Gene Information

Name : cadB (SPC_1092)
Accession : YP_002636699.1
Strain : Salmonella enterica RKS4594
Genome accession: NC_012125
Putative virulence/resistance : Virulence
Product : lysine/cadaverine antiporter
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0531
EC number : -
Position : 1135472 - 1136809 bp
Length : 1338 bp
Strand : -
Note : antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein

DNA sequence :
ATGAACATGAGTTCTGTCAAAAAGATCGGGCTATTTGCCTGTACTGGCGTCGTTGCCGGTAATATGATGGGGAGCGGGAT
TGCATTATTACCCGCCAACCTTGCCAGTATTGGTGGCATTGCCATCTGGGGCTGGGTAATTTCTATTATTGGGGCAATGT
CGCTGGCTTATGTTTATGCGAGGCTGGCAACCAAAAACCCTCAACAGGGTGGCCCTATCGCTTATGCTGGGGAAATATCT
CCGGCGTTTGGTTTCCAAACCGGCGTTCTTTATTATCACGCAAACTGGATTGGTAACTTAGCCATCGGCATTACCGCTGT
TTCTTATCTTTCTACGTTCTTCCCGGCATTAAATAATCCAATACCGGCAGGTATTGCCTGTATTGCTATCGTCTGGCTGT
TCACCTTTATTAATATGCTGGGCGGGGCCTGGGTCAGCCGTTTGACAACGATTGGCCTATTCCTGGTGCTGATCCCGGTA
GTCTTGACCGCAGTCGCCGGCTGGCATTGGTTCGATATCGCGACCTATCACGCGAACTGGAACACGTCTACGACGACCGA
CTCTCACGCCATTGTTAAAAGTATTCTGCTCTGCCTGTGGGCGTTCGTTGGCGTTGAGTCTGCCGCCGTCAGCACCGGCA
TGGTGAAAAACCCGAAACGCACCGTACCGCTGGCAACCATGCTGGGTACCGCGCTGGCAGGCATCATCTATATCGCCGCG
ACTCAGGTTATCGCCGGGATGTTCCCAGCTTCCGTTATGGCCTCTTCCGGCGCGCCGTTCGCTATCAGTACCTCCACGAT
TCTGGGTGGCTGGGCTGCGCCGCTGGTTTCCGCCTTTACCGCTTTCGCCTGCCTGACGTCTCTGGGCTCCTGGATGATGC
TGGTCGGCCAGGCTGGGGTTCGCGCCGCCAACGACGGCAACTTCCCGAAAATTTACGGTGAAATGGATAAAAACGGTATT
CCGAAAAAAGGTCTGCTGTTGGCTGCGGTGAAAATGACGGCGCTGATGATTCTGATCACCATCATGAACTCCAGCGGCGG
TAAAGCGTCCGACCTGTTCGGCGAACTGACCGGGATTGCCGTACTGCTTACCATGCTGCCGTACTTCTACTCCTGTGTTG
ACCTGATTCGCTTCGAAGGGTTCAACATCCGTAACTCGGTAAGCCTGATTTGTTCTGTACTGGGCTGCGCATTTTGCTTC
ATCGCACTGATGGGCGCCAGCTCCTTCGAACTCTCCGGCACCTTTATCGTCAGTCTGATCATCCTGATGTTCTACGGTCG
CAAAATGCACCAGCGCCAGAACAACGACAGCGACAACAATACGGCTGAAGCGCTTTAA

Protein sequence :
MNMSSVKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWVISIIGAMSLAYVYARLATKNPQQGGPIAYAGEIS
PAFGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPALNNPIPAGIACIAIVWLFTFINMLGGAWVSRLTTIGLFLVLIPV
VLTAVAGWHWFDIATYHANWNTSTTTDSHAIVKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLGTALAGIIYIAA
TQVIAGMFPASVMASSGAPFAISTSTILGGWAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKIYGEMDKNGI
PKKGLLLAAVKMTALMILITIMNSSGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGFNIRNSVSLICSVLGCAFCF
IALMGASSFELSGTFIVSLIILMFYGRKMHQRQNNDSDNNTAEAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadB AAL67382.1 cadaverine/lysine antiporter Not tested PAI II CFT073 Protein 0.0 90
cadB NP_756989.1 lysine/cadaverine antiporter Not tested PAI II CFT073 Protein 0.0 90
unnamed CAD66196.1 putative lysin/cadaverin transporter Virulence PAI III 536 Protein 5e-144 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadB YP_002636699.1 lysine/cadaverine antiporter VFG1671 Protein 3e-144 68