Gene Information

Name : wzc (SPC_1605)
Accession : YP_002637194.1
Strain : Salmonella enterica RKS4594
Genome accession: NC_012125
Putative virulence/resistance : Unknown
Product : tyrosine kinase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3206
EC number : -
Position : 1679681 - 1681840 bp
Length : 2160 bp
Strand : +
Note : Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide)

DNA sequence :
ATGACAGAAAAAGTAAAACAATCTGCGGCGGTTACGGGTAGCGATGAAATCGATATCGGGCGTCTGGTCGGAACGGTGAT
TGAAGCGCGTTGGTGGGTGTTGGGGACGACGGCCATATTTGCGCTGTGCGCGGTAATTTATACGTTCTTCGCCACACCCA
TCTATAGCGCCGATGCGCTGGTGCAGATTGAACAAAACGCCGGTAATTCGCTGGTACAGGATATCAACAGCGCATTAGCG
AATAAGCCGCCGGCTTCCGATGCGGAAATTCAGCTCATTCGATCGCGCCTGGTGCTGGGGAAGACCGTTGACGATCTGGA
TCTGGATATTGCCGTCACCAAAAACACCTTTCCGCTCTTTGGCGCCGGGTGGGAACGGCTGATGGGACGTCACAATGAAA
TGGTGAAAGTCACGACATTCACCCGACCAGAGACGATGAGCGGACAGATCTTCACCCTCAAAGTGCTGGGCGACAAACGT
TATCAGTTGGTTAGCGACGGCGGATTTAGCGCGCAGGGCGTTGTGGGCCAGCCACTCAATAAAGACGGCGTGACGATGCG
GGTAGAGGCGATTGACGCCCGTCCTGATACAGAATTTACGGTGAGTAAATTCTCAACGCTTGGCATGATTAATAACCTGC
AAAATAACCTCACCGTAACGGAAACCGGCAAAGATACCGGCGTTCTGAGCCTGACGTTCACGGGAGAGGATCGCGACCAG
ATCCGCGACATTCTCAACAGTATTACCCGTAACTATCTGCAACAGGATATTGCGCGAAAATCTGAAGAGGCGGGGAAGAG
CCTGGCGTTTCTGGCAAAACAACTGCCGGAAGTCCGCAGCCGTCTGGATGTGGCGGAAAACAAGCTAAACGCTTTCCGCC
AGGATAAAGACTCGGTGGATTTACCGCTGGAGGCGAAGGCGGTGCTCGATTCGATGGTTAATATCGACGCCCAGTTGAAT
GAGTTGACGTTTAAAGAGGCGGAAATTTCCAAGCTCTTTACCAAAGCGCATCCGGCTTACCGCACCCTGCTGGAAAAACG
TAAAGCGCTGGAAGATGAAAAAGCCAAACTGAACGGGCGGGTGACGGCAATGCCGAAAACCCAGCAGGAGATTGTGCGTT
TGACCCGTGATGTGGAGTCCGGCCAGCAGGTTTATATGCAACTGCTTAATAAACAGCAGGAGCTGAAAATCACCGAAGCC
AGCACCGTTGGCGACGTGCGCATCGTTGACCCGGCGATTACCCAGCCGGGCGTGCTGAAGCCGAAAAAGGCGTTGATTAT
TCTCGGCAGCATTATTCTGGGATTAATGTTATCGATTGTCGGCGTGCTGCTGCGCTCGCTGTTTAATCGCGGTATCGAAA
GCCCGCAGGCGCTGGAGGAGCACGGGATCAGCGTCTATGCCAGTATTCCGCTGTCGGAATGGCAAAAAGCGCGCGATAGC
GTCAAAACCATTAAAGGAATTAAGCGTTACAAGCAGAGCCAACTGCTGGCGGTGGGCAATCCGACCGATCTGGCGATTGA
GGCGATTCGCAGCCTGCGCACCAGCCTGCATTTCGCCATGATGCAGGCGCAAAATAATGTACTCATGCTCACAGGCGTCA
GCTCCTCTATCGGCAAAACCTTTGTTTGCGCCAACCTGGCGGCCGTCATCAGCCAGACGCATAAACGGGTATTACTGATC
GACTGCGATATGCGCAAAGGCTACACCCATGAACTGCTCGGCACCAATAACGTGGACGGCTTATCTGACATTCTGGCGGG
CAAAGGCGAGATAGCCTCCTGCGCGAAACCCACGGCGATCGCTAATTTTGATCTTATTCCGCGCGGTCAGGTACCGCCTA
ATCCATCGGAATTGCTGATGAGCGAGCGCTTCGGCGAGCTGATCGCCTGGGCAAGCAGCCGCTACGATCTGGTATTAATC
GACACGCCGCCGATTCTGGCCGTGACGGACGCCGCGATTGTGGGTCGTCACGTCGGGACGACGCTGATGGTGGCGCGTTA
TGCCGTCAACACCTTAAAAGAGGTGGAAACCAGTCTGAGCCGTTTTGACCAGAATGGCATTCAGGTCAAAGGCGTCATTC
TCAACTCCATTTTCCGCCGGGCGACGGGCTACCAGGATTATGGCTATTACGAATATGAATACCAGTCAGATTCCAAATAA

Protein sequence :
MTEKVKQSAAVTGSDEIDIGRLVGTVIEARWWVLGTTAIFALCAVIYTFFATPIYSADALVQIEQNAGNSLVQDINSALA
NKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVTKNTFPLFGAGWERLMGRHNEMVKVTTFTRPETMSGQIFTLKVLGDKR
YQLVSDGGFSAQGVVGQPLNKDGVTMRVEAIDARPDTEFTVSKFSTLGMINNLQNNLTVTETGKDTGVLSLTFTGEDRDQ
IRDILNSITRNYLQQDIARKSEEAGKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLN
ELTFKEAEISKLFTKAHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEA
STVGDVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQALEEHGISVYASIPLSEWQKARDS
VKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMLTGVSSSIGKTFVCANLAAVISQTHKRVLLI
DCDMRKGYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERFGELIAWASSRYDLVLI
DTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFDQNGIQVKGVILNSIFRRATGYQDYGYYEYEYQSDSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf41 AAO18066.1 Orf41 Not tested TTSS locus Protein 1e-158 48