Gene Information

Name : smpB (Athe_0463)
Accession : YP_002572368.1
Strain : Caldicellulosiruptor bescii DSM 6725
Genome accession: NC_012034
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 530141 - 530617 bp
Length : 477 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGTCTGAAAAGAATAAACAGAATGACATAAAAGTCATAGCAACAAACCGCAAAGCTTATCATGACTACTTCATCGAAGA
GACAATCGAAGCAGGAATTGAGCTAAAAGGCACAGAAGTAAAGTCGGTGCGCCTTGGTCATGTTAATCTCAAAGACAGTT
TTGCCAGGGTTGAAAATGGAGAGGTCTTTCTCTACAACATGCATATAAGTCCATATGAAAAAGGCAACATCTTTAACGTT
GACCCAATGAGAGATAGAAAATTACTCTTGCACAAACATGAAATCAACAGGCTTGCGGGTTATGTTCAGCAAAAAGGTTA
CACTTTAATCCCATTGAAGATTTACATCAAAAGAGGTAAAATAAAAGTAGAGCTTGCAGTTGCAAAGGGTAAAAAACTGT
ACGACAAGCGTGAGGCAATAGCAAAAAGAGACGCTGAGCTTGAGATAAGAAAGAAGATGAAAGAGTATTTAAGATGA

Protein sequence :
MSEKNKQNDIKVIATNRKAYHDYFIEETIEAGIELKGTEVKSVRLGHVNLKDSFARVENGEVFLYNMHISPYEKGNIFNV
DPMRDRKLLLHKHEINRLAGYVQQKGYTLIPLKIYIKRGKIKVELAVAKGKKLYDKREAIAKRDAELEIRKKMKEYLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-35 58
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 7e-29 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-24 42