycobacterium bovis Tokyo 172
Genome accession: NC_012207
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 4017699 - 4019216 bp
Length : 1518 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGAGTGCCGCTGACACAGCAGAAGACCTTCCTGAGCAGTTCCGGATTCGCCGGGACAAGCGCGCTCGCTTGCTGGCCCA
GGGGCGCGATCCCTATCCCGTCGCGGTGCCGCGCACTCACACGTTGGCCGAGGTTCGCGCCGCCCACCCTGACTTGCCGA
TCGATACCGCGACCGAAGACATCGTCGGCGTCGCGGGCCGAGTGATCTTTGCGCGCAACTCGGGAAAGCTATGCTTTGCG
ACACTTCAGGACGGCGATGGTACCCAGCTGCAAGTGATGATCAGCCTCGACAAGGTCGGCCAGGCTGCTCTCGACGCATG
GAAAGCCGATGTCGACCTGGGCGACATCGTCTACGTGCATGGCGCGGTGATCAGTTCGCGCCGCGGCGAGCTGTCCGTCC
TGGCGGATTGCTGGCGGATCGCCGCCAAGTCGCTGCGGCCGCTTCCCGTCGCGCACAAAGAGATGAGTGAAGAGTCGCGG
GTTCGTCAGCGCTATGTTGACCTCATAGTTCGACCGGAAGCGCGCGCGGTGGCTCGACTACGGATCGCCGTCGTCCGCGC
GATCCGGACGGCGCTTCAACGTCGTGGGTTCCTGGAAGTCGAGACGCCCGTCTTGCAGACGTTAGCCGGTGGTGCGGCGG
CCCGTCCGTTCGCCACTCATTCCAATGCCCTAGACATCGATCTGTACCTGCGGATCGCGCCGGAACTGTTCCTCAAGCGC
TGCATCGTGGGTGGTTTCGACAAGGTCTTCGAACTTAATCGAGTGTTCCGAAACGAAGGAGCCGATTCCACGCATTCTCC
GGAATTCTCCATGCTGGAGACCTACCAGACCTACGGAACCTATGACGATTCGGCAGTCGTCACCCGGGAGCTTATTCAAG
AGGTGGCCGATGAGGCGATCGGAACCAGACAACTGCCGTTGCCCGACGGCAGTGTCTATGACATCGACGGAGAATGGGCG
ACTATACAAATGTACCCGTCGCTGTCTGTGGCGCTCGGTGAAGAGATCACACCGCAGACGACGGTCGATCGCTTACGTGG
GATCGCCGATAGCCTTGGCCTGGAGAAAGACCCAGCGATTCATGACAACCGTGGCTTCGGCCACGGCAAACTCATCGAGG
AACTCTGGGAGCGCACAGTGGGCAAGAGCTTGAGCGCACCCACATTTGTCAAGGATTTTCCGGTTCAGACAACGCCTTTG
ACCCGTCAGCACCGCAGTATCCCCGGCGTAACCGAGAAGTGGGACCTCTATCTGCGCGGAATCGAACTTGCCACCGGCTA
CTCGGAATTAAGCGACCCGGTAGTCCAGCGGGAGAGATTCGCCGACCAGGCCCGTGCCGCGGCCGCTGGCGATGACGAAG
CGATGGTGCTTGACGAGGATTTTCTGGCCGCTCTGGAGTACGGCATGCCACCGTGCACCGGAACCGGAATGGGTATCGAT
CGGTTGTTGATGTCTTTGACTGGGTTGTCAATTAGGGAGACAGTTTTGTTCCCGATTGTTCGACCACACTCCAACTGA

Protein sequence :
MSAADTAEDLPEQFRIRRDKRARLLAQGRDPYPVAVPRTHTLAEVRAAHPDLPIDTATEDIVGVAGRVIFARNSGKLCFA
TLQDGDGTQLQVMISLDKVGQAALDAWKADVDLGDIVYVHGAVISSRRGELSVLADCWRIAAKSLRPLPVAHKEMSEESR
VRQRYVDLIVRPEARAVARLRIAVVRAIRTALQRRGFLEVETPVLQTLAGGAAARPFATHSNALDIDLYLRIAPELFLKR
CIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTRELIQEVADEAIGTRQLPLPDGSVYDIDGEWA
TIQMYPSLSVALGEEITPQTTVDRLRGIADSLGLEKDPAIHDNRGFGHGKLIEELWERTVGKSLSAPTFVKDFPVQTTPL
TRQHRSIPGVTEKWDLYLRGIELATGYSELSDPVVQRERFADQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGID
RLLMSLTGLSIRETVLFPIVRPHSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-142 61