Gene Information

Name : dapE (Sca_0033)
Accession : YP_002633133.1
Strain : Staphylococcus carnosus TM300
Genome accession: NC_012121
Putative virulence/resistance : Unknown
Product : succinyl-diaminopimelate desuccinylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0624
EC number : 3.5.1.18
Position : 34001 - 35167 bp
Length : 1167 bp
Strand : -
Note : dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is simi

DNA sequence :
ATGGGAAAATTAAGTTCTGAAGAAAAAGTTGAAATATTAGCAGACTTAGTAGGTATTGAATCTGTAAATGATAACGAATT
GGATGTAGCAAACTACTTACATGACTTATTCCAAAAACATCATATAGATTCTAAAATCATAAAACTTACTGATACACGCG
CTAATTTGGTAGCTGAAATAGGAAGTGGCAGTCCAGTTCTAGCCGTTTCAGGGCATATGGACGTTGTATCTCCTGGAGAT
TCTTCAAAATGGCAGACTCCGCCTTTCAAATTAACTGAAGATAGCGAAGGGCATTTACATGGGCGCGGTGCTTCAGATAT
GAAATCAGGTCTTGCTGCGTTTGTAATCAGTATGATCGAACTCCATGAACAAGGATTGCCTAAACACGGTACAGTTCGTT
TATTAGCAACAGCTGGTGAAGAAATTGAAGGACACGGCGCAAAAGCTTTTTATAAAGACGGCTATATGAATGATGTAGAT
GCGCTTGTTATCGCAGAACCTTCTAAAGATAAAATTATATATGCACACAAAGGTTCCATGGATATTCGTGTCACTTCAAA
TGGTAAATCTGTTCATAGCTCTATGCCGAGTCTAGGCTATAATGCAATTAATCCTCTCGTTGATTTTGTTAATCGTATTA
ATCAAGCTTATAATTCAATCACAGAAAGCAACGATTTATTAGGAGATTCAGTTGTCAGCGCAACAATCATCAATGGCGGT
TCTCAAGTCAATTCAATTCCGGATTATGCAGAAGCTGAATTCAATGTGAGAACGATTCCTGAAGCAGACAACGATAGTTA
TCAAAAACTTTTTGAACAAATTGCTAAAAATGTAAAAGTGGATGCACCAGACAGCTATTTAAATATCGACACTTATATGT
CTCGCCCTCCTGTCTTCACTAAAGGTGATAACCGCTTAGTTGATATTGCCCAATCATTAAGTAAAAAATACTTAGGCAAA
GAAGTTCCGAAAAAAGCTTCACCTGGAGTAACCGATGCTTCTGACTTAGTAGTAGATAAAGGAGAAGATTTCCCGTTCAT
CATGTTCGGACCTGGCGAAACAAGCCAAGCACATGTCATTGATGAATATGTAGATAAAAAAGATTATTTAAACTTTATAG
ATTTATTTGAAGACTTATTAGTAGAATACCTAGATGAAAATGAATAA

Protein sequence :
MGKLSSEEKVEILADLVGIESVNDNELDVANYLHDLFQKHHIDSKIIKLTDTRANLVAEIGSGSPVLAVSGHMDVVSPGD
SSKWQTPPFKLTEDSEGHLHGRGASDMKSGLAAFVISMIELHEQGLPKHGTVRLLATAGEEIEGHGAKAFYKDGYMNDVD
ALVIAEPSKDKIIYAHKGSMDIRVTSNGKSVHSSMPSLGYNAINPLVDFVNRINQAYNSITESNDLLGDSVVSATIINGG
SQVNSIPDYAEAEFNVRTIPEADNDSYQKLFEQIAKNVKVDAPDSYLNIDTYMSRPPVFTKGDNRLVDIAQSLSKKYLGK
EVPKKASPGVTDASDLVVDKGEDFPFIMFGPGETSQAHVIDEYVDKKDYLNFIDLFEDLLVEYLDENE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dapE CAA07459.1 succinyl-diaminopimelate desuccinylase Not tested Internalin Protein 6e-69 45
unnamed CAC20637.1 - Not tested Internalin Protein 4e-68 45