Gene Information

Name : polA (SUB1716)
Accession : YP_002562989.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1692950 - 1695595 bp
Length : 2646 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAAACAAGAATAGATTATTATTAATTGATGGCTCATCTGTAGCCTTTCGTGCCTTTTTTGCTTTATACCAACAGAT
TGATCGTTTTAGAAACCAAGCTGGCTTACATACCAATGCTATTTATGGTTTCCATTTAATGCTCGATCATATGATGAAGC
GCGTGCAGCCAACACATATCCTGGTGGCTTTTGATGCGGGAAAAACAACCTTCCGTACAGAAATGTACGCGGATTATAAA
GGGGGACGTGCCAAAACTCCTGATGAATTCCGTGAACAGTTTCCATACATCAGAGAAATGCTAAAAGCTCTAGGTGTGCC
ATATTACGATTTGGTGAACTACGAAGCCGACGATATTATTGGTACTTTGGATAAAATAGCAGAGCGGACAGAAGTGCCAT
TTGATGTGACAATAGTCAGTGGTGATAAGGATTTAATTCAATTAACTGACGCTAACACAGTTGTTGAAATCTCCAAAAAA
GGAGTTGCCGAATTTGAAGAATTCACTCCGGACTATCTGATGGAAAAGATGGGCATTACCCCAGAACAATTCATTGATTT
GAAAGCCCTAATGGGTGACAAATCAGATAATATTCCAGGTGTTACTAAAATTGGTGAGAAGACTGGCTTAAAACTCTTAC
AGGAATATGGCAGTTTAGAAGGCATTTATGCAAACGTTGATTCTTTCAAGCCTTCTAAGATGAAAGAGAATTTAATCAAT
GATAAAGCGCAAGCCTTTTTATCAAAAACCTTGGCAACTATTGATACCAATGCTCCTATCACAATTGGTTTAGAAGACTT
GGTCTATCACGGTCCAAATCATGAGGCACTTGCCTCCTTTTATGATGAGATGGGCTTTGTGCAATTGCGTGCAGCTTTAT
CGAATCAATTGCCGAAAGAGCCAGAAGAAGAGATTGTCTACCATGAAGTGGTCGATGACATCAGTCCAGACATGTTCACC
GATGATACTTTCATTTATTTTGAACTCTTAAATGACAATTACCACCGTGAAGACATTACAACTTTTGCTTGGGGAAATAC
TGAAAACATTTATGTCTCTCAAAATCCTGAAGTCTTGAAAACAGATGTCTTTCAGGCCTTTTTGAGAAAGCCGATGGCAA
CCTATGATTTTAAAAGAGCTAAGATCTTATTGAGTCATTTAAACATTGATGTGCCAAGAGGAGCTTTCGATGCCCGTTTG
GCCAATTACCTTTTGTCAAATGTTGATGATAATCAGTTGTCAACCATAGCAAGGGTGCATACCAATATCCATTTGGAATC
AGATGATGTGGTATACGGAAAAGGGGTGAAACGTGCTTTTCCAGACAAAGGCCTCCTTTTTGCTCATTTAGCCAAAAAAA
TCAAAGTTTTGGTTGAAAGCAAAGCGACTATGCTAGACAAGTTGTCTGACCATGATCAACTGGCACTTTTTGAAGACATT
GAGATGCCCTTAGCAAATGTTCTCGCAAAGATGGAGATCACTGGTATTAAGGTCAATAAAGAAACCTTAGTTGAAATGGC
TGAGCAAAATAAGGTGATTATTGATAGGCTGACGCAAGAAATTTATGACTTGGCTGGTGAAGAATTCAACATTAATTCTC
CAAAGCAATTAGGATCGATTTTATTTGAAAAGATGCAATTGCCTATAGAAATGACAAAGAAAACTAAGACAGGTTATTCC
ACTGCTGTTGATGTCTTAGAACGTCTAGCCCCAATTGCACCAGTCGTTGCCAAAATATTAGACTACCGTCAAATTACAAA
ATTGCAGTCTACCTATTTGATTGGTCTTCAAGATTATATTATGGAAGATGGGAAAATCCATACCAGATATGTTCAGGATT
TAACCCAAACAGGTCGACTCTCAAGTATTGATCCCAACCTTCAAAATATCCCTATCCGAATGGAACAGGGGCGCTTGATC
CGTAAGGCTTTTACGGCATCGTCAGAAGATGCTCTTTTGTTGAGTTCGGATTATTCTCAAATCGAATTACGTGTCTTAGC
TCATATTTCAGGAGATCAACATTTGATTACTGCCTTTAATGAAGATGCGGATATTCACACATCCACAGCTATGCGTGTCT
TTGCTATTGACAAGGAAGAAGATGTGACTGCTAACGACCGTCGTAATGCAAAGGCAGTAAACTTTGGAATTGTCTATGGT
ATTTCTGATTTTGGCTTATCTAACAATTTAGGCATCAGTCGTCAAAAAGCAAAAGAATACATTAATACTTATTTTGACCG
ATATCCAGGAATCAAAGATTATATGGATTCTATTGTTCGGGAAGCTAAAGATAAAGGCTATGTGGAAACACTCTTTAAAC
GTCGTCGTGAACTACCAGATATTAATTCACGCAATTTTAATGTGAGATCTTTTGCAGAACGGACAGCTATTAATTCGCCT
ATTCAGGGTAGTGCTGCCGATATTCTCAAAATTGCCATGATTAATTTAGATAAGGCCTTAGAAGAGGGGCGCTTCAAAAC
AAAAATGCTCTTGCAGGTACATGATGAAATTGTTTTAGAAGTGCCAAAAGATGAACTCGAGAAGGTCAAACAACTGGTCA
AAGAAACTATGGAGCATGCTGTTGATTTATCAGTTCCTTTAAGGGCAGATGAAAATTCAGGTAAGAGTTGGTACGAGGCT
AAGTAG

Protein sequence :
MENKNRLLLIDGSSVAFRAFFALYQQIDRFRNQAGLHTNAIYGFHLMLDHMMKRVQPTHILVAFDAGKTTFRTEMYADYK
GGRAKTPDEFREQFPYIREMLKALGVPYYDLVNYEADDIIGTLDKIAERTEVPFDVTIVSGDKDLIQLTDANTVVEISKK
GVAEFEEFTPDYLMEKMGITPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLQEYGSLEGIYANVDSFKPSKMKENLIN
DKAQAFLSKTLATIDTNAPITIGLEDLVYHGPNHEALASFYDEMGFVQLRAALSNQLPKEPEEEIVYHEVVDDISPDMFT
DDTFIYFELLNDNYHREDITTFAWGNTENIYVSQNPEVLKTDVFQAFLRKPMATYDFKRAKILLSHLNIDVPRGAFDARL
ANYLLSNVDDNQLSTIARVHTNIHLESDDVVYGKGVKRAFPDKGLLFAHLAKKIKVLVESKATMLDKLSDHDQLALFEDI
EMPLANVLAKMEITGIKVNKETLVEMAEQNKVIIDRLTQEIYDLAGEEFNINSPKQLGSILFEKMQLPIEMTKKTKTGYS
TAVDVLERLAPIAPVVAKILDYRQITKLQSTYLIGLQDYIMEDGKIHTRYVQDLTQTGRLSSIDPNLQNIPIRMEQGRLI
RKAFTASSEDALLLSSDYSQIELRVLAHISGDQHLITAFNEDADIHTSTAMRVFAIDKEEDVTANDRRNAKAVNFGIVYG
ISDFGLSNNLGISRQKAKEYINTYFDRYPGIKDYMDSIVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSP
IQGSAADILKIAMINLDKALEEGRFKTKMLLQVHDEIVLEVPKDELEKVKQLVKETMEHAVDLSVPLRADENSGKSWYEA
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 80