Gene Information

Name : Chy400_1964 (Chy400_1964)
Accession : YP_002569695.1
Strain : Chloroflexus sp. Y-400-fl
Genome accession: NC_012032
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 2493120 - 2496254 bp
Length : 3135 bp
Strand : +
Note : KEGG: cau:Caur_1816 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases

DNA sequence :
ATGGCGCATTTGACCGAATCAAACATCGAGACCGTCGCCCTTGACTGGTTGAAATCGCTGGGTTGGCAGGTCGCGCACGG
TCCTGGTATCGCTCCTGGCATGTCGGCAGCCGAACGTCAAAACTACGGCGAGGTCGTGCTCGAGCAGCGCCTGCGCGACG
CTCTTGCACGTCTCAACCCCGACCTGCCAACCGAGGCGCTGGACGACGCCTTCCGCAAACTGACTCAACCCGAAGGGGCT
GATCTTCTCCAGCGCAACCGCGTCGTTCACCTCATGCTGGCGAACGGCGTGACGGTGGAATACCGTCATCCCGACGGCGG
TATTCGCGGCACACAGGTGCGTGTGATAGATTTCGACGACCCCGCCAACAACAACTGGCTGGCGGTGAACCAGTTTAGCA
TTGAGGAGAACAAGCACAACCGCCGCGCCGACGTGGTGCTGTTCGTCAACGGTCTGCCCCTCGCGATCATCGAACTCAAA
AACGCAGCCGACGAGCACGCAACCATCTGGAGTGCATTCCAGCAATTGCAAACCTACCAGGTAGAGATCCCATCCTTGTT
TGTCTTCAACGAGACGTTAGTTATCTCTGATGGTCTCGAAGCGCGCATTGGCACACTGGGTGCTGGTCGCGAGTGGTTTA
AACCCTGGCGCACCATCTCCGGCATGCAGGTAGAGGATGTTGGTGTACCACAGCTAGAGGTTGTGCTCAAGGGTGTGTTC
GAGAAAAATCGCTTTCTTACTCTCATACGTGACTTTATCGTGTTTGAGGACGATGGTAGTGGACGGTTAGTGAAGAAGAT
GGCTGGTTACCACCAGTTTCATGCTGTACTGGTAGCGGTGAAGGAAACCCTACGCGCCAGCGCAGTTGTTTCATCCAACC
GTATGGCGGAGTCGGGTGGCGTCTATGAAGCAGGACGCGAACCTGGCGGTAAGCCTGGTGATCGACGTATCGGTGTTGTC
TGGCACACGCAAGGTTCGGGAAAGAGCCTGACGATGGTGTTCTACGCGGGGTGCATCATTCGCAAACCAGCTATGGAGAA
CCCTACCATCGTTGTGCTTACCGACCGTAATGATCTTGACGACCAGCTCTTCAACACCTTCTCACGCTGTCAGGATTTAC
TGCGCCAGCCGCCCGTGCAAGCTGAAAGTCGTGTACACCTACGCCAGCTCCTAAGCGTGCAGTCAGGCGGTATCGTTTTT
ACCACTATTCAGAAATTTCTACCCGAAGAGAAGGGCGACCGTCATCCAGTATTGTCCAACCGTCGGAACATCGTCGTGAT
CACTGACGAGGCACACCGCAGCCAGTACGACTTCATTGACGGTTTTGCCCGCCATATGCGCGATGCACTACCTCAGGCAT
CCTTTATTGGTTTCACTGGCACGCCGATTGAGAAGGCGGATGCCGATACACGAGCAGTTTTTGGAGATTACATCTCAATC
TATGATATTCAGCGTGCGGTGGAAGATGGTGCGACCGTATCGATTTATTATGAGGCACGGCTAGCAAAACTCGATCTTCC
TGACGAACTCAAGCCAAAGATTGACGATGAGTTTGAGGAGATTACAGAAGGTGAGGAAGTTGAGCGTAAAGAAAAGCTCA
AAACCAAATGGGCGCAGCTTGAATCCATTGTCGGCACTGAACAACGGCTGAGACTGATTGCCAACGATATTATCGAGCAT
TTTGAGCGGAGACTGGAGGCAATCGAAGGTAAAGGCATGGTTGTCTGCATGAGCCGGCGCATCTGTGTTGAGCTGTATAA
CATCATTTGCACTCTTCGTCCCAACTGGCATCACGAAGACGACGACAAAGGTGTAATAAAGGTAGTGATGACCGGTTCTG
CCTCCGACCCGGTAGACTGGCAGCCGCATATTCGCAATAAACAACGCCGCGAACTGCTGGCGAAGCGCTTTCGTGATCCG
AACGATCCGCTTAAATTGGTCATCGTGCGTGATATGTGGCTCACCGGATTTGATTGTCCGAGTCTACACACGATGTACCT
GGACAAGCCGATGCGCGGCCACGGGTTAATGCAGGCAATTGCCAGGGTCAATCGCGTCTTTCGCGATAAGCCGGGTGGTC
TGGTGGTGGACTATCTGGGCCTTGCCCACGAATTGAAGGCTGCACTGGCGGTTTACACTGAAAGCGGTGGTACTGGTAAA
ACCACTATTGACCAGGAAGAGACTGTTGCGTTGATGCAAGAGAAGTACGAAATCTGCTGTGGAATCCTGCACGGCTTCGA
TTGGTCGGATTGGGCAAGTGGTGATGCACATGCACGCATTGGACTTTTACCTGCAGCTCAAGAACACGTGCTGGCACGCG
TGAAAGGAAAGGAACGATTTGTTCAGGCGGTGCGTGATTTGACAAAAGCCTTTGCCCTTGCAGTGCCGCATGAAAAAGCG
CTTGAGATTCGTGATGATGTGGCATTTTTTCAGGCGCTCTCTGCGGCGCTGACCAAACGCGCACCCGGCGATGTAAGAAC
TGAAGAGCAGCTAGATCATGCCATTCGGAGGATTATTGCGCAGGTAATTGCGCCTGAAGGCGTGGAGGATATTTTTGCTG
CGGCAGGGCTGAAAAAGCCGGATATCTCCATCCTCTCCGATGAATTCCTGGCTGAAGTGCGTGGTATGCCGCACAAGAAT
CTGGCAGTTGAAGTTCTTCAGAAACTGCTTAACGGTGAAATTAAGAGGCGTAGCCACAAAAATATCGTTCAGGCACGCTC
ATTCGCTGAACTGTTACAGCAAGCCCTTCACCGTTACCAGAATCGTGCAATCGAAGCAGCACAGGTGATCGAAGAATTGA
TAACTTTGGCGAAGGAAATGCGTGAAGCCGACCGGCGGGGTGAAGTATTGGGCCTTTCGGAGGAGGAGCTGGCGTTTTAC
GATGCGCTTGAAACAAATGATAGTGCTGTGGCTGTGTTGGGTGATCAGACTCTACGCACCATTGCCCGTGAACTCGTCGA
GACCGTGCGTAACAGTATCAGTATTGATTGGGCACAGCGGGAAGATGTACGGGCGAATCTACGCAGATTGGTTAAGCGCA
TTCTTCGCAAGCACGGCTATCCACCAGACAAGCAGGAGAAAGCTACGCAGACTGTATTGGAACAGGCGGAAGTGCTTTCA
GCAGAATGGGCCTAA

Protein sequence :
MAHLTESNIETVALDWLKSLGWQVAHGPGIAPGMSAAERQNYGEVVLEQRLRDALARLNPDLPTEALDDAFRKLTQPEGA
DLLQRNRVVHLMLANGVTVEYRHPDGGIRGTQVRVIDFDDPANNNWLAVNQFSIEENKHNRRADVVLFVNGLPLAIIELK
NAADEHATIWSAFQQLQTYQVEIPSLFVFNETLVISDGLEARIGTLGAGREWFKPWRTISGMQVEDVGVPQLEVVLKGVF
EKNRFLTLIRDFIVFEDDGSGRLVKKMAGYHQFHAVLVAVKETLRASAVVSSNRMAESGGVYEAGREPGGKPGDRRIGVV
WHTQGSGKSLTMVFYAGCIIRKPAMENPTIVVLTDRNDLDDQLFNTFSRCQDLLRQPPVQAESRVHLRQLLSVQSGGIVF
TTIQKFLPEEKGDRHPVLSNRRNIVVITDEAHRSQYDFIDGFARHMRDALPQASFIGFTGTPIEKADADTRAVFGDYISI
YDIQRAVEDGATVSIYYEARLAKLDLPDELKPKIDDEFEEITEGEEVERKEKLKTKWAQLESIVGTEQRLRLIANDIIEH
FERRLEAIEGKGMVVCMSRRICVELYNIICTLRPNWHHEDDDKGVIKVVMTGSASDPVDWQPHIRNKQRRELLAKRFRDP
NDPLKLVIVRDMWLTGFDCPSLHTMYLDKPMRGHGLMQAIARVNRVFRDKPGGLVVDYLGLAHELKAALAVYTESGGTGK
TTIDQEETVALMQEKYEICCGILHGFDWSDWASGDAHARIGLLPAAQEHVLARVKGKERFVQAVRDLTKAFALAVPHEKA
LEIRDDVAFFQALSAALTKRAPGDVRTEEQLDHAIRRIIAQVIAPEGVEDIFAAAGLKKPDISILSDEFLAEVRGMPHKN
LAVEVLQKLLNGEIKRRSHKNIVQARSFAELLQQALHRYQNRAIEAAQVIEELITLAKEMREADRRGEVLGLSEEELAFY
DALETNDSAVAVLGDQTLRTIARELVETVRNSISIDWAQREDVRANLRRLVKRILRKHGYPPDKQEKATQTVLEQAEVLS
AEWA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 50
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 45
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 45
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 45