Gene Information

Name : hemC (AMF_523)
Accession : YP_002563632.1
Strain : Anaplasma marginale Florida
Genome accession: NC_012026
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 637252 - 638163 bp
Length : 912 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGTATGCTCCTGTGGTCAGGCTGGGAACAAGAGGAAGCACGCTGGCACTAATACAAGCAGAGGAGGTCAAAGCCGCAAT
TGCAGCCCACTTTCCTGAGGTCCGAGTGGATGTTACCAAGATAAAAACGTCTGGGGATGTAAAGGTTGACAGGCCACTGT
GTGACATTGGCGGCAAGGGCCTGTTCATCAAAGAGATAGAAGAGGCCCTGTTGGCCAATAAGATAGACATTGCCGTACAC
TCGGCCAAGGATGTTCCGGGCTTTTATTCCGAAAACTTAGACATGCCGTGCGTACTCAAAAGAAGATCTCCCATGGACGT
TTTTATATCTGTAAAGTACAAAAGCCTAAACTCCTTACCCGCCGGAGCAAAAATCGGCACCTCATCGATCAGAAGAAAGG
TGCAGCTTCTCGCTTTCAGACCAGACCTGGAAATAACCCCCATGCGGGGCAATGTTGACACCAGAATCGCTAAGGTACAA
TCTGGCGAGTGCGACGGTATAGTGCTGGCTGAGGCTGGGGTGGACAGGATATCTGCACGTGCTAAGATCACCGAGGTATT
ACATCCAGACGTGATGTTGGGGGCCGTAGGCCAGGGGGCAATATGCGTTCAGTGTAGAAAAAGCGACGAAGGAATAGTGC
GTATGCTCGCAAAGTTGAACGACCATGAGTCATTCACGGCCGTGCTGGCTGAGCGAAGCTTCATGAAGGCTGTGAACGGC
TCCTGCCACACACCTTTAGCTGCAATGGCTAGGTATGTGGACAGTGGCCTGATGTCGATGAAGTGCATGCTAGCGCATGA
CTCTCGTACCATGGTATCCGCAGAACGCACTTTTCCTGAACGTGATGCAGAAAGTGTGGGCTTTGAAATGGGGGTGATGC
TCAAAGATGAGTTACGGCTTCGTGGCGTATAA

Protein sequence : 
MYAPVVRLGTRGSTLALIQAEEVKAAIAAHFPEVRVDVTKIKTSGDVKVDRPLCDIGGKGLFIKEIEEALLANKIDIAVH
SAKDVPGFYSENLDMPCVLKRRSPMDVFISVKYKSLNSLPAGAKIGTSSIRRKVQLLAFRPDLEITPMRGNVDTRIAKVQ
SGECDGIVLAEAGVDRISARAKITEVLHPDVMLGAVGQGAICVQCRKSDEGIVRMLAKLNDHESFTAVLAERSFMKAVNG
SCHTPLAAMARYVDSGLMSMKCMLAHDSRTMVSAERTFPERDAESVGFEMGVMLKDELRLRGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-47 44
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-47 44