Gene Information

Name : topB (SPC_2434)
Accession : YP_002637984.1
Strain : Salmonella enterica RKS4594
Genome accession: NC_012125
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 2486380 - 2488329 bp
Length : 1950 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGGGCGCGCCATTGCGGATGTGCTGCCAAAACCGCACCGTAAAGGCGA
TGGTTTTATTGAGTGCGGAAACGGGCAGGTCGTCACCTGGTGTATTGGTCATTTGCTGGAACAGGCGCAGCCGGATGCGT
ATGACAGCCGTTATGCGCGCTGGAATCTGGCTGACCTGCCTATCGTGCCGGAAAAATGGCAGCTTCAGCCTCGTCCTTCC
GTCACCAAACAGCTCAATGTGATTAAGCGCTTTTTGCATCAAGCCGGTGAAATTATTCACGCTGGCGACCCGGATCGCGA
AGGGCAGCTTCTGGTTGATGAAGTGCTGGATTATCTCCAGCTTCCTGCCGAAAAGCGCCAACAGGTGCGGCGTTGTCTGA
TAAACGACCTTAACCCGCAGGCGGTCGAGCGTGCTATCGACAGGCTGCGAGCGAACAGCGACTTCGTGCCGCTGTGCGTC
TCCGCGCTGGCGCGAGCGCGAGCGGACTGGCTGTATGGCATTAATATGACCCGCGCTTACACGATCCTGGGCCGTAATGC
TGGCTATCAGGGCGTGTTATCCGTGGGACGCGTACAGACGCCGGTACTGGGGCTGGTGGTGCGGCGAGACGAAGAGATTG
AGAACTTCGTCGCCAAAGACTTCTTTGAAGTGAAGGCGCACATCGTTACGCCTGCCGACGAGCGTTTTACCGCTATCTGG
CAGCCGAGCGAGGCGTGCGAACCTTATCAGGATGAAGAAGGGCGCTTGCTGCATCGTCCGCTGGCGGAGCATGTGGTGAA
CCGAATCAACGGTCAGCCCGCGCTGGTAACCAGTTATAATGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGC
TCTCGACGCTACAGATTGAAGCCGCTAAACGCTTTGGCCTGAGCGCGCAAAACGTGCTTGATATTTGTCAGAAGCTATAT
GAAACCCACAAACTGATTACCTATCCGCGTTCCGACTGCCGTTATCTGCCGGAAGAACACTTTGCCGGACGGCAGGCGGT
CATGAACGCGATTAGCGTCCACGCCCCGGATTTACTGCCGCAGCCTGTGGTTAATCCTGATACGCGCAATCGCTGCTGGG
ATGACAAAAAAGTGGATGCGCACCACGCGATTATCCCGACGGCGCGCAGTTCTTCTGTCCATCTGACGGAAAACGAAGCG
AAAGTGTACACCCTGATTGCGCGTCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTTCGTAAATGCGTTATTGAACT
GGAAATCGCCAAAGGGAAATTTGTCGCCAAAGCGCGTTTTCTGGCGGAGGCCGGTTGGCGGACGTTACTGGGCAGTAAAG
AGCGCGACGAGGAAAACGACGGTACGCCGCTGCCGGTTGTCGCCAAAGGTGATGAGTTGCTGTGTGAAAAGGGGGAAGTG
GTCGAGCGCCAAACCCAGCCGCCGCGTCATTTCACTGATGCGACATTGCTTTCCGCGATGACCGGAATTGCCCGCTTCGT
GCAGGATAAAGATCTGAAAAAGATCCTGCGCGCGACCGATGGGCTGGGGACGGAAGCCACGCGCGCCGGGATTATCGAGC
TGCTGTTCAAACGTAGCTTTCTGACCAAAAAAGGGCGCTACATTCATTCTACCGATGCTGGCAAAGCGTTAATACATTCG
CTGCCGGAAATGGCGGCCCGTCCAGATATGACCGCGCACTGGGAATCTGTTTTGACGCAAATCAGCGAAAAGCAGTGCCG
TTACCAGGATTTCATGCAACCGCTGGTCGGCACGTTATATCAGCTGATCGAGCAGGCTAAGCGCACGCCGGTGAAGCGCT
TCAGAGGGATAGTCGCGCCAGGCGGTGGAGACAAGAAAAAGAGCGCGCCGCGTAAGCGAGCGGGCAAAAAAAGCCCGCCT
GCTAAGGAGACAGGCCGTCAGACCGAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEA
KVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHS
LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPP
AKETGRQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-103 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-110 41