Gene Information

Name : smpB (SUB0524)
Accession : YP_002561869.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 495088 - 495555 bp
Length : 468 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAAAGGCGAAGGTAATTTACTCGCACAAAATAAGAAGGCTAGCCATGACTATCATATCGTTGAGACTATTGAAGC
GGGGATTGTGTTAACAGGGACTGAAATTAAAAGTGTCCGAGCTGCCCGCATTCAACTAAAGGATGGCTTTGCACAGATTA
AAAATGGTGAAGCTTGGTTAATGAATGTTCACATTGCCCCATTTGAGCAAGGGAATATCTGGAATGCAGATCCTGAGAGA
ACACGGAAACTATTGCTCAAAAAACGTGAAATTAACCATCTTGCAAATGAATTGAAAGGGACAGGGATGACCCTGATTCC
CTTAAAAGTTTACCTAAAAGATGGTTTTGCCAAAATCTTACTAGGTTTAGCGAAAGGTAAACATGATTATGATAAACGTG
AGTCAATAAAACGACGCGAACAAGACCGTGACATTAAACGAGTGATGAAAAGCATTAATGCACGCTAA

Protein sequence :
MAKGEGNLLAQNKKASHDYHIVETIEAGIVLTGTEIKSVRAARIQLKDGFAQIKNGEAWLMNVHIAPFEQGNIWNADPER
TRKLLLKKREINHLANELKGTGMTLIPLKVYLKDGFAKILLGLAKGKHDYDKRESIKRREQDRDIKRVMKSINAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 9e-38 57
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-35 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-21 42