Gene Information

Name : tkt (NAMH_1685)
Accession : YP_002608065.1
Strain : Nautilia profundicola AmH
Genome accession: NC_012115
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1572920 - 1574776 bp
Length : 1857 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAACTTAAGAAAAAAAATGGCGGATACGATCAGATTTTTAGCTGCCGATATGGTGCAAAAAGCAAATTCGGGGCATCC
CGGTGCGGCTTTGGGGCTTGCTGATATTATGACGGTGTTTAGTGAAGTAGTAAATATCACTCCTCATAATCCGGAATTTG
TAAACAGAGACAGGGTAGTGTTCTCAGGTGGGCATGCGACTCCTCTTATTTATTCAATGCTTTTCCTTTGGGGGTATGAC
ATTACTTTGGATGATCTGAAAAACTTCAGACAATTAGGAAGCAAAACCCCGGGACATCCGGAATTTGGTCATACTCCTGG
AATTGAAGTAACTACCGGACCTCTTGGGCAGGGTGTGGCAAATGCGGTTGGATTTGCAAAGGCTAAAAAGTTTATGAGTC
TTAAATTTCCGGAAATAAACCACAAAGTATGGTGTTTTTGCGGTGACGGGGATTTGGAAGAAGGAATTTCTTATGAAGCA
TGTTCTTTAGCAGGGAAACACAAACTTGAAGATTTAATAATTATATACGACAGTAACAATATTTCAATCGAAGGCGAAGT
AAGTATAGCTTTTGATGAGGATGTTCAAAAAAGATTCGAATCACAAGGATTCAGAGTTCTTGAAATGAACGGGCACGATT
ATGAAGATATTGAAAAAAAATTAAACGAAGCCAAAAACAGCGACGGAAGACCTACTTTAATTATCGCCAAAACAGTAATA
GCAAGAGGAGCGGTAGGGCTTGAAGGAAGTGAAAAAACCCACGGTGCGCCTTTAGGTGAGGATGTAATTAAAAAATCAAA
AGAAGCCGCGGGATTTGATCCTGAAAAAACTTTCATTGTTCCTGAAGACGTACTTGTAAGATTCAGATGTGTAAAAGAAA
GAGGAGAAGTAATTGAGGCTGAATTTAATAAAAAAGCAAATGCAGGAGAAATTAAAGCATTTTTTGAAAAAGACTTCAGT
AAAATCAAATGGCCTGAATTTGAAGAAGGCGCAAGTATCGCTACAAGAAAAAGCAACGGTGAAATTCTTAATGCCATAGC
TAAAGCGGTTCCGAGTTTCCTCGGTGGAAGTGCGGATTTGGCACCGTCAAATAATACGATTCTTAAAGATGAAGATGATT
TCCCACACGGAAGAAACCTGCATTACGGAATCAGAGAACATGCAATGGCGGCAATTAACAACGCATTCAGCGCATACGGA
TTTTTACCGTATGCCGCTACATTTTTGGTGTTTAGTGATTATTTAAGAGGCGCTCTTAGAATTGCGGCGCTTAGCAGCCA
TAAAAACTACTGGATTTTTACTCACGACAGTATCGTAGTAGGTGAAGACGGCCCTACTCATCAGCCGGTTGAACATATTA
CTTCTTTAAGAGCAATTCCGAATCTATACGTATTCAGACCTGCAGACGCCAATGAAAATGTAAACGCATGGAAAGCGGCA
CTTGATATCGATGCTCCTGTAGTATTTGCGTTAAGCAGACAGGGGCTTAGAAACATAAGTCCTAAAGACGCGGATTTAAG
CAAGGGTGCATATATTTTAAGAGAAGGAAACAGCGATATTACACTTGTAGCAAGCGGAAGCGAAGTTAATCTGGCTGTAG
ATGTTGCAAAAAGACTTGATGCGAGAGTTGTAAGTGTTCCTTGTTTTGACTTGTTTGACGAGCAGGATGAAGAATTTAAA
TCGTCTCTTTTCAAAGGCAGAGTAATCGCAATAGAAGCAAACAGAGCATTTGAATGGTATAAATACGCCGATGAGGTAAT
AGGAATGAATACATTCGGTGCAAGCGGTAAAGGCGGTGATGTATATAAACATTTCGGATTTGACGTAGATGCGATTGTAG
AAAGGATTGAAAAATGA

Protein sequence :
MNLRKKMADTIRFLAADMVQKANSGHPGAALGLADIMTVFSEVVNITPHNPEFVNRDRVVFSGGHATPLIYSMLFLWGYD
ITLDDLKNFRQLGSKTPGHPEFGHTPGIEVTTGPLGQGVANAVGFAKAKKFMSLKFPEINHKVWCFCGDGDLEEGISYEA
CSLAGKHKLEDLIIIYDSNNISIEGEVSIAFDEDVQKRFESQGFRVLEMNGHDYEDIEKKLNEAKNSDGRPTLIIAKTVI
ARGAVGLEGSEKTHGAPLGEDVIKKSKEAAGFDPEKTFIVPEDVLVRFRCVKERGEVIEAEFNKKANAGEIKAFFEKDFS
KIKWPEFEEGASIATRKSNGEILNAIAKAVPSFLGGSADLAPSNNTILKDEDDFPHGRNLHYGIREHAMAAINNAFSAYG
FLPYAATFLVFSDYLRGALRIAALSSHKNYWIFTHDSIVVGEDGPTHQPVEHITSLRAIPNLYVFRPADANENVNAWKAA
LDIDAPVVFALSRQGLRNISPKDADLSKGAYILREGNSDITLVASGSEVNLAVDVAKRLDARVVSVPCFDLFDEQDEEFK
SSLFKGRVIAIEANRAFEWYKYADEVIGMNTFGASGKGGDVYKHFGFDVDAIVERIEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-112 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-101 41