Gene Information

Name : phoP (SUB0567)
Accession : YP_002561912.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Virulence
Product : alkaline phosphatase synthesis transcriptional regulatory protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 536795 - 537517 bp
Length : 723 bp
Strand : +
Note : Similar to SUB0552, 50.847% identity (52.402% ungapped) in 236 aa overlap (1-232:1-233)

DNA sequence :
ATGAAAAAACATATTTTATTAGTCGATGATGAAGAACATATCTTACGTCTATTAGATTATCATTTGAAAAAAGAAGGTTA
TGAGACAGATCTTGCTGAGGATGGTAGGACAGCGCTAAAACTAGCAGAATCTGAACATTATGATTTTATTTTATTAGACA
TTATGTTGCCACAATTAGATGGTATTGAAGTCTGTAAAAGAATCCGTTCCAAGGGAAACAAGACTCCAATTATGATGGTA
TCTGCTAAAGGGGAGGAGTTTGATAAAGTACTAGCACTTGAACTTGGTGCTGATGATTATATGACAAAACCTTTTAGTCC
TAGAGAGTTAATTGCCAGATTAAAGGCTATTTTAAGACGAACTGAAAAAACTGAAGAAGAGGATACTACAGGTTTACCAG
AAGAATATTGGACTATTAATCACTTGGTTATTTATCCTGAAAGGCATGAAGTTTATAAAAATCAAAAGTTACTAAATCTA
ACACCGAAAGAATTTGAACTCTTACTTTATCTAGTCAAACATCCTAATATGACTCTAACAAGAGAACGACTCTTAGAACG
GATATGGGGTTATGATTTTGGACAAGAAACCCGTTTGGTAGATGTCCATATTGGTAAGTTGAGAGAAAAAATTGAGGATG
ATCCTAAAAAACCAGTGTTTATCAAAACGATTCGTGGATATGGTTATAAATTTAAGGAGCTAAAGGATGAAACAAAATCT
TAG

Protein sequence :
MKKHILLVDDEEHILRLLDYHLKKEGYETDLAEDGRTALKLAESEHYDFILLDIMLPQLDGIEVCKRIRSKGNKTPIMMV
SAKGEEFDKVLALELGADDYMTKPFSPRELIARLKAILRRTEKTEEEDTTGLPEEYWTINHLVIYPERHEVYKNQKLLNL
TPKEFELLLYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDDPKKPVFIKTIRGYGYKFKELKDETKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-38 41
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 3e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_012469.1.7686381. Protein 4e-88 78
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_003923.1003749.p0 Protein 1e-58 54
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein HE999704.1.gene2815. Protein 2e-57 54
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_002952.2859905.p0 Protein 3e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_007793.3914279.p0 Protein 1e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_002745.1124361.p0 Protein 1e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_009782.5559369.p0 Protein 1e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_002951.3237708.p0 Protein 1e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_007622.3794472.p0 Protein 2e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_002758.1121668.p0 Protein 1e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_009641.5332272.p0 Protein 1e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_013450.8614421.p0 Protein 1e-58 53
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein AE016830.1.gene1681. Protein 4e-57 50
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_012469.1.7685629. Protein 5e-44 50
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein CP001485.1.gene721.p Protein 5e-38 45
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein HE999704.1.gene1528. Protein 3e-37 44
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein AF155139.2.orf0.gene Protein 7e-37 43
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein AM180355.1.gene1830. Protein 3e-36 43
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein AE000516.2.gene3505. Protein 1e-39 43
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein DQ212986.1.gene4.p01 Protein 3e-36 42
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein CP004022.1.gene3215. Protein 5e-33 42
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_014475.1.orf0.gen Protein 5e-33 41
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein NC_005054.2598277.p0 Protein 5e-33 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein VFG1563 Protein 1e-38 41
phoP YP_002561912.1 alkaline phosphatase synthesis transcriptional regulatory protein VFG1702 Protein 1e-38 41