Gene Information

Name : clpB (HRM2_25080)
Accession : YP_002603766.1
Strain : Desulfobacterium autotrophicum HRM2
Genome accession: NC_012108
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2863209 - 2865788 bp
Length : 2580 bp
Strand : +
Note : ATP-dependent two-component protease ClpB (ATP-binding-N/ATPAse-C)

DNA sequence :
ATGAAATTTGACAAACTCACCATCAAGTCCCAGGAATTGATCCAGACAGCCCATGACCTGGCACTTAGAAAAAACAATCA
GGCCATTGATCCCGTGCATTTCCTGAAGGCCATTCTGCTGGATGACCAGGGAATGTCCACGGCCATCCTCAATAAAATCG
GTGCTTCAACCGACAATCTCATGACCTTTACCGACCAGGCCATTGATGCCCTTGCAAAGGTGGAGGGGGGAGGGGATCTT
TTTTTATCGGTTCCTTCAAAAAAGATCCTGGATACCGCCTTTGTTGAGGCAGAGGGTATGAAGGATCAGTATGTGAGCCA
GGAACATATCCTTCTTGCCCTTTGCATTGCCAAGGACAAGCCCCGTGAACTCTTGAACAAAGAGGGGGTCACCAAGGATA
AAATCCTGACCGTTCTAAAGGAGATGCGGGGGGGCCAGACCATTGATTCGCCCAATCCTGAGAATACCTTCCAGGCCCTT
GAAAAGTACGGCAGGGACTTGACCGAACTTGCCCGACTGGGAAAGCTTGACCCGGTCATCGGAAGGGACGATGAGATCCG
ACGGGTGGTCCAGGTGCTTTCAAGGCGACGTAAAAACAATCCTGTGCTCATTGGCGAACCTGGCGTTGGAAAAACCGCCA
TCATCGAAGGGCTTGCCCAGCGAATCGTTGCTGGCGATGTCTCTGAAACCCTGAGAAATCGACGGGTAGTCGCCCTGGAC
ATGGGAGCGCTTCTTGCCGGTGCAAAGTTCAGGGGTGAATTTGAAGAACGGCTCAAGGCCGTATTAAAAGAGGTGGAACG
GGCTGAAGGTCAGGTGGTCCTGTTTATTGATGAGCTCCACACCGTGGTTGGTGCCGGCGCATCTGAAGGATCGGTGGACG
CTTCTAACATGCTCAAACCTTCGCTTGCCAGGGGAACCCTGCGATGTATTGGTGCGACAACCCTTAACGAATACCGTCGT
TACATTGAAAAGGATGCGGCTCTGGAGCGTCGATTCCAGCCGATTCTGGCAAAGGAACCCACGGTTGAAGACACGATTTC
CATCCTCAGGGGCTTAAAGGAAAAGTATGAGGTGTACCATGGGATAAGGATCAAGGATTCGGCCCTTGTGGCAGCAGCCA
CCCTGTCAAAACGCTATATCACGGACCGTTTCCTGCCGGACAAGGCCATAGATCTCATTGACGAATGCGCCTCAAGACTC
AGGATCGAAATCGACACCATGCCCGTTGCCATTGACGAACTCCAGCGACGGATGGTCCAGATCGAAATAGAACGCCAGGG
GCTGAAAAAAGAGACCGACCCGTCGTCAAAATCCCGGAAAGAGAAACTGGATCGGGATCTTGCCGAGATCAACGAGGAAA
TCCGACCCATGCGGCTCCATTGGGAAAATGAAAAACGGCTGATCCAGGAAATTGGCAAGATCCGGGAAGAGATCGACAAT
GCTGTAACCCTGGCAAAGCGTGCCGAGCGTGAGGGTGATCTTGCCCGTGTGGCAAAAATTCGGTATTCAACCCTTGCCGA
GTTCCAGACCCAACTGGACAAGAAAAAAGCTGATTTAAGGCTCCTCCAGGCCGAGCGCAGAATGCTCAAGGAGGATGTGG
AAGAGTCAGACATTGCCGAAGTGGTTTCCTCGTGGACCCATATCCCGGTTGCCACCATGCTCAAGGGTGAACGCGAAAAA
CTGATTCACATGGAAGAGGCCCTGGAACAAAGGGTTATCGGTCAGAAAGACGCCATCAAGGCCGTTTCAGATGCCGTGCG
CCGGGCCCGATCTGGGCTAAAACCCCAGGATCGGCCCATTGGGACCTTTATCTTCATGGGGCCCACAGGTGTGGGTAAGA
CAGAGTTGACAAAGGCCGTTGCCGAATTCATCTTTAATACAAAGAATGCCATGGTAAGGATTGATATGTCCGAATACATG
GAAAAACATTCGGTGGCAAGACTGATCGGTGCCCCTCCGGGTTATGTGGGATACGAAGAGGGTGGTTATCTCACCGAGGC
TGTTCGGCGTCAGCCCTATTCCGTTGTTTTGTTTGACGAAATTGAAAAGGCCCATCCCGATGTATTCAACGTGCTGCTCC
AGGTGTTAGATGACGGACGAATGACCGACGGCCATGGCAGAACGGTGGATTTTACCAACACCATTCTCATCATGACCTCC
AATGTGGGGTCCCGCATGATCCAGGAATCAGGGGGGAAAGATATCCAGGACAAGATCAACCAGGCCCTGTCCCAGACTTT
TAAACCTGAATTTTTGAACCGTATCGATGAGATCATCGTATTCCACGGACTTGAGATGGAGCACATCAGGGCCATCGCAT
CCATCCAGATCCAGCACCTGAACCAGCGGCTTGAAGCAAAAAAGATAGCCATTACCCTTGACGAGGCCGCCATGGCATTC
ATAGCACAAAAGGGGTTTGATCCTGTGTTTGGCGCACGTCCCCTCAGGCGAGTGATTCAGCAGGAGATCGAAAATCCGCT
GTCCCTTGAAATTTTAAAGGGAACGGTGGTTGAAGGCCAGCAGGTAACCTTTACCGTTGACCCAGGGAATACAAAACTTG
TCCTGGGTCCCCGGTCATAG

Protein sequence :
MKFDKLTIKSQELIQTAHDLALRKNNQAIDPVHFLKAILLDDQGMSTAILNKIGASTDNLMTFTDQAIDALAKVEGGGDL
FLSVPSKKILDTAFVEAEGMKDQYVSQEHILLALCIAKDKPRELLNKEGVTKDKILTVLKEMRGGQTIDSPNPENTFQAL
EKYGRDLTELARLGKLDPVIGRDDEIRRVVQVLSRRRKNNPVLIGEPGVGKTAIIEGLAQRIVAGDVSETLRNRRVVALD
MGALLAGAKFRGEFEERLKAVLKEVERAEGQVVLFIDELHTVVGAGASEGSVDASNMLKPSLARGTLRCIGATTLNEYRR
YIEKDAALERRFQPILAKEPTVEDTISILRGLKEKYEVYHGIRIKDSALVAAATLSKRYITDRFLPDKAIDLIDECASRL
RIEIDTMPVAIDELQRRMVQIEIERQGLKKETDPSSKSRKEKLDRDLAEINEEIRPMRLHWENEKRLIQEIGKIREEIDN
AVTLAKRAEREGDLARVAKIRYSTLAEFQTQLDKKKADLRLLQAERRMLKEDVEESDIAEVVSSWTHIPVATMLKGEREK
LIHMEEALEQRVIGQKDAIKAVSDAVRRARSGLKPQDRPIGTFIFMGPTGVGKTELTKAVAEFIFNTKNAMVRIDMSEYM
EKHSVARLIGAPPGYVGYEEGGYLTEAVRRQPYSVVLFDEIEKAHPDVFNVLLQVLDDGRMTDGHGRTVDFTNTILIMTS
NVGSRMIQESGGKDIQDKINQALSQTFKPEFLNRIDEIIVFHGLEMEHIRAIASIQIQHLNQRLEAKKIAITLDEAAMAF
IAQKGFDPVFGARPLRRVIQQEIENPLSLEILKGTVVEGQQVTFTVDPGNTKLVLGPRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-105 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_002603766.1 chaperone ClpB VFG2076 Protein 1e-110 41