Gene Information

Name : Hlac_2073 (Hlac_2073)
Accession : YP_002566721.1
Strain :
Genome accession: NC_012029
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2061563 - 2062933 bp
Length : 1371 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGTCTCGACAGTTCGTCCGGGAGAACCCCGAGGTCGTTCGCGAGGCGCTCGACAACAAGGGCGTCGACGTGGACCT
CGACCGGATACTCGACGTTGACGAGGAGTGGCGGGAGCTGAAGAGCCGTGGCGACGATTTGCGCCACGAGCGCAACGAGG
TCTCCTCGACGATCGGCGAGCTGAAACAGGCCGGCGAGGAGGAGGCGGCCCAAGAGGCGATCGAGCGCTCACAGGAGGTC
AAGTCGGAGCTGCAGGAGATCGAAGAGCGCGCCGACGAGCTGGAGGCCGAACTGGAGGAGTCCCTGCTCGAACTCCCCCA
GATCCCCCACGAGTCGGTGCCGGTCGGGGCCGACGAGTCGGAGAACGTCGAGCGACGCCGCGAGGGGTTCGACGACCTGC
GCGAGGTTCCCGACAACGTGGAGCCCCACTACGATCTGGGCGAGGAGCTGGAGATCCTCGACTTCGAGCGCGGCGCGAAA
GTCGCCGGCGGCGGCTTCTACGTCGCGAAGGGCGACGGCGCCCGGCTGGAGCATGCGCTGATCCAGTTCATGCTCGACGT
GCATCGCGAGCAGGATTACCGTGACGTGTTCCCGCCGATCGCGGTCAACTCCACGTCGATGCGCGGCACCGGCCAGCTCC
CGAAGTTCACCGAGGACGCCTACCGGATCGAGGGGACCAACGAGGACGCGTACGACGACGACGACCTCTGGCTGCTCCCG
ACCGCGGAGGTGCCCGTCACGAACCTCCACCGCGACGAGATCCTGCTCGGCGAGGACCTCCCGCTCAAGTACCAGGCGTA
CACGCCGAACTTCCGGCAGGAGGCGGGTGAGCACGGCACCGAAACGCGCGGGATCGTCCGCGTCCACCAGTTCAACAAGG
TGGAGATGGTGAACTTCGTCCGGCCCGAGGAGAGCCACGAGCGCTTCGAGGGCCTCGTCGATGAGGCCGAGGAGGTGCTT
CGCCGCCTCGAACTTCCCTACCGCATCCTGGAGATGTGTACCGGCGATCTGGGGTTCACGCAGGCGAAGAAGTACGACCT
TGAAGTCTGGGCGCCGGCCGACGACATGGACGAGGGCCCCGCAGAGGGCGGCCGCTGGCTGGAGGTCTCCTCCGTCTCGA
ACTTCGAGGAATTCCAGGCGCGCCGTGCCGGGATCCGGTACCGCGAGGAGCACCACGAGTCCGCGGAGTTCCTCCACACC
CTGAACGGTTCGGGGCTCGCCGTCCCGCGGATCGTCGTCGCGATCTTGGAGTACTACCAGAACGACGACGGCACCGTCAC
CGTCCCCGAGGCGCTGCGCCCGTACATGGGCGGCACAGAGGTGATCGAGGGTCACGACGCGGTCGGCGAGACGAAGCTCG
GCGGGGAGTAG

Protein sequence :
MLSRQFVRENPEVVREALDNKGVDVDLDRILDVDEEWRELKSRGDDLRHERNEVSSTIGELKQAGEEEAAQEAIERSQEV
KSELQEIEERADELEAELEESLLELPQIPHESVPVGADESENVERRREGFDDLREVPDNVEPHYDLGEELEILDFERGAK
VAGGGFYVAKGDGARLEHALIQFMLDVHREQDYRDVFPPIAVNSTSMRGTGQLPKFTEDAYRIEGTNEDAYDDDDLWLLP
TAEVPVTNLHRDEILLGEDLPLKYQAYTPNFRQEAGEHGTETRGIVRVHQFNKVEMVNFVRPEESHERFEGLVDEAEEVL
RRLELPYRILEMCTGDLGFTQAKKYDLEVWAPADDMDEGPAEGGRWLEVSSVSNFEEFQARRAGIRYREEHHESAEFLHT
LNGSGLAVPRIVVAILEYYQNDDGTVTVPEALRPYMGGTEVIEGHDAVGETKLGGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-78 56