Gene Information

Name : hasB1 (SUB1696)
Accession : YP_002562970.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase 1
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 1675606 - 1676811 bp
Length : 1206 bp
Strand : -
Note : Similar to SUB1027, 58.293% identity (59.900% ungapped) in 410 aa overlap (2-401:3-411)

DNA sequence :
GTGAAAATTGCAGTTGCAGGTTCTGGCTATGTTGGCCTATCATTAAGTGTATTATTAGCACAGAAAAATCCTGTTACAGT
TGTAGATATTATTGAGAAGAAAGTAAATCTCATAAATCAAAAACAATCACCAATCCAGGATGTTGATATTGAAAACTATT
TAAAAGAAAAAAAGTTACAATTAAGAGCTACTCTAGACGCCGATCAAGCATTTAGGGATGCAGATATACTAATTATTGCT
ACACCAACCAATTATGATGTGGAGAAGAATTTTTTTGATACTAGTCATGTTGAGACTGTAATTGAGAAAGCTTTAGCTTT
AAATAGTCAGGCTTTGTTAGTTATTAAATCAACGATACCACTTGGTTTTATTAAAAAGATGCGTCAAAAATATCAGACAG
ACCGTATTATTTTTAGTCCCGAATTTCTTAGAGAGTCTAAAGCTTTAAAAGATAATCTTTATCCTAGTCGAATAATTGTT
TCCTTTGAAGATGATGATTCTATGGAAGTAATAGAAGCAGCAAAGACTTTTGCTCAATTGTTAAAAGATGGTTCTTTGGA
TAAAGATGTTCCTGTACTTTTTATGGGTTCAGCAGAGGCTGAAGCAGTAAAATTATTTGCCAATACCTATTTAGCTATGC
GTGTCTCCTATTTTAATGAGTTAGATACATATGCTGAAAAGAATGGTTTACGTGTGGATAATATTATTGAGGGCGTTTGC
CATGATCGACGCATAGGAATTCATTATAATAACCCTTCTTTTGGCTATGGAGGATACTGCTTACCTAAAGATACCAAACA
GTTGCTAGCAAGCTATGATGGTATTCCTCAATCGCTTATAAAAGCAATTGTTGATTCTAATAAAATTCGTAAAGAGTATA
TCGCATCACAAATTTTACAACAATTGAGTGATATTAATGTAGATCCTAAAGATGCAACGATTGGTATTTACCGCCTTATC
ATGAAAAGTAACTCTGATAATTTCAGAGAGAGTGCAATAAAAGATATTATTGATCATATTAAGAGCTATCAAATTAATAT
AGTCTTGTATGAGCCAATGATGAATGAAGATTTTGATTTACCAATCATTGATGATTTATCTGACTTCAAAGCCATGTCAC
ATATTATCGTTTCAAATAGATATGATTTAGCCTTAGAAGATGTTAAAGAAAAAGTTTACACCAGAGATATTTACGGTGTG
GATTAA

Protein sequence :
MKIAVAGSGYVGLSLSVLLAQKNPVTVVDIIEKKVNLINQKQSPIQDVDIENYLKEKKLQLRATLDADQAFRDADILIIA
TPTNYDVEKNFFDTSHVETVIEKALALNSQALLVIKSTIPLGFIKKMRQKYQTDRIIFSPEFLRESKALKDNLYPSRIIV
SFEDDDSMEVIEAAKTFAQLLKDGSLDKDVPVLFMGSAEAEAVKLFANTYLAMRVSYFNELDTYAEKNGLRVDNIIEGVC
HDRRIGIHYNNPSFGYGGYCLPKDTKQLLASYDGIPQSLIKAIVDSNKIRKEYIASQILQQLSDINVDPKDATIGIYRLI
MKSNSDNFRESAIKDIIDHIKSYQINIVLYEPMMNEDFDLPIIDDLSDFKAMSHIIVSNRYDLALEDVKEKVYTRDIYGV
D

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 2e-77 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasB1 YP_002562970.1 UDP-glucose 6-dehydrogenase 1 VFG0963 Protein 7e-111 63