Gene Information

Name : thiC (AMF_322)
Accession : YP_002563449.1
Strain : Anaplasma marginale Florida
Genome accession: NC_012026
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 396112 - 397914 bp
Length : 1803 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGCACCCCTGCAATATACACCATACCCACTTGTGTGATACTCATCGCTGTTCACAACCTAAAAAAGATGGGCACCCTGC
CATAGGGGTGTTGTGCCTCGATGCAAAAGGGTATATACTCCGCCCGAGTTCTAGGTTTTTTATGGATTATTCCGGAGTAT
ATCCGTCATCCTCTAAAGTGTACGTGCGTGGGAATTTGTATTCTGACGTTAATGTTGGAATGCGTAAGGTTGCCATAAAA
AACGGAACGTCTGAGTTTCTTGTATACGATACAGGCGGGCCCTACACTGACCGCGAGGCCAAGCTGGATATCAAATCTGG
CATACGAAAGTTAAGAAGCACTTGGATCGAAAACAGGCGTGATACTTCCCCCGTGCAAAGAAGTTTTGTTCCCAGCGGGA
GTTCATGCACTAGGTATCAAAAAGCAGCAGAGAATGTCCTGCGGAAAATTGCCGGAGGTAGCCCGGTCACACAGCTGTTT
TATGCCCAAAATGGCATTATAACACCAGAAATGGAATACGTAGCTATTCGCGAAAATGCGCTTCGCATGCAGGTAGGTTC
TTCGGAAACTGGGGCTGCTGCGCACCAGGAGATCACTCCGGAGTTTGTGAGGCAGGAGATAGCAGCAGGAAGGGCAATAA
TCCCGGCAAACATTAATCACCCAGAATCCGAACCAATGGTAATTGGAAGGAATTTTCTGGTCAAAATAAACGCCAACATC
GGGAACTCAGCTGTGCTTTCCGGCATTGAAGAAGAAGTGAAAAAGATGGCGCTCGCCGTCGCGTACGGAGCGGACACAGT
TATGGATTTGTCCACAGGGAGTGACATACACAACATCAGAGAATGGATAATAAGAAACAGCCCAGTGCCCATAGGGACGG
TGCCTATATATCAAGCACTCAACAAGGTAAAAGGGGTTGTTGAGAATCTGAGTTTCGAGGTTTTCAAAGAGACGATAATA
GAACAGGCGGAGCAAGGCGTGGATTATTTTACCATCCATGCCGGCGTGCTGAAAGACTACATCAAGCATGCTCGCGGTCG
GGTTACAGGAATAGTCTCCCGAGGCGGCGCTATTATGGCCCAGTGGTGCTTAGCGCACAACAAGGAGAATTTTTTGTACA
CACATTTTGATGAGATCTGCGAAATCATGGGCAGTTACGATGTTGCCTTTTCCTTGGGAGATGGGCTGAGGCCCGGCTCC
ATAGACGATGCAAACGATGAAGCACAGTTTCTGGAACTGAAAACCCTCGGGGAGCTGGTCAAGGTGGCTTGGCACCATGG
TTGCCAGGTAATGGTTGAAGGCCCCGGACATGTGCCCATGCATCTCATAAAAGAGAACATGGAAAAACAACTGCACCTCT
GTAGTGAGGCACCATTTTACACCCTCGGCCCGCTCACGACTGACATAGCACCGGGTTATGACCATATCACTAGTGCTATA
GGCGCAGCGATGATCGGGTGGTACGGCACTGCGATGCTGTGTTACGTAACTCCAAAAGAGCACTTAGGGCTGCCGAATAT
TGATGACGTAAAAGCGGGGGTGATATCCTATAAAATTGCGGCACACGCCGCTGATCTGGCAAAAGGAAATCCATCCGCCT
ATGCTAGAGATTACGCGCTGAGCCAGGCAAGGTTTGATTTCCGATGGTACGATCAGTTCAATCTCTCGCTAGACCCGCTA
ACTGCAAAGTCGCTACACGATGAATCTCTGCCCGGCAAGGGAGGCAAAACTGCAAATTTCTGTTCCATGTGTGGGCCGAA
ATTTTGCTCAATGAAACTGAGCAAAGAGTTGGTAGACCAATAG

Protein sequence :
MHPCNIHHTHLCDTHRCSQPKKDGHPAIGVLCLDAKGYILRPSSRFFMDYSGVYPSSSKVYVRGNLYSDVNVGMRKVAIK
NGTSEFLVYDTGGPYTDREAKLDIKSGIRKLRSTWIENRRDTSPVQRSFVPSGSSCTRYQKAAENVLRKIAGGSPVTQLF
YAQNGIITPEMEYVAIRENALRMQVGSSETGAAAHQEITPEFVRQEIAAGRAIIPANINHPESEPMVIGRNFLVKINANI
GNSAVLSGIEEEVKKMALAVAYGADTVMDLSTGSDIHNIREWIIRNSPVPIGTVPIYQALNKVKGVVENLSFEVFKETII
EQAEQGVDYFTIHAGVLKDYIKHARGRVTGIVSRGGAIMAQWCLAHNKENFLYTHFDEICEIMGSYDVAFSLGDGLRPGS
IDDANDEAQFLELKTLGELVKVAWHHGCQVMVEGPGHVPMHLIKENMEKQLHLCSEAPFYTLGPLTTDIAPGYDHITSAI
GAAMIGWYGTAMLCYVTPKEHLGLPNIDDVKAGVISYKIAAHAADLAKGNPSAYARDYALSQARFDFRWYDQFNLSLDPL
TAKSLHDESLPGKGGKTANFCSMCGPKFCSMKLSKELVDQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-178 65
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-178 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-166 60