Gene Information

Name : ssaV (SPC_2315)
Accession : YP_002637873.1
Strain : Salmonella enterica RKS4594
Genome accession: NC_012125
Putative virulence/resistance : Virulence
Product : secretion system apparatus protein SsaV
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 2370497 - 2372473 bp
Length : 1977 bp
Strand : -
Note : with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system

DNA sequence :
ATGGTTCTGGCGACGGTGTTATTAATCGCTATTGTGATGATGCTGTTACCTTTACCGACCTGGATGGTTGATATCCTGAT
TACTATCAACCTTATGTTTTCAGTGATCCTGCTCTTAATTGCTATTTATCTTAGTGACCCTCTCGATTTATCGGTATTTC
CGTCTTTATTACTTATTACTACATTATATCGTTTGTCACTCACAATCAGCACATCACGGCTGGTACTGTTACAACATAAT
GCCGGTAATATTGTGGATGCTTTCGGTAAGTTTGTCGTAGGAGGAAATCTCACCGTTGGGTTGGTCGTATTTACCATCAT
TACTATCGTGCAGTTTATTGTCATTACAAAAGGTATCGAGAGGGTGGCGGAAGTTAGCGCACGTTTCTCGCTTGATGGGA
TGCCAGGCAAACAAATGAGTATCGATGGCGATTTGCGTGCCGGAGTTATCGATGCAGACCATGCCCGTACATTAAGACAG
CACGTCCAGCAGGAAAGCCGCTTTCTCGGTGCGATGGACGGTGCGATGAAATTTGTTAAAGGCGATACGATTGCCGGTAT
TATTGTTGTTCTGGTGAACATTATCGGCGGTATCATTATCGCTATCGTGCAATATGATATGTCGATGAGTGAGGCTGTTC
ACACTTATAGCGTACTGTCAATCGGAGATGGTTTATGTGGGCAAATTCCATCGCTGCTGATTTCCCTTAGCGCGGGAATT
ATTGTCACCCGTGTTCCGGGTGAGAAACGCCAGAACCTGGCGACAGAGTTGAGTTCTCAAATTGCCAGACAACCTCAGTC
GCTCATATTAACCGCTGTGGTTTTAATGCTCCTCGCTTTAATTCCTGGCTTTCCTTTTATCACTCTCGCTTTCTTTTCAG
CGTTGTTAGCATTGCCAATTATCCTCATTCGCCGCAAAAAGTCTGTGGTTTCCGCAAATGGCGTCGAAGCACCGGAAAAA
GATAGTATGGTTCCCGGCGCATGTCCTCTAATCTTACGTCTTACCCCGACGTTACATTCTGCCGACCTGATTCGTGATAT
TGACGCCATGAGATGGTTTTTATTTGAGGATACCGGCGTTCCTCTCCCTGAGGTGAACATTGAGGTTTTGCCTGAACCCA
CCGAAAAATTGACGGTACTGCTATATCAGGAACCCGTATTTAGTTTATCTATTCCCGCCCAGGCGGATTATTTATTGATA
GGCGCGGACGCTAGTGTGGTGGGTGACAGCCAGACGTTACCGAACGGGATGGGGCAGATCTGTTGGCTTACAAAAGACAT
GGCCCATAAGGCGCAAGGTTTTGGACTGGACGTTTTCGCGGGCAGCCAACGTATCTCTGCCTTATTAAAATGTGTCCTGC
TTCGCCATATGGGAGAGTTTATTGGTGTTCAGGAAACGCGTTATCTAATGAATGCGATGGAAAAAAACTACTCTGAGCTG
GTGAAAGAGCTTCAGCGCCAGTTACCCATTAATAAAATCGCTGAAACTTTGCAACGGCTTGTATCAGAGCGGGTTTCTAT
TAGAGATTTACGTCTTATTTTCGGCACCTTAATTGATTGGGCGCCACGTGAAAAAGATGTCCTGATGTTGACAGAATATG
TCCGTATCGCGCTTCGCCGTCATATTCTGCGTCGTCTTAATCCGGAAGGAAAACCGCTGCCGATTTTGCGGATCGGCGAA
GGTATTGAGAACCTCGTGCGTGAATCCATTCGCCAGACGGCAATGGGGACCTATACTGCGCTGTCGTCTCGTCATAAGAC
GCAGATCCTGCAACTTATCGAGCAGGCGCTGAAGCAGTCAGCCAAATTATTCATTGTCACTTCTGTCGACACCCGACGTT
TCTTGCGAAAAATTACAGAAGCCACCTTGTTCGACGTACCGATTTTGTCATGGCAGGAATTAGGAGAGGAGAGCCTTATA
CAAGTGGTAGAAAGTATTGACCTTAGCGAAGAGGAGTTGGCGGACAATGAAGAATGA

Protein sequence :
MVLATVLLIAIVMMLLPLPTWMVDILITINLMFSVILLLIAIYLSDPLDLSVFPSLLLITTLYRLSLTISTSRLVLLQHN
AGNIVDAFGKFVVGGNLTVGLVVFTIITIVQFIVITKGIERVAEVSARFSLDGMPGKQMSIDGDLRAGVIDADHARTLRQ
HVQQESRFLGAMDGAMKFVKGDTIAGIIVVLVNIIGGIIIAIVQYDMSMSEAVHTYSVLSIGDGLCGQIPSLLISLSAGI
IVTRVPGEKRQNLATELSSQIARQPQSLILTAVVLMLLALIPGFPFITLAFFSALLALPIILIRRKKSVVSANGVEAPEK
DSMVPGACPLILRLTPTLHSADLIRDIDAMRWFLFEDTGVPLPEVNIEVLPEPTEKLTVLLYQEPVFSLSIPAQADYLLI
GADASVVGDSQTLPNGMGQICWLTKDMAHKAQGFGLDVFAGSQRISALLKCVLLRHMGEFIGVQETRYLMNAMEKNYSEL
VKELQRQLPINKIAETLQRLVSERVSIRDLRLIFGTLIDWAPREKDVLMLTEYVRIALRRHILRRLNPEGKPLPILRIGE
GIENLVRESIRQTAMGTYTALSSRHKTQILQLIEQALKQSAKLFIVTSVDTRRFLRKITEATLFDVPILSWQELGEESLI
QVVESIDLSEEELADNEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssaV YP_216422.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 0.0 100
ssaV CAA70536.1 secretion system apparatus Virulence SPI-2 Protein 0.0 99
ssaV NP_456114.1 putative type III secretion protein Virulence SPI-2 Protein 0.0 99
ssaV NP_805085.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 0.0 99
ssaV NP_460379.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 0.0 99
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 6e-137 59
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 2e-109 49
escV AAC38382.1 EscV Virulence LEE Protein 1e-110 49
unnamed AAL06368.1 EscV Virulence LEE Protein 4e-108 48
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 3e-110 48
escV CAI43875.1 EscV protein Virulence LEE Protein 1e-110 48
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 3e-110 48
escV YP_003223476.1 translocator EscV Virulence LEE Protein 2e-110 48
escV CAC81861.1 EscV protein Virulence LEE II Protein 4e-110 48
escV AAC31514.1 L0035 Virulence LEE Protein 3e-110 48
escV ACU09459.1 EscV protein Virulence LEE Protein 3e-110 48
escV AAK26714.1 EscV Virulence LEE Protein 2e-110 48
escV AAL57541.1 EscV Virulence LEE Protein 2e-110 48
escV NP_290269.1 hypothetical protein Virulence LEE Protein 3e-110 48
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 9e-102 48
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 2e-101 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ssaV YP_002637873.1 secretion system apparatus protein SsaV VFG0514 Protein 0.0 99
ssaV YP_002637873.1 secretion system apparatus protein SsaV VFG0729 Protein 8e-111 49
ssaV YP_002637873.1 secretion system apparatus protein SsaV VFG0813 Protein 1e-110 48
ssaV YP_002637873.1 secretion system apparatus protein SsaV VFG0064 Protein 7e-84 43
ssaV YP_002637873.1 secretion system apparatus protein SsaV VFG0384 Protein 2e-81 41