Gene Information

Name : guaA (Sca_0050)
Accession : YP_002633150.1
Strain : Staphylococcus carnosus TM300
Genome accession: NC_012121
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 50184 - 51725 bp
Length : 1542 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAAATGGCGAAAGAACAAGAAATGATTCTTGTATTAGATTTTGGTAGCCAATATAACCAATTGATAACACGTCGTAT
TCGTGAAATGGGCGTATACAGTGAATTGCATGATCACGAAATTTCTATTGAAGAAATTAAAAAGATGAATCCAAAAGGTA
TCATCTTATCTGGTGGTCCGAACTCAGTATATGAAGAAGGCTCATACACAATCGACCCTGAAATTTATAATCTAGGCGTG
CCTGTTCTTGGTATTTGCTACGGTATGCAATTAACGACTAAATTATTAGGCGGTAAAGTAGAACGTGCAAATGAAAGAGA
ATATGGTAAAGCTATCATCCATGCTAAAGCAGATGAATTATTCTTCGGATTACCTGAAGAACAAACAGTATGGATGAGCC
ATTCTGATAAAGTGATTGAAATTCCAGAAGGATTTGAATCAATTGCAGATAGTCCAAGTACGCCATATGCTGCAATTGAA
GATAAAGAGCGTCGTATTTACGGCGTTCAATTCCATCCAGAAGTACGTCATACAGAATATGGTAACGATATTTTACGTAA
TTTCGTACGCCGTATCTGTGATTGTACTGGTGAATGGACTATGGAAAACTTCATCGATTTAGAAATCGAAAAAATTCGCG
AACAAGTTGGAGACCGCAAAGTGTTATGTGCAATGAGCGGCGGTGTAGATTCATCAGTAGTTGCTGTATTATTGCATAAA
GCGATCGGTGACCAATTGACTTGTATCTTTGTTGACCATGGTTTGCTTCGTAAAGGCGAAGGCGACATGGTAATGGAACA
ATTCGGTGAAGGTTTCAACATGAACATTATCCGTGTAAATGCGAAAGACCGTTTCATGGATAAATTAAAAGGTGTTTCTG
ACCCTGAACAAAAACGTAAAATTATTGGTAACGAATTTGTTTATGTATTTGATGATGAAGCATCTAAATTAGAAGGTGTA
GACTTCCTTGCACAAGGTACGCTTTACACTGACGTTATCGAATCAGGTACAAAAACTGCACAAACAATCAAATCTCACCA
CAATGTTGGTGGATTACCTGAAGACATGCAGTTTGAATTAATCGAACCTATCAATACATTATTCAAAGATGAAGTGCGTG
CTTTAGGTATTGAATTAGGTATTCCTGAACACTTAGTTTGGAGACAACCATTCCCAGGTCCAGGACTTGGTATCCGTGTA
CTAGGTGAAATTACTGAAGAAAAATTAGAAATCGTCCGCGAATCAGATGCGATTTTACGCGAAGTGATTCGTGAAGAAGG
ATTAGAACGTGAAATTTGGCAATACTTCACAGTATTACCAGGCATGCGTTCAGTAGGTGTAATGGGTGACTATCGTACTT
ATGATTATACGATTGGTATCCGTGCCGTAACTTCTATTGATGGAATGACAAGTGACTTTGCGCGTATCGACTGGGAAGTT
TTACAAAAAATCTCAAGTCGTATTGTAAATGAAGTTGATCATGTAAACCGCGTTGTTTATGATGTAACTTCTAAGCCGCC
AAGTACAATAGAATGGGAATAA

Protein sequence :
MEMAKEQEMILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSYTIDPEIYNLGV
PVLGICYGMQLTTKLLGGKVERANEREYGKAIIHAKADELFFGLPEEQTVWMSHSDKVIEIPEGFESIADSPSTPYAAIE
DKERRIYGVQFHPEVRHTEYGNDILRNFVRRICDCTGEWTMENFIDLEIEKIREQVGDRKVLCAMSGGVDSSVVAVLLHK
AIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMDKLKGVSDPEQKRKIIGNEFVYVFDDEASKLEGV
DFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMQFELIEPINTLFKDEVRALGIELGIPEHLVWRQPFPGPGLGIRV
LGEITEEKLEIVRESDAILREVIREEGLEREIWQYFTVLPGMRSVGVMGDYRTYDYTIGIRAVTSIDGMTSDFARIDWEV
LQKISSRIVNEVDHVNRVVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 94
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 94
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 94
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-131 51