Gene Information

Name : leuS (SUB1729)
Accession : YP_002563002.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1709081 - 1711582 bp
Length : 2502 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACATTTTATAATCACAAAGAAATAGAACCCAAATGGCAAGACTTTTGGGCAAAAAACCACACCTTTAAAACAGGAAC
TGATAGCTCTAAACCAAAATTTTATGCTTTAGACATGTTCCCTTATCCCTCTGGAGCAGGCTTACACGTTGGTCACCCAG
AAGGCTACACAGCAACTGATATCTTAAGCCGTTTTAAACGCGCACAAGGTTATAATGTCCTTCACCCAATGGGTTGGGAT
GCCTTTGGTTTACCTGCAGAACAATATGCTATGGATACCGGTAATGACCCAGCAGATTTTACAGCTGAAAACATTGCCAA
CTTTAAACGCCAAATCAACTCATTAGGTTTCTCCTATGATTGGGACCGAGAAGTGAACACAACGGATCCTAATTATTACA
AATGGACTCAGTGGATTTTTACTAAACTTTATGAAAAAGGCTTAGCCTATGAAGCCGAGGTTCCCGTAAACTGGGTTGAG
GAATTGGGCACAGCTATTGCTAATGAAGAAGTTCTACCTGACGGCACCTCAGAACGTGGTGGTTATCCAGTTGTTCGTAA
GCCAATGCGTCAATGGATGCTAAAAATCACAGCCTATGCAGAACGACTCCTTGAAGATCTCGAAGAAGTTGATTGGCCAG
AGTCGATCAAAGATATGCAACGCAATTGGATTGGTAAATCAGTTGGGGCAAATATTACTTTTAATGTGAAAGATTCTGAG
GAAAGTTTCACGGTCTTCACAACACGACCTGACACCTTGTTTGGGGCAACCTATGCAGTCTTAGCGCCAGAGCATGCGCT
TGTAGATGCCATTACAACAGAAGAACAAGCTGAAGCCATAGCAGAATACAAACGACAAGCTAGCCTAAAATCAGATTTAG
CACGGACAGATCTAGCGAAAGAAAAAACAGGTGTTTGGACAGGAGCCTATGCCATTAACCCTGTCAATGGAAAAGAAATG
CCAATCTGGATTGCCGATTATGTCCTATCAAGCTATGGAACAGGTGCCATCATGGCAGTACCAGCCCACGATGAACGCGA
CTGGGAGTTTGCTAAACAATTTCATTTGGATATTATTCCAGTTTTAGAAGGTGGTAATGTTCAAGAAGCAGCCTATACAG
AAGATGGACTTCATATCAATTCAGACTTTTTAGATGGCTTAAACAAAGAAGAAGCCATTGCTAAAACGGTTGCTTGGTTG
GAAGAAAAAGAAGTTGGAAATGAAAAAGTTAGCTACCGTCTCCGTGATTGGCTCTTTTCTCGCCAACGTTATTGGGGGGA
ACCAATTCCAATCATTCATTGGGAAGATGGGACGTCAACAGCAGTTCCAGAAGATCAGCTACCACTGATTCTACCTGTAA
CAAAAGATATTCATCCTTCAGGGACTGGTGAGTCGCCATTGGCTAATATCACTGATTGGTTAGAAGTGACGCGCGAAGAC
GGTGTTAAAGGTCGTCGCGAGACCAATACAATGCCACAATGGGCTGGCTCTAGCTGGTACTACCTTCGCTACATTGATCC
TAAAAATGACAAAGCGATTGCTGATCCAGACTTACTAAAACAATGGCTACCGGTCGATATTTATGTGGGGGGTGCTGAAC
ATGCGGTTCTTCACTTGCTATATGCGCGTTTCTGGCATAAAGTACTTTATGATTTGGGTGTTGTACCAACCAAAGAACCT
TTCCAAAAACTCTTTAATCAAGGGATGATTTTGGGAACAAGTTACCGTGATCATCGTGGGGCATTGGTTGCAACTGATAA
AGTGGAAAAACGCGAGGGTTCTTATTTCCATATCGAAACCGGGGAAGAACTTGAACAAGCACCTGCTAAGATGTCTAAAT
CCCTAAAAAATGTGGTCAATCCGGATGATGTCGTTGAGCAATATGGTGCCGATACGCTTCGTGTTTATGAAATGTTCATG
GGACCATTAGATGCTTCAATTGCTTGGTCTGAAGAAGGTCTTGAAGGTAGCCGTAAGTTCTTGGACCGTGTCTATCGTTT
GATCACGACTAAGGAGATGACTGGCGACAATAGCGGTGCTTTGGATAAAGTTTATCATGAGACTGTAAAAGCAGTGACTG
AACAAATTGAAAGCATGAAATTCAATACCGCCATTGCCCAATTGATGATTTTTGTAAATGCTGCTAATAAAGAGGATAAA
CTTTATAAAGAGCAAGCCAAAGGCTTTGTTCAATTAATCGCTCCTTTTGCACCACACTTAGGAGAAGAATTATGGCAAGT
ATTAACAGACTCAAATCAATCAATTTCTCATGTTGCTTGGCCAACTTGGGATGAAAACAAACTTGTTGAAAATGATGTTG
AAATTGTTGTTCAAATTAAAGGGAAAGTTAAAGCAAAACTTGTTCTTGCCAAAGATTTAAGCAAAGAAGAATTAGAAGCT
GCAGCCCTTTCTCATGAAAAAATACAAGCAGAAATTGCAGGCAAAGAAATCGTAAAAGTCATCGCAGTTCCTAACAAGTT
GGTTAATATTGTGGTGAAATAA

Protein sequence :
MTFYNHKEIEPKWQDFWAKNHTFKTGTDSSKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWD
AFGLPAEQYAMDTGNDPADFTAENIANFKRQINSLGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSVGANITFNVKDSE
ESFTVFTTRPDTLFGATYAVLAPEHALVDAITTEEQAEAIAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEM
PIWIADYVLSSYGTGAIMAVPAHDERDWEFAKQFHLDIIPVLEGGNVQEAAYTEDGLHINSDFLDGLNKEEAIAKTVAWL
EEKEVGNEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEDQLPLILPVTKDIHPSGTGESPLANITDWLEVTRED
GVKGRRETNTMPQWAGSSWYYLRYIDPKNDKAIADPDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP
FQKLFNQGMILGTSYRDHRGALVATDKVEKREGSYFHIETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM
GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEMTGDNSGALDKVYHETVKAVTEQIESMKFNTAIAQLMIFVNAANKEDK
LYKEQAKGFVQLIAPFAPHLGEELWQVLTDSNQSISHVAWPTWDENKLVENDVEIVVQIKGKVKAKLVLAKDLSKEELEA
AALSHEKIQAEIAGKEIVKVIAVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 90