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Name : leuS (Athe_1254) Accession : YP_002573127.1 Strain : Caldicellulosiruptor bescii DSM 6725 Genome accession: NC_012034 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 1342969 - 1345422 bp Length : 2454 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGAATATAATTTTAAAGAAATTGAAAAGAAATGGCAGCAAAAATGGTTTTCACAGAACAAATACAAAGTATCAGAGGA TAGTTCAAAACCCAAATATTATGTCCTTGAGATGTTTCCATATCCTTCAGGAAAACTTCATATGGGACATGTGAGGAACT ATTCGATTGGTGATGTATTTGCTCGATTTATGAGATTAAAAGGCTACAACGTTTTGCACCCGATGGGCTGGGATGCTTTT GGATTGCCAGCTGAAAATGCTGCTATAAAGCATGGGATTCATCCTTCTGACTGGACGTGGTCAAACATTGAAAATATGAA AAGGCAACTTATGGAACTTGGAATTAGCTATGATTGGGATAGAGAAGTAGCCACATGCCATCCAGATTATTATAAATGGA CTCAGTGGATGTTCTTGCAGTTTTATAAAGCTGGGCTTGCTTATAGAAAGAGATCATATGTAAACTGGTGCCCATCGTGT GAGACAGTGCTTGCAAATGAACAGGTTGTAAATGGTAGATGTGAAAGATGTAAATCACTTGTTGGTAAAAAAGATTTAGA GCAGTGGTTTTTCAGAATTACCAATTATGCAGAAAGACTTCTTCGTGATATAGAAAAGCTTGATGGGTGGCCAGAAAAGG TAAAGATAATGCAAAAGAACTGGATAGGAAGAAGTGAAGGTGCAGAGATTGAGTTTGAAATTGAGGGTTTGGGTAAAAAA ATAAAAGTATTTACAACAAGACCTGATACTCTTTTTGGCGTCACATACCTTGTTTTGGCTCCAGAACATCCTTTAACAAA GGAGATAATAGCAGGGAAACCTCAAGAGAAAGAATGTCTTGAGTTTATCGAAAAGATGCAATATCTAAATGAGATTGAAA GAACTTCTACAGAAACAGAAAAAGAAGGAAGGTTTACGGGTGGATATGCTATTCATCCTCTAACAGGTGAAAGAGTGCCA ATATACATTGCAAATTATGTACTGGTTGATTATGGAACAGGGGCTGTAATGGGTGTCCCAGCCCATGACCAGAGGGATTT TGAGTTTGCCAAAAAATATAATCTTTCAATTAAAGTTGTAATAAAAGGTGAAGGTATTGACATTGAAAATCTTCAGAGTG CTTATGAAGACGAAGGTGTTTTGATTAATTCTGGAATTTTTAATGGGCTTAATAACAAAGAAGCTATGAAAAAGATAACA CAGTACCTGGAACAAAAAGGTGTTGGCAGGGCGTGTGTCACATATAAACTCAGAGACTGGTTAATATCCAGGCAGCGTTA TTGGGGAGCTCCAATTCCCATTGTATATTGTGAAGAATGTGGAATTGTTCCTGTACCAGAGGAAGATTTGCCTGTTTTAT TACCTTACAATGTTGAATTTAAACCAACAGGTCAGTCACCACTTTCTTATTGTGAAGAGTTTGTCAACACTACATGCCCG AAGTGCGGGAAGCCTGCAAAGAGAGAAACTGATACAATGGACACATTTATATGTTCATCGTGGTATTATTTTAGATACAC AGACCCCAAAAATGATAAAAAACCTTTTGAAAAATCGCTTGTTTCTTACTGGCTTCCTGTTGACCAGTATATTGGCGGGG TTGAACATGCTATATTGCATCTTCTGTATTCGAGGTTCTTTACAAAGGTGCTATATGACCTTGGCTATGTACCTTTTGAA GAGCCTTTCAAGAACCTCTTGACCCAAGGCATGGTGTTAAAAGATGGAGCAAAGATGTCAAAATCACTGGGAAATATAGT CAGTCCTGAAGACATAGTAGAAAGGTATGGAGCTGACACAGCAAGGTTGTTTATACTCTTTGCTGCACCACCAGAGAGAG ATTTGGAGTGGTCAGACCAAGGGGTTGAAGGATGTTTTAGGTTTTTAAATAGGCTGTGGAGACTTTATATAGAACTTAAA GACAAACTTGCAGATGATAATCTTATTGGTGAGTCTGAACTTGACGATGAACTAAGATATAGATTAAATTATACAATTAA AAAGGTTACAGAGGATATAGCAGAGAGGTTTAATTTTAATACTGCTATCAGTACTATCATGGAGCTTTTGAATTTCTTGT ATGAGTACAAAGAATGTGGCAAATTAAATAAAGATTTAATTAAAGATACACTCAGGAATTTATTGATATTGATTTATCCA TTTACGCCTCATATTGCATGTGAGCTATGGGAGATTATGGGGTATGGTAATGATATTGAAGAGGTAAACTGGCCTCAGTA CAATGAAGCTGCTCTTGTTCGAAAGAACGTAGAGATTGCTATTCAGATAAATGGCAAGGTAAGGTCAAGGATGAACATCT CTGTGGATATGACAGAAGAAGAAGTGAAACAGGCAGTTATATGTGACGAGAAACTTAAAGCTCTTTTGAATGGGAAAGAA ATAGTCAAGTTTGTGTATGTGAAAAATAGACTTGTTAACATTGTGGTGAAATAA Protein sequence : MEYNFKEIEKKWQQKWFSQNKYKVSEDSSKPKYYVLEMFPYPSGKLHMGHVRNYSIGDVFARFMRLKGYNVLHPMGWDAF GLPAENAAIKHGIHPSDWTWSNIENMKRQLMELGISYDWDREVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSC ETVLANEQVVNGRCERCKSLVGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGAEIEFEIEGLGKK IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQEKECLEFIEKMQYLNEIERTSTETEKEGRFTGGYAIHPLTGERVP IYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLSIKVVIKGEGIDIENLQSAYEDEGVLINSGIFNGLNNKEAMKKIT QYLEQKGVGRACVTYKLRDWLISRQRYWGAPIPIVYCEECGIVPVPEEDLPVLLPYNVEFKPTGQSPLSYCEEFVNTTCP KCGKPAKRETDTMDTFICSSWYYFRYTDPKNDKKPFEKSLVSYWLPVDQYIGGVEHAILHLLYSRFFTKVLYDLGYVPFE EPFKNLLTQGMVLKDGAKMSKSLGNIVSPEDIVERYGADTARLFILFAAPPERDLEWSDQGVEGCFRFLNRLWRLYIELK DKLADDNLIGESELDDELRYRLNYTIKKVTEDIAERFNFNTAISTIMELLNFLYEYKECGKLNKDLIKDTLRNLLILIYP FTPHIACELWEIMGYGNDIEEVNWPQYNEAALVRKNVEIAIQINGKVRSRMNISVDMTEEEVKQAVICDEKLKALLNGKE IVKFVYVKNRLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-173 | 45 |
