Gene Information

Name : Athe_1266 (Athe_1266)
Accession : YP_002573139.1
Strain : Caldicellulosiruptor bescii DSM 6725
Genome accession: NC_012034
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1356737 - 1358494 bp
Length : 1758 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; KEGG: csc:Csac_1831 pyruvate kinase

DNA sequence :
TTGAGAAAAACAAAAATAATTTGTACATTAGGTCCAGCGACCGACTCAGAGGAGATAATAAGAAAACTTGTTGAAAATGG
GATGGATGTTGTGAGGTTAAATTTTTCTCATGGTACTCATGAAGAGCATAAGAAAAAGATTGACATGGTAAAAAAAATAA
GAGAAGAATTTGACAAGCCTATTCCCATTTTGCTTGACACAAAAGGACCAGAGATAAGAATAGGTTTTTTTAAAGATGGC
AAAGTAGAATTGAAAGAAGGTCAGAAATTTGTTCTGACTGTGGAAGAAATCTTGGGAAATGAAGAGATTGTTAGTATCAC
TTATAAAGAACTTGTTGAGGATGTAAAACCAGGTGATAAAATCCTGATAGATGATGGACTTATTGAGCTTATTGTTGAGG
ACAAGACAGAAAAGAATATAATCTGCAAGGTAAAAAATGGAGGAGTCTTAACCAACCAGAAAGGGGTAAACGTACCGGGT
ATACCCATTAGGCTTCCTGCACTTACCCAGAAGGATAAAGAGGATATTCTGTTTGGGATAGAAAATGATGTAGATTTTAT
TGCAGCTTCATTTATAAGAAAGGCAAGTGACGTTGTTGAAATTAGAGAGTTTCTGAACAAAAATGGTGGAAAGGACATTT
TAATAATTGCCAAGATAGAAACTCAAGAAGGTGTTGCAAACTGCGACGAAATAATAAGAGTTGCAGATGGAATTATGGTT
GCAAGAGGAGATTTAGGGGTGGAACTTCCTTTTGAGGAAGTCCCCCTTGTTCAAAAAATGCTCATTGAAAAATGCTACAA
AGCAGGAAAGCCTGTCATAACAGCAACACAGATGCTTGAATCTATGATACGAAATCCAAGACCTACCAGGGCAGAGGTTA
GCGATATTGCCAATGCCATATTTGATGGAACTTCTGCAATAATGCTCTCTGGCGAAACGGCAATGGGCAAATATCCTGTT
GAAAGTGTTGCTACAATGGCAAAGATTGCCGAAAGAGTGGAAAATCAGATTGATTATATCAAGAGATTTCAATCTCAGGT
ATTTGATATGCCAGTTAATGTGACAAATGCTATTTCGCACGCAACTTGTACAACTGCACATGACCTTGGTGCAAAAGCTA
TTATAACTGTAACAAAGTCAGGTAACACTGCAAGAATGGTTTCAAAATTCAGACCTGCTTGTCCGATTATTGCAACCACA
CCTTGTGAGAAGGTTAGGAGACAGCTGAATCTGTCATGGGGTGTGTATCCATTTTTGGCAGAATACAAAAGTTCGACCGA
TGATATATTTGACCATGCTGTTGAGATAGCTGTAAAATCCAAGATTGTAAAAAACGGAGATTTAGTCGTCATTACTGCTG
GAGTTCCTGTTGGCGTGAGTGGAACAACAAATATACTTAAAGTTCATGTCGTTGGACATGTTTTGGTTGAAGGGCGAGGT
TGGGGAAGCGGAAAGGTAACAAGCAGGGTATGCGTTGTTAAAAGCATTAATGAACTTAAGCAGAATTTTGAAGATGGAGA
TATAATAGTTACAAGCCAGACAAATAATGAGTTTATACCTTATATGAAAAGGGCTTCGGGAATTATCACAGAAGAGGGTG
GACAGAACTCTCATGCAGTAATTGTAGGTGCTGCACTTGATATCCCTGTAATAACAGATGCTAAAAATGCATTGGAGATA
TTAAAAACAGGGATTGTAGTTACAATTGATACTCAAAAAGGAATAGTATTTAGTGGAGAGCAGAAGATAGAAGAATAA

Protein sequence :
MRKTKIICTLGPATDSEEIIRKLVENGMDVVRLNFSHGTHEEHKKKIDMVKKIREEFDKPIPILLDTKGPEIRIGFFKDG
KVELKEGQKFVLTVEEILGNEEIVSITYKELVEDVKPGDKILIDDGLIELIVEDKTEKNIICKVKNGGVLTNQKGVNVPG
IPIRLPALTQKDKEDILFGIENDVDFIAASFIRKASDVVEIREFLNKNGGKDILIIAKIETQEGVANCDEIIRVADGIMV
ARGDLGVELPFEEVPLVQKMLIEKCYKAGKPVITATQMLESMIRNPRPTRAEVSDIANAIFDGTSAIMLSGETAMGKYPV
ESVATMAKIAERVENQIDYIKRFQSQVFDMPVNVTNAISHATCTTAHDLGAKAIITVTKSGNTARMVSKFRPACPIIATT
PCEKVRRQLNLSWGVYPFLAEYKSSTDDIFDHAVEIAVKSKIVKNGDLVVITAGVPVGVSGTTNILKVHVVGHVLVEGRG
WGSGKVTSRVCVVKSINELKQNFEDGDIIVTSQTNNEFIPYMKRASGIITEEGGQNSHAVIVGAALDIPVITDAKNALEI
LKTGIVVTIDTQKGIVFSGEQKIEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-105 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-105 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Athe_1266 YP_002573139.1 pyruvate kinase VFG0479 Protein 3e-106 51