Gene Information

Name : Athe_0872 (Athe_0872)
Accession : YP_002572755.1
Strain : Caldicellulosiruptor bescii DSM 6725
Genome accession: NC_012034
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 971516 - 972778 bp
Length : 1263 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATTTAAAATATATAAGGGCAAACCCGGAAAAGGTACAAGAAGGACTTTCTAAGAGAAACAAAGACGTTTCAAT
TGCGCCCATTTTAGAGCTTGATGAAAGAAGAAGAAAGCTTTTGGCTGAGGTTGAAAGTCTGAAAGCTCTACAGAATCAAA
AATCAAAAGAGGTCCCAAAGCTCAAAAAGGAAGGAAAAGATGTTACAGATCTTATGAATGAGCTAAAAGATCTATCTGAT
AAAATTAAAGAATTAGATAGCAAAGTCAAAGAGGTTGAAGATGAGATAGAAAAGATTTTGCTCACAATTCCAAACATTCC
TCATGAGTCTGTACCAGTTGGAAAAGATGATACAGAAAATGTTGAAGTAAGGCGCTGGGGTGAGGTAAGAGAACCTGACT
TTGAAATAAAGCCTCATTGGGAAATTGGTGTAAATCTTGGAATCTTGGATTTTGAAAGAGCCTCAAAAGTGTCAGGAAGC
CGTTTTACATTTTACAGAGGACTTGGTGCAAGGTTAGAAAGAGCTTTAATCAACTTCATGCTTGACCTTCACATTGAAAA
GCATGGCTATACTGAGCTATTCCCACCTTTTTTAGTTGCGCGAAAATCTATGATAGGCACAGGACAGCTTCCAAAATTTG
AAGAGGATGCATTTAAGACAACAGATGATTACTTTTTGATACCAACAGCAGAAGTTCCTGTTACAAACTACCACAGAGAA
GAGATACTCAAAGAAGAAGACTTGCCAATAAAATATGTTGCCTACTCAGCATGTTTTAGGGCAGAAGCTGGTGCTGCTGG
CAAAGACACAAGAGGGCTTATTCGTCAGCATCAGTTTAACAAGGTTGAGCTTGTAAAGTTTACAAAGCCAGAAGATTCTT
ATGATGAGCTTGAAAAACTCACAGCTGATGCAGAGGATGTTTTAAAGGAATTGGGACTTCCTTACAGGGTTGTTCTTCTT
TGTTCGGGTGATTTAGGATTTTCTTCTGCAAAGACATACGACATTGAAGTCTGGATGCCAAGCTATGGAAGATATGTTGA
GATTTCTTCTTGTTCAAACTTTGAAAACTATCAGGCACGAAGAGCAAACATCAGATTCAGAAGGAAAGACGGAAAACTTG
ACTATGTTCATACACTCAACGGCTCAGGCCTTGCTGTGGGAAGAACCTTAGCAGCAATACTTGAAAACTTCCAGCAGAAA
GATGGAACAGTAGTTGTTCCAGAGGTTTTGAGAAAGTATATGGGTACAGATGTGATAAAGTAA

Protein sequence :
MLDLKYIRANPEKVQEGLSKRNKDVSIAPILELDERRRKLLAEVESLKALQNQKSKEVPKLKKEGKDVTDLMNELKDLSD
KIKELDSKVKEVEDEIEKILLTIPNIPHESVPVGKDDTENVEVRRWGEVREPDFEIKPHWEIGVNLGILDFERASKVSGS
RFTFYRGLGARLERALINFMLDLHIEKHGYTELFPPFLVARKSMIGTGQLPKFEEDAFKTTDDYFLIPTAEVPVTNYHRE
EILKEEDLPIKYVAYSACFRAEAGAAGKDTRGLIRQHQFNKVELVKFTKPEDSYDELEKLTADAEDVLKELGLPYRVVLL
CSGDLGFSSAKTYDIEVWMPSYGRYVEISSCSNFENYQARRANIRFRRKDGKLDYVHTLNGSGLAVGRTLAAILENFQQK
DGTVVVPEVLRKYMGTDVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 9e-115 58