Gene Information

Name : Athe_1825 (Athe_1825)
Accession : YP_002573691.1
Strain : Caldicellulosiruptor bescii DSM 6725
Genome accession: NC_012034
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1899152 - 1901641 bp
Length : 2490 bp
Strand : -
Note : PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: csc:Csac_2367 ATPase

DNA sequence :
ATGTTTCAAGGAAGGTTTACAGAAAGAGCTGAGAAAGCAATAATGCTTGCGCAGCAGGCTGCTGCCGAGCTTGGTCATAA
CTATGTTGGAACAGAGCACTTGCTTTTGGGACTTATAAGAGAAGGTGGTGGCATTGCTGCAAGAGTTTTGCAAAGCCAGG
GTGTTACTGAAGAAAAGGTTATTGATGAAATTGAAGAGCTAATTGGAAGAGGCGATTATCAGCTTCCACAGCCACCGACA
GGTTTTACCCCAAGGACCAAAAGAGTGTTTGAGATTGCCTTTATGGAAGCGCGAAGACTTGGCAGCAGTTATATCAGCAC
AGAACATATCCTGCTTGCGATAATGAGAGAAGGAGAAAGTGTTGCTGTCAGGATTTTAATGGACCTTGGTGTTGACCCGC
AGAGACTTTTTGAAGAGATAATGAAGCTTTTGAACGAGGATGCAAAAAATGTTGGTGGTGTATCTCCTCAGCAGCAGATC
AATTTCCAAACACAGAACACTCCAACGTTAAATCAGTTTAGTAGGGACCTTACACAGCTTGCGCTTGAGGGCAAAATTGA
CCCTGTAATTGGCCGTGAGAAGGAGATAGAGAGAGTTATTCAAATTTTGTCAAGAAGAACAAAGAACAATCCGTGCTTGA
TTGGTGAGCCGGGGGTTGGTAAGACTGCCATTGTTGAAGGGCTTGCACAAAAGATTGTTGAGGGAAATGTTCCAGAACTT
TTGAGAAATAAAAGAGTTGTGGCTTTAGACCTTTCCGCTATGGTTGCAGGGTCAAAATTCAGAGGAGAGTTTGAAGAAAG
GCTCAAAAAAGCTATGGAAGAGGTTAGAAAAGCAGGAAATGTAATTCTGTTTATTGATGAGATGCACACTATAATAGGTG
CTGGTGCAGCAGAAGGTGCAATCGATGCGTCAAACATCTTAAAACCTGCTCTTGCACGCGGTGAGATACAGGTAATTGGT
GCAACTACACTTGATGAGTACAGAAAACACATAGAAAAAGATGCTGCACTTGAGCGAAGATTCCAACCAATTTTGGTTGG
TGAGCCAACACCTGAAGAGGCTATACAGATTTTAAAAGGTCTTAGAGACAAATACGAAGCTCATCATGGTGTAAAGATAA
CTGATGAGGCTATAAAAGCTGCTGTTGAGCTGTCTACTAAATATATTACAGATAGATACTTGCCGGACAAAGCAATTGAC
CTTATTGATGAAGCAGCATCAAGAGTGAGACTCAGAATGTACACACTGCCACCGCATGTTAAGGAGTTTGAAGAGAAGAT
TGAAAAGCTTGAAAAAGAAAAGGAAGAGGCTATAAGACTTCAGGAGTACGAAAAAGCTGCAAAGATAAGAGATGAAATAA
TGAAACTTCGCCAAGAGCTTGAAAAGATAAAAAATTCATGGACAAATGACCAGCAAAAGACACAGCCAATTGTTACAGAA
GATGATATAGCGTACATTGTATCAAGCTGGACAGGGATTCCGGTAAATAAACTTACCGAAGATGAATCTGAAAGACTTTT
AAAGCTTGAAGAGGTTTTGCACAGACGAGTTGTTGGTCAGGATGAGGCTGTTAAAGCTGTTGCAAGGGCTATAAGACGAG
GAAGAGTTGGTCTCAAAGACCCGAAAAGACCAATTGGTTCGTTTATCTTCCTTGGACCTACTGGTGTAGGTAAAACAGAG
CTTGCAAGGGCTTTAGCAGAAGCACTGTTTGGCACAGAGGATGCTATGATAAGAATCGACATGTCGGAGTATATGGAAAA
GTTCAATGTGTCAAAGCTTATTGGTTCGCCTCCAGGTTATGTCGGATATGAAGAAGGTGGCCAGCTTACCGAAAAGGTCA
GAAGAAGACCGTACTCTGTTGTGCTGTTCGATGAGATAGAAAAAGCGCACCCTGATGTTTTCAACCTGCTTTTGCAGATA
CTTGACGATGGAAGGCTCACAGACTCTCAGGGAAGAACGGTAAGCTTTAGAAACACTGTTATCATCATGACATCTAACAT
AGGAGCAAACCTCATCACAAACCCTAAAAAGTTAGGATTTTCAACTTCAGAAGATGAAAAACAAAGAACATATGAAAGAA
TAAAGGAAAATGTCATGGCAGAGCTTAAGAAAACTTTCAGACCAGAGTTTTTGAACAGAATTGATGAAATTATAGTCTTC
CATCCGCTTGATGAAGAGGATGTTAAAAAGATTGTAGAGATAATGCTTAAAAACTTGCAGGAAAGGATAAAAGCAAGCGA
GTACTATGCAGAGTTTACTTCTTCCTTAGTTGAAGCAATTGCTAAAAAAGGATTTGACCCTGTATTTGGTGCAAGACCGT
TAAAGCGAGCAATCCAGAGTATGGTAGAAGACAAGATTTCAGAGGCTATCTTGGAAGGGAAGATAAAACAGGGCGATGAA
TTTATAGTAGACTTTATTGATGGAAATACAGAGATAATCAAAAAAGAAAAGGCATCTACATCTTCATCTGAAATGGCTCA
GTCACAGTAA

Protein sequence :
MFQGRFTERAEKAIMLAQQAAAELGHNYVGTEHLLLGLIREGGGIAARVLQSQGVTEEKVIDEIEELIGRGDYQLPQPPT
GFTPRTKRVFEIAFMEARRLGSSYISTEHILLAIMREGESVAVRILMDLGVDPQRLFEEIMKLLNEDAKNVGGVSPQQQI
NFQTQNTPTLNQFSRDLTQLALEGKIDPVIGREKEIERVIQILSRRTKNNPCLIGEPGVGKTAIVEGLAQKIVEGNVPEL
LRNKRVVALDLSAMVAGSKFRGEFEERLKKAMEEVRKAGNVILFIDEMHTIIGAGAAEGAIDASNILKPALARGEIQVIG
ATTLDEYRKHIEKDAALERRFQPILVGEPTPEEAIQILKGLRDKYEAHHGVKITDEAIKAAVELSTKYITDRYLPDKAID
LIDEAASRVRLRMYTLPPHVKEFEEKIEKLEKEKEEAIRLQEYEKAAKIRDEIMKLRQELEKIKNSWTNDQQKTQPIVTE
DDIAYIVSSWTGIPVNKLTEDESERLLKLEEVLHRRVVGQDEAVKAVARAIRRGRVGLKDPKRPIGSFIFLGPTGVGKTE
LARALAEALFGTEDAMIRIDMSEYMEKFNVSKLIGSPPGYVGYEEGGQLTEKVRRRPYSVVLFDEIEKAHPDVFNLLLQI
LDDGRLTDSQGRTVSFRNTVIIMTSNIGANLITNPKKLGFSTSEDEKQRTYERIKENVMAELKKTFRPEFLNRIDEIIVF
HPLDEEDVKKIVEIMLKNLQERIKASEYYAEFTSSLVEAIAKKGFDPVFGARPLKRAIQSMVEDKISEAILEGKIKQGDE
FIVDFIDGNTEIIKKEKASTSSSEMAQSQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 54
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-94 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Athe_1825 YP_002573691.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 0.0 61
Athe_1825 YP_002573691.1 ATPase AAA-2 domain-containing protein VFG0080 Protein 8e-152 53