Gene Information

Name : Chy400_0475 (Chy400_0475)
Accession : YP_002568238.1
Strain : Chloroflexus sp. Y-400-fl
Genome accession: NC_012032
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 573333 - 574604 bp
Length : 1272 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGACATTAAACTCATTCGTGAACAACCCGATGAAGTAAAACGCCGGCTCGCTCGTTGTGGGGTTGATGGGGCAGT
CGTCGATCAGGTGCTGGCTTTTGATGAACAACGCCGACGCCTGATTTATGAGGTGGAGACGCGCAAAGCTGAGCGTAATA
CCGTCTCGAAGCAGATTGGTGCGATGAAAGACCCGGCTGAGCGGCAGGCAAAGATAGATGCGATGCGCCAGTTGGGTGAT
GAAATCGCCGCGCTCGACCGGCAACTGGCCGAGGTGGAAGAGCAGCAGCGGGCAGTGATGCTCGAAATTCGCAATCTGCC
CCATCCTGATGTTCCCGATGGGGTTGATGATCGCGACAATGTGGTGATCTATCAGGAGGGTGAAGAGCGGCAGTTGCCCT
TCCCGGCCCGTCCGCACTGGGAATTGGGTGAAGCGTTAGGCATCATCGATTTTGAACGCGGGGTGAAGCTGGCCGGTTCC
CGTTTCTACGTGATGCGTGGGGCAGGCGCCCGCCTTCAGCGCGCTGTTATTCAGTGGTTGATCGATCTGCACCTGGAACA
GGGTTACCAGGAAGTGTACACACCCTTTGTGGTCAAAGAGTCGGTGTTGTGGGCATCAGGTCAGTTGCCGAAGTTCCGCG
ATAACCTCTACCGCGACGAAGAGTCGGGTTTATGGCTGGTGCCAACGGCAGAAGTTCCGTTGACCAGTCTCTACGCCGAT
GAAATCCTCGACGCGAGTCAGTTGCCGATCTATCACGTTGCCTATACGCCCTGTTTCCGCAAAGAGCAGCTTAGCGCCGG
GCGTGATGTGCGTGGTATCAAGCGCGGCCATCAGTTCGACAAGGTTGAGATGTATATGTTCGTGACGCCTGATCAGAGCT
ATCAGGCGCTCGAAAAACTGCGCCGCGATGCTGAAGAGTGTGCCCGCCGGTTAGGATTGCCGTTCCGCACTAAACTGCTC
TGTACCGGCGATCTCGGTTTTGGTTCAACCAAGACCTACGACATTGAAGTTTGGGCGCCGGGTGTGGGCGAATGGCTTGA
AGTCAGTTCGTGCTCGAATGTGGAAGCATTTCAGGCCCGACGCGCCAATTTGCGCTACCGACCTGAACCGGGAGCAAAGC
CTGAGTTTTTACACACGCTGAACGGTTCAGGATTGGGGTTACCGCGCACAATCATCGCGATTATGGAGAATTATCAGCAG
GAAGACGGAAGTATCCTGATACCTGAGGTGTTACGGCCATATATGGGTGGTATGGAACGGATCGGGCCATAA

Protein sequence :
MLDIKLIREQPDEVKRRLARCGVDGAVVDQVLAFDEQRRRLIYEVETRKAERNTVSKQIGAMKDPAERQAKIDAMRQLGD
EIAALDRQLAEVEEQQRAVMLEIRNLPHPDVPDGVDDRDNVVIYQEGEERQLPFPARPHWELGEALGIIDFERGVKLAGS
RFYVMRGAGARLQRAVIQWLIDLHLEQGYQEVYTPFVVKESVLWASGQLPKFRDNLYRDEESGLWLVPTAEVPLTSLYAD
EILDASQLPIYHVAYTPCFRKEQLSAGRDVRGIKRGHQFDKVEMYMFVTPDQSYQALEKLRRDAEECARRLGLPFRTKLL
CTGDLGFGSTKTYDIEVWAPGVGEWLEVSSCSNVEAFQARRANLRYRPEPGAKPEFLHTLNGSGLGLPRTIIAIMENYQQ
EDGSILIPEVLRPYMGGMERIGP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-98 50