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Name : guaA (Athe_1432) Accession : YP_002573303.1 Strain : Caldicellulosiruptor bescii DSM 6725 Genome accession: NC_012034 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 1511882 - 1513417 bp Length : 1536 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : TTGCAACATGAGATTGTAATAGTTCTGGACTTTGGTGGTCAATATAACCAGCTTATTGCAAGAAGAGTAAGAGAATGCGG AGTATACTGTGAAATTTGGCCATACGACACACCTCTTGAAAAGATAATTAGTAAAAATCCAAAAGGAATTATATTTACAG GTGGACCATCAAGTGTATACGAGCCAAACGCTCCTATGATTGACAAAGAACTGTTCGAAAAGGGTATTCCAATACTTGGG ATATGTTATGGAAACCAGTTAATTGCTCATATTATGGGAGGAAAAGTGTCAAGGGCGCTATTTAGAGAGTATGGAAAGAC GCATATAAAATACGATATTTCTTCTCCTCTTTTCAGCGGAATACCTGAACATTCTGTGTGTTGGATGAGCCACACAGATT TTGTAGAAAAACTTCCAGAGGGGTTTAAAGCTTTGGCATCCACCGAAAATTGTTCTATTGCAGCATTTGGGGATGATACC AGAAAAATATATGGTGTTCAGTTTCATCCTGAGGTTGTCCATACCGAATATGGTCAGAAAATTATAGAAAACTTTTTATT TAACATTTGTAATTGCCATGGTGATTGGAAAACCTCATCATTTATTGAGGAAAAGGTAAATGAGATAAAAGATATTGTAG GCAACCAAAAAGTGGTATGTGCCCTTTCAGGTGGTGTTGATTCTTCTGTTGCAGCAGTCCTTGTTCACAAAGCTATAGGG AAAAATCTTTATTGCATATTTGTTGACCATGGTCTTTTGAGAAAGGGCGAAGCTGAAGAAGTTGTGAGTGTTTTTAAAGA TAAATTTGACATGAATGTAATCAAGGTTGATGCAAAAGACAGGTTTTTGGAGGCTTTAAAAGGTGTTACTGATCCAGAAG AAAAACGAAAGATAATTGGAAGGGAATTTATCAGAGTATTTGAAGAAGAAGCAGAAAAGCTTGGAGATATAAAGTTTTTG GTGCAGGGTACTATTTATCCTGACGTGGTTGAAAGCGGGGTTGGCAAGGCTGCAACTATAAAAAGCCACCACAATGTTGG TGGTCTTCCTGAAAAAATAAAATTCAAACAAATAATTGAACCTCTCAGAGATTTGTTTAAAGACGAAGTGAGAAGGGTAG GAATAGAATTAGGAATACCTGAAAAGATTGTCAAAAGGCAGCCTTTTCCTGGACCTGGTCTTGCAATAAGAATAATTGGA GAGGTTACAGAGGAAAAATTGGACATACTGCGCGAGGTTGATTGGATCTTTAGAAAAGAGATTGAACAGAGCGGCCTTGA CAATGAAATATGGCAGTACTTTGCAGTTTTAACTAATATGAAAAGTGTTGGTGTAATGGGTGATGAGAGAACATATGATT ACACAGTTGCTCTAAGAGCTGTTACAAGTATTGATGGAATGACCGCTGACTGGGCTAAAATACCTTATGAGATTTTAGAG AGAGTTTCAAATGAGATTGTAAACAGTGTGAAAAAGGTCAACAGGGTGGTGTATGACATCACTTCAAAACCTCCTGCTAC AATTGAATGGGAATAA Protein sequence : MQHEIVIVLDFGGQYNQLIARRVRECGVYCEIWPYDTPLEKIISKNPKGIIFTGGPSSVYEPNAPMIDKELFEKGIPILG ICYGNQLIAHIMGGKVSRALFREYGKTHIKYDISSPLFSGIPEHSVCWMSHTDFVEKLPEGFKALASTENCSIAAFGDDT RKIYGVQFHPEVVHTEYGQKIIENFLFNICNCHGDWKTSSFIEEKVNEIKDIVGNQKVVCALSGGVDSSVAAVLVHKAIG KNLYCIFVDHGLLRKGEAEEVVSVFKDKFDMNVIKVDAKDRFLEALKGVTDPEEKRKIIGREFIRVFEEEAEKLGDIKFL VQGTIYPDVVESGVGKAATIKSHHNVGGLPEKIKFKQIIEPLRDLFKDEVRRVGIELGIPEKIVKRQPFPGPGLAIRIIG EVTEEKLDILREVDWIFRKEIEQSGLDNEIWQYFAVLTNMKSVGVMGDERTYDYTVALRAVTSIDGMTADWAKIPYEILE RVSNEIVNSVKKVNRVVYDITSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 5e-155 | 60 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 5e-155 | 60 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-155 | 60 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-132 | 52 |
