Gene Information

Name : nrdE (Sca_0379)
Accession : YP_002633478.1
Strain : Staphylococcus carnosus TM300
Genome accession: NC_012121
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 388133 - 390229 bp
Length : 2097 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGAACGAAAAGCAATATAATCATATTGAATTAAATAATGAGGTAACAAAGCGTAAAGAAGATGGCTTTTTCAGCTTAGA
AAAAGACCAAGAAGCGCTAGCGGTTTATCTTGAAGAGATTAAAGATCACACTATTTATTTCGATAGTGAAATTGAACGTT
TGCACTATCTTGTCGATAATGATTTCTATGTAGACGTATTTGCGCAATACAGCGAAGAAGACTTGAAAGAGTTAACAGAT
TTTGCACGTAGTATTCCTTTCAAATTTGCCAGCTATATGTCTGCAAGTAAATTTTTCAAAGACTATGCACTTAAAACAAA
TGATAAAAAACAATATTTAGAAGATTATTCACAACACGTAACTATCGTATCACTTTATTTAGCTGATGGTGATAAAGAAC
AAGCGCGCCAATTTATTTCATCTATGATTGAGCAGCGTTACCAACCTGCTACTCCAACATTTTTAAATGCTGGTCGTGCC
CGCCGAGGCGAACTAGTGTCATGTTTCTTATTAGAAGTAGATGATAGTTTGAATTCAATCAACTTTATCGATTCAACAGC
AAAACAGTTGAGTAAAATCGGTGGTGGTGTAGCAATCAACCTATCAAAACTTCGTGCACGCGGCGAAGCTATCAAAGGTA
TCAAAGGTGTTGCCAAAGGTGTATTACCGGTAGCTAAGTCTTTAGAAGGCGGATTCAGTTACGCAGATCAACTTGGTCAA
AGACCTGGTGCTGGTGCAGTATATTTGAATATCTTCCATTATGATGTTGAAGAATTCTTAGATACTAAAAAGGTTAATGC
TGATGAAGATATCCGTTTATCAACAATCTCTACTGGTTTAATTGTACCTGCTAAATTCTTTGAACTTGCTAAAAACGGTG
AAGACTTCTATATGTTTGCACCACATACTGTTTATAACGAATATGGTGTAACATTGGATGATATTGATTTGGATAAATAT
TACGATGATATGGTTAAAAACCCTAATATTTTAAAACATAAAAAAGATGCACGTGAAATGTTAAATACAATTGCGCAAAC
ACAATTGCAATCAGGTTATCCTTATTTAATGTTTAAAGATAATGCGAACAAAGTACATGCTAACTCTAATATCGGTCAAA
TTAAAATGAGTAACTTATGTACTGAGATTTTCCAATTACAAGAAACATCAGTTATTAATGATTACGGTATTGAAGATGAA
ATTAAACGTGATATTTCATGTAACTTAGGTTCATTAAATATTGTAAATGTAATGGAATCCGGTAAATTCAGAGATTCAGT
GCATACTGGTATGGATGCTTTAACAGTTGTAAGTGATGAAGCAAATATCCAAAATGCTCCGGGTGTGCGCAAAGCTAATA
GTGAGCTGCACTCAGTAGGTCTTGGTGTTATGAATTTGCATGGTTATCTTGCTAAAAATCAAATTGGTTATGAGTCTGAA
GAAGCAAAAGATTTTGCGAATATATTCTTTATGACAATGAACTATTATTCAATTGAACGTTCAATGCAAACTGCAAAAGA
ACGTGGCCAAGCTTATCAAGACTTTGATAAATCAGACTATGCAAGCGGAAAATATTTCGAAAAATATACGCAAGCTGACA
TTGTTCCTGAATATGAAAAAGTTAAATCTTTATTTGAAGGATTAGAAATTCCGACAGCTGAAGATTGGAAAACATTAGAA
AAAGATGTTAAAGAATATGGGTTATACCATGCATATCGCTTAGCGATTGCGCCAACTCAAAGTATTTCTTACGTTCAGAA
TGCAACAAGTTCAGTTATGCCGATTGTTGATCAAATTGAACGCCGTACTTATGGCAACTCAGAAACATTTTATCCGATGC
CATTCTTATCACCGCAAACAATGTGGTATTACAAATCAGCATTTAACACAGATCAAATGCGTTTAATTGATTTAGTAGCA
ACAATCCAACAACATGTCGATCAAGGAATTTCAACAATTCTATATGTAAATTCAGAAATATCTACACGTGAATTGTCACG
TCTATATGTTTATGCGCATCATAAAGGATTAAAATCTCTTTATTATACACGTAATAAGTTATTGAGCGTAGATGAGTGTA
CAAGCTGCGCAATTTAA

Protein sequence :
MNEKQYNHIELNNEVTKRKEDGFFSLEKDQEALAVYLEEIKDHTIYFDSEIERLHYLVDNDFYVDVFAQYSEEDLKELTD
FARSIPFKFASYMSASKFFKDYALKTNDKKQYLEDYSQHVTIVSLYLADGDKEQARQFISSMIEQRYQPATPTFLNAGRA
RRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPVAKSLEGGFSYADQLGQ
RPGAGAVYLNIFHYDVEEFLDTKKVNADEDIRLSTISTGLIVPAKFFELAKNGEDFYMFAPHTVYNEYGVTLDDIDLDKY
YDDMVKNPNILKHKKDAREMLNTIAQTQLQSGYPYLMFKDNANKVHANSNIGQIKMSNLCTEIFQLQETSVINDYGIEDE
IKRDISCNLGSLNIVNVMESGKFRDSVHTGMDALTVVSDEANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNQIGYESE
EAKDFANIFFMTMNYYSIERSMQTAKERGQAYQDFDKSDYASGKYFEKYTQADIVPEYEKVKSLFEGLEIPTAEDWKTLE
KDVKEYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNSETFYPMPFLSPQTMWYYKSAFNTDQMRLIDLVA
TIQQHVDQGISTILYVNSEISTRELSRLYVYAHHKGLKSLYYTRNKLLSVDECTSCAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 4e-134 43