Gene Information

Name : hemC (Sca_1276)
Accession : YP_002634367.1
Strain : Staphylococcus carnosus TM300
Genome accession: NC_012121
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1283848 - 1284774 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGCGTAAGCTTGTGGTTGGTTCGCGCAGAAGTAAATTAGCATTGACGCAAAGTCGTCAATTTATTGAAAGATTAAAGAA
AGTAGAACCTGACTTAGATATAGAAATAAAGGAAATAGTAACTAAGGGCGACCGTATCGTAGATAAACAATTATCTAAAG
TTGGCGGTAAAGGTTTATTTGTGAAAGAAATCCAACAAGAGTTGTTCGATCATGAAATAGATATGGCCATTCACTCATTA
AAAGATGTGCCAAGCGAATTGCCAGATGGATTAACTTTAGGATGTATTCCTGATAGAGAAATTCCACTTGATGCATTTAT
CTCGAAAAATCATGTTCAATTAGCAGATTTACCAGATGGAAGTATTGTAGGAACAAGTTCTTTACGACGCGGTGCTCAAA
TTTTAGCGAAATATCCTAATTTAGAAATTAAATGGATTCGTGGTAATATTGATACGCGTTTGAGTAAATTAGAAACTGAA
GACTACGACGCAATCATTTTAGCAGCAGCTGGATTACGCAGAATGGGTTGGTCTGATGATATTGTAACTGAATATTTAGA
TCCTGAATTACTTGTACCAGCTATCGGCCAAGGTGCACTTGGAATAGAATGCAGAAGCGATGATACAGAACTTCTTGACT
TATTGAGTAAAGTTCATAATCAAGAAGTTGCTGAGTGTGTCACTGCTGAGCGAACATTCTTGAAAGAAATGAACGGAAGC
TGTCAAGTTCCAATCGGAGGATATGCGACAATTGATGATAATGGACGCTTAACTTTTACTGGGTTAATTATGTCTCCAGA
CGGCAAACAACGCTTTGAGCAAACTGCAACTGGAAACGACCCCGTTGAACTTGGTAAAGAAGTCAGCGACATATTAAAAG
AACAGGGTGCAAAAGAAATTATTGACGCTCTGAATGAAGAGTCGTAA

Protein sequence : 
MRKLVVGSRRSKLALTQSRQFIERLKKVEPDLDIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQQELFDHEIDMAIHSL
KDVPSELPDGLTLGCIPDREIPLDAFISKNHVQLADLPDGSIVGTSSLRRGAQILAKYPNLEIKWIRGNIDTRLSKLETE
DYDAIILAAAGLRRMGWSDDIVTEYLDPELLVPAIGQGALGIECRSDDTELLDLLSKVHNQEVAECVTAERTFLKEMNGS
CQVPIGGYATIDDNGRLTFTGLIMSPDGKQRFEQTATGNDPVELGKEVSDILKEQGAKEIIDALNEES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-65 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-65 49