Gene Information

Name : thyA (Sca_1071)
Accession : YP_002634164.1
Strain : Staphylococcus carnosus TM300
Genome accession: NC_012121
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1088051 - 1089004 bp
Length : 954 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAATAAATTTGACAAAGCATACCACGATTTGTGCAAAGAGATTCTTGAAATCGGAAATGAACGTGACGATCGTACACA
TACAGGTACAATTTCAAAGTTCGGCCACCAATTACGGTTTGATTTATCTGAAGGATTTCCATTACTTACTACAAAAAAAG
TTTCGTTTAAATTATTAGCTACTGAACTCGTTTGGTTCATAAAAGGTGATACTAATATCAAATACTTACTTCAATATAAT
AATAATATCTGGAATGAGTGGGCATTTGAAAAATATATTCAATCAGAAGATTATACTGGTCCTGATATGACCAATTTTGG
TCACCGTGCTTTGCAAGACCTTGAGTTTAATGAACGTTATCAAGAAGAAATGGATAAGTTTAAAAAGAAAATTTTAAATG
ACGATGCATTCGCTGAAAAACATGGTGACTTAGGTAATGTTTATGGCAAACAATGGCGTGATTGGGTAGGTGCAGATGGA
AAGCATTATGATCAACTTGCTACTGTTATTAAGCAAATTAAAAAGCATCCTACTTCACGCAGACATATTGTATCCGCTTG
GAACCCATCGGAAATTGACACAATGGCTCTCCCACCATGTCATACAATGTTTCAATTTTATGTACAAGATGGCAAGTTAA
GTTGCCAACTTTATCAGAGAAGTGCGGATATTTTCTTAGGAGTTCCTTTTAATATTGCAAGTTATAGTTTGTTAACGCAT
TTAGTTGCTAAAGAATGTGGTTTAGAAGTGGGAGAATTTGTACATACATTCGGAGACGCTCATATTTATTCAAACCATAT
AGATGCTATTGAAAAACAACTCTCAAGAGATAGTTATGCTCCACCGCAATTAAAAATCAATACTGATAAATCCATTTTTG
AAATTCAATATGAAGATTTGGAAATCGTAAATTATCAATCGCATCCAGGTATTAAAGCACCTATCGCAGTATAA

Protein sequence :
MNKFDKAYHDLCKEILEIGNERDDRTHTGTISKFGHQLRFDLSEGFPLLTTKKVSFKLLATELVWFIKGDTNIKYLLQYN
NNIWNEWAFEKYIQSEDYTGPDMTNFGHRALQDLEFNERYQEEMDKFKKKILNDDAFAEKHGDLGNVYGKQWRDWVGADG
KHYDQLATVIKQIKKHPTSRRHIVSAWNPSEIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYSLLTH
LVAKECGLEVGEFVHTFGDAHIYSNHIDAIEKQLSRDSYAPPQLKINTDKSIFEIQYEDLEIVNYQSHPGIKAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 2e-130 83