Gene Information

Name : mdtC (HRM2_34050)
Accession : YP_002604644.1
Strain : Desulfobacterium autotrophicum HRM2
Genome accession: NC_012108
Putative virulence/resistance : Resistance
Product : protein MdtC
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 3854307 - 3857348 bp
Length : 3042 bp
Strand : -
Note : multidrug resistance protein MdtC (cation/multidrug efflux pump MdtC)

DNA sequence :
ATGAACCCGGCCCGATTTGCTCTTAACAGACGAACATTCCTGGCAATCTTGACCCTGCTTCTGATCGGGGGAGGTCTCCT
GGCCTTTGAACATCTGGGACGACTTGAAGATCCCACCTTTACCATTAAAACAGCCCTTGTGATTACCCCCTATCCCGGTG
CTACACCCCTGGAGGTGGAAGAGGAGATTACGGAGAAGGTTGAGGAGGCCATCAAATCCATGGGCCAGGTCAAGGAAATC
TATTCGACCTCCCAGGAGGGCATCTCCTTTGTGTATGTGGAGATGAAGGATGCGTTCAACAAACGAGAGTTGCCCCAGAT
CTGGGATGAACTCAGAAGAAAGGTGGCTGATATCCAGGCGACCCTTCCCCCTGGAGCAGGGCCGTCCCAGGTTAACGATG
ATTTCGGTGATGTTTACGGGGTTTTCTTTGCCTTGACCGGTGATAATTACACCCTGGCCCAGCTAAAGGACCAGGCTGAA
TATCTTAAGAAAGAGCTGCTCCTGTGCAAGGATGTGGCAAAAATAGATTTCTGGGGAATCCAGCAGCAGGTCCTTTATAT
CGAGTTCGAGCCCAGTAAACTTGCCGGGCTGGGTATTTCTCCTGATTTGATCTACCAGACCCTTCACCTCCAGAACGTTG
TGGAATCAAGCGGTAAGGTGGATGTCAATACCGAATACATGCGTATCTCCCCCACGGGCGAGTTCAAGAGTGAAACCATG
ATTGCTGATCTTTTGATCGGTGGGGCCGGTTCAATGGTCAGGCTTGGAGACATCGCCACAATCACGAGGGGATACTGGGA
ACCGCCCAGGAACATGATGCGATACAACGGTCGTCCCTGCATCGGCATTGGCGTTTCCACCGTGGATGGCGGCAATGTCA
TCACCATGGGAGATTCGGTGAGGGAAAAACTCCATGAACTTGAGGCCCGGCAGCCGCCGGGTATGGCCCTTAATACCATT
TATTACCAGAGCCGTGTGGTGACTGAATCGGTGAACGCCTTTCTTATAAACCTGGCAGAGGCGGTGGTCATTGTGGTGGT
GCTGCTCATGATTTTCATGGGATGGCAGAGCGGCATGCTCATCGGTATCATCCTTTTGCTGACCATCCTTGGAACTTTCA
TGGGCATGCTGCTCATGGGGATCGATCTTCAGAAAATTTCCCTTGGTGCCCTGATCCTTGCCCTGGGCATGCTGGTTGAC
AACGCAATCGTGGTGACGGACGGCATCCTTGTGCGGGTCACCCGGGGGGAAAGCCGGGAGAGTGCTGCCGTCCAGGTGGT
CAGGGAAAACCAGTGGCCCCTGTTGGGAGCCACCTTTGTGGCCATCCTGGCATTTGCCGCCATTGGGTATGCCCCGGGAA
ATGTGGGTGAATTCTGCAGGTCCCTGTTCCAGGTCATGGCCCTTTCTCTGTTGCTCAGCTGGCTTTTTGCCGTAACCATT
ACTCCGCTTTTCTGCGTGTGGTTTCTCAAGACCCCGGAATCACAGGCGATGAAAGATCCCTATGGCTCAAGGATTTTTCG
CATCTACCGGCGCATGCTCCATCTGGCCCTCAGGTGGCGCTATCTGACACTGGTGGTTGTCAGCCTGCTGATGTTGCTGT
CGATCATCGGGTTTGGTTCCATCCCTTCTGCTTTTTTTCCTGACTCCACCCAGCGTTATTTTTACGTAAACTTCTGGAAG
TCCCAGGGAACCCATATCAACCATACGGCCGACGATCTGGCAAAGATTGAACAATTTGTTCGGCAGATGGATGGGGTGAA
AAATATCACCACCTTTGCAGGAGAAGGGGCCCTCAGGTTTCTTCTCTCCTATGATTACCAGATTCCCAATCCAAGTTACG
GCCAGCTGCTGGTGGAGGTTGACGATTATCTCCAGATTAACGGGCTTGTCAAACAGGTCAACGCTTATCTTGCGGCAAAT
TTTCCCGATGCCGAGCCCTATGCACGAAAGATAGTTTCCGGGCCACCCGTCACCTTTCAGGTGGAGGCAAGATTTAGGGG
ACCTGATATCAAGGTTCTACAGGATCTTGCCGACCAGGCCGGAAAGATCATGGAGCAGACCCCGAACACCCGGGACGTAA
GAACCGACTGGCGCCAGCAGGTACGGGTGATAAGACCTGAATTCTCCCAGAGTCAGGCCCGCAGGTCAGGAGTCACAAGG
AGTGAGTTTTCCAGTGCGTTGAAGTGGCAGTTCACAGGCGTTGTGGCCGGGCTCTACAGGGAGGGGGACGAACTGATTCC
CATCATTACCCGGCCGCCGGAAAAACAACGCAATTCAGTGGGCGACCTTGACAATGTCCAGATTTACAGCCATGCGAACC
GTTTGTTTATTCCCATTAATCAAGTCATCACCGGGGTGAAAACCGTCTGGGAATGGCCCCTGATAGGTCACCGGGATCAG
CAGCGGGCCGTGACGGTTCAGTGTAACCCCGCCAGGGGTCTTGCCGCTCCCCTTCGCCTTGCCATGGCCCAGAAGATTGA
AGCCCTTGATCTTCCTCCGGGTTACAGCCTTGAGTGGGCCGGCGAGTTTGAAGCCTCAAACGATGCAAGGGAACCTTTGG
GCAAAATATTTCCCCTTTGCGTGCTCGGGATGTTTGTCATTGTGGTCGGTCTGTTCAACTCCGTTCGAACGCCCCTGGTC
ATCTTTCTGACCGTGCCCCTTTCCATCATGGGGATTGCCGCCGGGCTTTTGATCATGGATCTGCCCTTTGGCTTCATGGC
CATCCTGGGCTTTCTGGGGCTCAGCGGCATGCTGATCAAGAATGCCATTGTACTGATCGAACAGGTGGAAATTTTTTTGA
AAGAGGATTACCCCCCCTACAAGGCTATTCTGGATAGCTCTGTCAGCCGCATGCGGCCCGTGATCATGGCTTCTGGAACC
ACCATTCTGGGCATGCTGCCCCTGGTCTTTGATCCCATGTTCGCGACCATGGCCGTCACCATCATGGGTGGTCTTTTTGT
GGCAACTTTTTTAACCCTGATTGTTGTTCCGCTGCTCTATTGTCTATTTTACCGGATTAAGTCAGAGAAGCGGTATCTAT
GA

Protein sequence :
MNPARFALNRRTFLAILTLLLIGGGLLAFEHLGRLEDPTFTIKTALVITPYPGATPLEVEEEITEKVEEAIKSMGQVKEI
YSTSQEGISFVYVEMKDAFNKRELPQIWDELRRKVADIQATLPPGAGPSQVNDDFGDVYGVFFALTGDNYTLAQLKDQAE
YLKKELLLCKDVAKIDFWGIQQQVLYIEFEPSKLAGLGISPDLIYQTLHLQNVVESSGKVDVNTEYMRISPTGEFKSETM
IADLLIGGAGSMVRLGDIATITRGYWEPPRNMMRYNGRPCIGIGVSTVDGGNVITMGDSVREKLHELEARQPPGMALNTI
YYQSRVVTESVNAFLINLAEAVVIVVVLLMIFMGWQSGMLIGIILLLTILGTFMGMLLMGIDLQKISLGALILALGMLVD
NAIVVTDGILVRVTRGESRESAAVQVVRENQWPLLGATFVAILAFAAIGYAPGNVGEFCRSLFQVMALSLLLSWLFAVTI
TPLFCVWFLKTPESQAMKDPYGSRIFRIYRRMLHLALRWRYLTLVVVSLLMLLSIIGFGSIPSAFFPDSTQRYFYVNFWK
SQGTHINHTADDLAKIEQFVRQMDGVKNITTFAGEGALRFLLSYDYQIPNPSYGQLLVEVDDYLQINGLVKQVNAYLAAN
FPDAEPYARKIVSGPPVTFQVEARFRGPDIKVLQDLADQAGKIMEQTPNTRDVRTDWRQQVRVIRPEFSQSQARRSGVTR
SEFSSALKWQFTGVVAGLYREGDELIPIITRPPEKQRNSVGDLDNVQIYSHANRLFIPINQVITGVKTVWEWPLIGHRDQ
QRAVTVQCNPARGLAAPLRLAMAQKIEALDLPPGYSLEWAGEFEASNDAREPLGKIFPLCVLGMFVIVVGLFNSVRTPLV
IFLTVPLSIMGIAAGLLIMDLPFGFMAILGFLGLSGMLIKNAIVLIEQVEIFLKEDYPPYKAILDSSVSRMRPVIMASGT
TILGMLPLVFDPMFATMAVTIMGGLFVATFLTLIVVPLLYCLFYRIKSEKRYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 4e-178 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mdtC YP_002604644.1 protein MdtC BAC0519 Protein 0.0 46
mdtC YP_002604644.1 protein MdtC BAC0428 Protein 0.0 45
mdtC YP_002604644.1 protein MdtC BAC0425 Protein 2e-178 44
mdtC YP_002604644.1 protein MdtC BAC0526 Protein 3e-178 44