Gene Information

Name : lysS (Cla_0488)
Accession : YP_002575087.1
Strain : Campylobacter lari RM2100
Genome accession: NC_012039
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 463376 - 464878 bp
Length : 1503 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTGATAATATTTTAGAGCAACAAAAAATTCAAAAAGCGCAAGAGTTAAAAGAATTAGGAATCAACCCTTATCCGCA
CTTTTTAAAAAAAGAAATGAGTATAAGTGAATATAAGGCTAAATTTACCTATATTAAAGATATGGAAAATCAGCGCGATG
AAAATGCTCATGGAGTATTAGCAGGAAGATTAAAGCTTCTTAGGATAGCTGGTAAATCAGTATTTGCTAATATAGAAGAT
GAGCAAGACAATTTACAAATTTATTTTAATCAAAATATCTTAGGAGAAGAATACTTTGCCATTTTAAAAAAATATCTTGA
AGTAGGGGATATTGTTTTGGTTAAAGGTTTTCCTTTTATGACAAAAACAGGAGAATTCAGTCTTCATGTAGAGCAAATTC
AAATAGCTACAAAAGCTATAGTGCCTTTACCAGAAAAATATCATGGGCTGACAGATATTGAGCAAAGATATAGAAAAAGA
TATCTTGATATGATTATGAATAGTGAGGTGAGAAAAGATTTTATTTTGCGCTCTAAAATCGTTTCTTATATTAGATCTTT
TTTTGATAATAAAGGATTTTTGGAAGTTGAAACACCAATGATGCATCCTATTGCAGGAGGAGCAAATGCAAAACCTTTTG
TGACTTATCACAATGCTTTGGGTGTGGAAAGATTCTTAAGAATTGCTCCAGAATTATATCTAAAACGTTTGATTGTAGGT
GGTTTTGAAGCGGTTTATGAGATTAATAGATGTTTTAGAAATGAAGGGATGGATTTAACGCACAATCCTGAATTTACTAC
AATTGAGTTTTATTGGGCTTATCATAATTATCATGATTTAATGGATTTAACAGAAGAGCTTTTTGCTATGCTTTTAGATA
AGTTAAATTTAGATAAAAAACTTGAATTTGATGAAAAAATAATTGATTTTTCTAAGTCATTTGAAAGAATTACTTATAAA
GACGCATTAAAAAAATACGGTGGTTTGGATGATGAGCTTATTAACAATAAAGAATTAATCTTGAAAAAGCTAAAAAAAGA
TGGATTTGAAGCCAATGAAAAATTGGAATTAGGCCATTTGCAAGCTGAACTTTTTGATAATTATGTTGAAGATAAATTGA
TTAATCCTACTTTTGTGATAGATTTTCCTATTTCTATAAGTCCTTTATCTAGAAGAAGTGATAAAGATGCAGATATTGCT
GAAAGATTTGAGTTGTTTATCGCAGGCAGAGAAATTGCTAATGGATTTAACGAGCTTAATGATCCACTAGATCAATATGA
GAGATTTTTAAAGCAAATTGAAGCAAAAAATGCAGGTGATGAAGAAGCATGTGAAATGGATGAGGATTTTGTTAATGCAT
TAGGTTATGCTATGGCACCAACTGCAGGACAAGGCATAGGAATAGATAGATTAGTCATGCTTTTAATTAATAAAAAATCA
ATTCGTGATGTAGTACTTTTCCCAGCTATGAGACCACTTAAAAATGAGATAAAAGGAGAGTAA

Protein sequence :
MFDNILEQQKIQKAQELKELGINPYPHFLKKEMSISEYKAKFTYIKDMENQRDENAHGVLAGRLKLLRIAGKSVFANIED
EQDNLQIYFNQNILGEEYFAILKKYLEVGDIVLVKGFPFMTKTGEFSLHVEQIQIATKAIVPLPEKYHGLTDIEQRYRKR
YLDMIMNSEVRKDFILRSKIVSYIRSFFDNKGFLEVETPMMHPIAGGANAKPFVTYHNALGVERFLRIAPELYLKRLIVG
GFEAVYEINRCFRNEGMDLTHNPEFTTIEFYWAYHNYHDLMDLTEELFAMLLDKLNLDKKLEFDEKIIDFSKSFERITYK
DALKKYGGLDDELINNKELILKKLKKDGFEANEKLELGHLQAELFDNYVEDKLINPTFVIDFPISISPLSRRSDKDADIA
ERFELFIAGREIANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYAMAPTAGQGIGIDRLVMLLINKKS
IRDVVLFPAMRPLKNEIKGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-100 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002575087.1 lysyl-tRNA synthetase VFG1668 Protein 2e-100 46