Gene Information

Name : ssrA (SPC_2337)
Accession : YP_002637895.1
Strain : Salmonella enterica RKS4594
Genome accession: NC_012125
Putative virulence/resistance : Virulence
Product : two-component sensor kinase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0642
EC number : -
Position : 2386539 - 2389301 bp
Length : 2763 bp
Strand : +
Note : -

DNA sequence :
ATGAATTTGCTCAATCTCAAGAATACGCTGCAAACATCTTTAGTAATCAGGCTAACTTTTTTATTTTTATTAACAACAAT
AATTATTTGGCTGCTATCTGTGCTTACCGCAGCTTATATATCAATGGTTCAGAAACGGCAGCATATAATAGAGGATTTAT
CCGTTCTATCCGAGATGAATATTGTACTAAGCAATCAACGGTTTGAAGAAGCTGAACGTGACGCTAAAAATTTAATGTAT
CAATGCTCATTAGCGACTGAGATTCATCATAACGATATTTTCCCTGAGGTGAGCCGGCATCTATCTGTCGGTCCTTCAAA
TTGCACGCCGACGCTAAACGGAGAGAAGCACCGTCTCTTTCTGCAGTCCTCTGATATCGATGAAAAAAGCTTTCGTCGCG
ATAGTTTTATTCTTAATCATAAAAATGAGATTTCGTTATTATCTACTGATAACCCTTCAGATTATTCAACTCTACAGCCT
TTAACGCGAAAAAGCTTTCCTTTATACCCAACCCATGCCGGGTTTTACTGGAGTGAACCAGAATACATAAACGGCAAAGG
ATGGCACGCCTCCGTTGCGGTTGCCGATCAGCAAGGCGTATTTTTTGGGGTGACGGTTAAACTTCCCGATCTCATTACTA
AGAGCCACCTACCATTAGATGATAGTATTCGAGTATGGCTGGATCAAAACAACCACTTATTGCCGTTTTCATACATCCCG
CAAAAAATACGTACACAGTTAGAAAATGTAACGCTGCATGATGGATGGCAGCAAATTCCCGGATTTCTGATATTACGCAC
AACCTTGCATGGCCCCGGATGGAGTCTGGTTACGCTGTACCCATACGGTAATCTACATAATCGCATCTTAAAAATTATCC
TTCAACAAATCCCCTTTACATTAACAGCATTGGTGTTGATGACGTCGGCTTTTTGCTGGTTACTACATCGCTCACTGGCC
AAACCGTTATGGCGTTTTGTCGATGTCATTAATAAAACCGCAACTGCACCGCTGAGCACACGTTTACCAGCACAACGACT
GGATGAATTAGATAGTATTGCCGGTGCTTTTAATCAACTGCTTGATACTCTACAAGTCCAATACGACAATCTGGAAAACA
AAGTCGCAGAGCGCACCCAGGCGCTAAATGAAGCAAAAAAACGCGCTGAGCGAGCTAACAAACGTAAAAGCATTCATCTT
ACGGTAATAAGTCATGAGTTACGTACTCCGATGAATGGCGTACTCGGTGCGATTGAATTATTACAAACCACCCCTTTAAA
CATAGAGCAGCAAGGATTAGCTGATACCGCCAGAAATTGTACACTGTCTTTGTTAGCTATTATTAATAATCTGCTGGATT
TTTCACGCATCGAGTCTGGTCATTTCACATTACATATGGAAGAAACAGCGTTACTGCCGTTACTGGACCAGGCAATGCAA
ACCATCCAGGGGCCAGCGCAAAGCAAAAAACTGTCATTACGTACTTTTGTCGGTCAACATGTCCCTCTCTATTTTCATAC
CGACAGTATCCGTTTACGGCAAATTTTGGTTAATTTACTCGGGAATGCGGTAAAATTTACCGAAACCGGAGGGATACGTC
TGACGGTCAAGCGTCATGAGGAACAATTAATATTTCTGGTTAGCGATAGCGGTAAAGGGATTGAAATACAGGAGCAGTCT
CAAATCTTTACTGCTTTTTATCAAGCAGACACAAATTCGCAAGGTACAGGAATTGGACTGACTATTGCGTCAAGCCTGGC
TAAAATGATGGGCGGTAATCTGACACTAAAAAGTGTCCCCGGGGTTGGAACCTGTGTCTCGCTAGTATTACCCTTACAAG
AATACCAGCCGCCTCAACCAATTAAAGGGACACTATCAGCGCCGTTCTGCCTGCATCGGCAACTGGCTTGCTGGGGAATA
CGCGGCGAACCACCGCACCAGCAAAATGCGCTTCTCAACGCAGAGCTTTTGTATTTCCCCGGAAAACTCTACGACCTGGC
GCAACAGTTAATATTGTGTACACCAAATATACCAGTAATAAATAATTTGTTACCTCCCTGGCAGTTGCAGATTCTTTTGG
TTGATGATGCCGATATTAATCGGGATATCATCAGCAAAATGCTTGTCAGCCTGGGACAACACGTCACTATTGCCGCCAGT
AGTAACGAGGCTCTGACTTTATCACAACAGCAGCGATTCGATTTAGTACTGATTGACATTAGAATGCCAGAAATAGATGG
TATTGAATGTGTACAATTATGGCATGATGAGCCGAATAATTTAGATCCTGACTGCATGTTTGTGGCGCTATCCGCTAGCG
TAGCGACAGAAGATATTCATCGTTGTAAAAAAAATGGGATTCATCATTACATTACCAAACCAGTGACATTGGCTACCTTA
GCTCGCTATATCAGTATTGCCGCAGAATACCAACTTTTACGAAATATAGAGCTACAGGAGCAGGATCCGAGTCGCTGCTC
AGCGCTACTGGCGACAGATGATATGGTCATTAATAGCAAGATTTTCCAATCACTGGACCTCTTGCTGGCTGATATTGAAA
ATGCCGTATCGGCTGGACAAAAAATCGATCAGTTAATTCACACATTAAAAGGCTGTTTAGGTCAAATAGGGCAGACTGAA
TTGGTATGCTATGTCATAGACATTGAGAATCGCGTAAAAATGGGGAAAATCATCGCGCTGGAGGAACTAACCGACTTACG
CCAGAAAATACGTATGCTCTTCAAAAACTACACCATTACTTAA

Protein sequence :
MNLLNLKNTLQTSLVIRLTFLFLLTTIIIWLLSVLTAAYISMVQKRQHIIEDLSVLSEMNIVLSNQRFEEAERDAKNLMY
QCSLATEIHHNDIFPEVSRHLSVGPSNCTPTLNGEKHRLFLQSSDIDEKSFRRDSFILNHKNEISLLSTDNPSDYSTLQP
LTRKSFPLYPTHAGFYWSEPEYINGKGWHASVAVADQQGVFFGVTVKLPDLITKSHLPLDDSIRVWLDQNNHLLPFSYIP
QKIRTQLENVTLHDGWQQIPGFLILRTTLHGPGWSLVTLYPYGNLHNRILKIILQQIPFTLTALVLMTSAFCWLLHRSLA
KPLWRFVDVINKTATAPLSTRLPAQRLDELDSIAGAFNQLLDTLQVQYDNLENKVAERTQALNEAKKRAERANKRKSIHL
TVISHELRTPMNGVLGAIELLQTTPLNIEQQGLADTARNCTLSLLAIINNLLDFSRIESGHFTLHMEETALLPLLDQAMQ
TIQGPAQSKKLSLRTFVGQHVPLYFHTDSIRLRQILVNLLGNAVKFTETGGIRLTVKRHEEQLIFLVSDSGKGIEIQEQS
QIFTAFYQADTNSQGTGIGLTIASSLAKMMGGNLTLKSVPGVGTCVSLVLPLQEYQPPQPIKGTLSAPFCLHRQLACWGI
RGEPPHQQNALLNAELLYFPGKLYDLAQQLILCTPNIPVINNLLPPWQLQILLVDDADINRDIISKMLVSLGQHVTIAAS
SNEALTLSQQQRFDLVLIDIRMPEIDGIECVQLWHDEPNNLDPDCMFVALSASVATEDIHRCKKNGIHHYITKPVTLATL
ARYISIAAEYQLLRNIELQEQDPSRCSALLATDDMVINSKIFQSLDLLLADIENAVSAGQKIDQLIHTLKGCLGQIGQTE
LVCYVIDIENRVKMGKIIALEELTDLRQKIRMLFKNYTIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssrA NP_456136.1 putative two-component sensor kinase Virulence SPI-2 Protein 0.0 99
ssrA NP_805063.1 two-component sensor kinase Virulence SPI-2 Protein 0.0 99
ssrA NP_460357.1 sensor kinase Virulence SPI-2 Protein 0.0 99
ssrA YP_216400.1 secretion system regulator:sensor component Virulence SPI-2 Protein 0.0 99
spiR AAC44299.1 SpiR Virulence SPI-2 Protein 0.0 99
YPO0256 YP_002345336.1 two-component sensor/regulator Not tested Not named Protein 4e-163 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ssrA YP_002637895.1 two-component sensor kinase VFG0493 Protein 0.0 99