Gene Information

Name : metC (Sca_0087)
Accession : YP_002633186.1
Strain : Staphylococcus carnosus TM300
Genome accession: NC_012121
Putative virulence/resistance : Resistance
Product : putative Cys/Met metabolism pyridoxal-5'-phosphate dependent enzyme
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 85775 - 86920 bp
Length : 1146 bp
Strand : +
Note : (P56069) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS) (O-succinylhomoserine (Thiol)-lyase),InterPro: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; Hypothetical protein

DNA sequence :
ATGAAAAAGAAAACACAAATGGTACATGGCGGACATACTACTGACGATTACACTGGTGCGGTAACAACACCTATTTATCA
AACAAGCACTTATTTACAAGATGATATCGGTGACTTGCGTGAAGGATATGAATATTCACGAAGCGGCAACCCTACACGTA
CAGCTTTAGAAAGCACAATTGCTGACTTAGAAGGTGCACGTTTTGGTTTCGCATTCGGTTCAGGTGTTGCAGCAATTTCA
GCAGTCGTAATGCTATTAGATAAAGGTGATCACATTGTAGTGAATTCAGATGTGTACGGCGGTACATTCCGTGTGTTGAC
TAAAGTGTTTAAACGTTTAGGTATCGATGCTGATTTCGTTGATACAACACATACTGAAAACATTGAAAGTGCGATTAAAC
CAGAAACTAAAATGTTATTTATCGAAACACCATCAAATCCATTATTACGTATAACTGATATCCAAGCTTCAGCTGATATC
GCACGTAAACACAATTTGATTTCAGTTGTAGATAATACATTCATGTCACCTTACTTCCAAAATCCATTAGCTTTAGGTGC
TGATATCGTATTGCATTCAGCTTCTAAATATATTGGCGGACACAGTGACGTTATTGCTGGATTAGTTGCGACTGATAATG
AAGAGTTAGCTGAACGTATTGGTTTCATTCAAAATTCAACAGGCGGCGTTTTAGGACCGCAAGACAGTTATTTATTAATT
CGTGGTATTAAAACATTAGGCTTACGTATGGAACAAGTAAGCAGCAATGCGGTTGCAGTGACTGAAATGTTATCAGAACA
CCCTAATGTTGAAGCGGTTTACCACCCAAGCTTGAAAGATCATTTAAACCACGATGTACAAGAACGTCAAGCATCAGGTC
ATACTGGAGTTATCTCATTTGTAGTTAAAGATGTGGATGCTGCTAAAGCTGTTATTCGTGAAACAGAATATTTCACATTA
GCAGAAAGCTTAGGTGCGGTTGAAAGTTTAATCTCTGTTCCAGCACTTATGACACATGCATCTATTCCTAAAGATGTACG
TGAAAAAGAAGGTATCGCTGATGGATTAATCCGTTTGTCAGTAGGTATTGAAGATACAGATGATTTAGTTGCAGACTTAA
AACAAGCTCTAGATAAATTAAATTAA

Protein sequence :
MKKKTQMVHGGHTTDDYTGAVTTPIYQTSTYLQDDIGDLREGYEYSRSGNPTRTALESTIADLEGARFGFAFGSGVAAIS
AVVMLLDKGDHIVVNSDVYGGTFRVLTKVFKRLGIDADFVDTTHTENIESAIKPETKMLFIETPSNPLLRITDIQASADI
ARKHNLISVVDNTFMSPYFQNPLALGADIVLHSASKYIGGHSDVIAGLVATDNEELAERIGFIQNSTGGVLGPQDSYLLI
RGIKTLGLRMEQVSSNAVAVTEMLSEHPNVEAVYHPSLKDHLNHDVQERQASGHTGVISFVVKDVDAAKAVIRETEYFTL
AESLGAVESLISVPALMTHASIPKDVREKEGIADGLIRLSVGIEDTDDLVADLKQALDKLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-144 74
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-143 74
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-74 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_002633186.1 putative Cys/Met metabolism pyridoxal-5'-phosphate dependent enzyme BAC0207 Protein 8e-60 41