Gene Information

Name : secA (SUB1537)
Accession : YP_002562824.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1525815 - 1528343 bp
Length : 2529 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCAAATATTCTACGCAAAGTCATTGAAAATGACAAAGGCGAAATTAGAAAACTCGAAAAAATTGCAAAAAAAGTTGA
AGCTTACGCTGATGAGATGGAAGCTTTGACAGACCAAGAGTTACAAGCAAAGACACCTGAATTTAAAAAACGTTATCAAG
CAGGAGAAACATTAGAAGACTTGCTACCAGAAGCATTTGCGGTAGTACGTGAGGCTTCTAGACGTGTTTTGGGGTTATAC
CCTTATCGTGTCCAAATCATGGGGGGAGTTGTTCTTCATAACGGAGACGTTCCTGAAATGCGTACAGGTGAAGGAAAGAC
TCTAACAGCTACAATGCCAGTTTACCTTAATGCCTTAGCGGGCGAAGGGGTTCACGTTATCACAGTTAACGAATATTTAT
CAACACGTGATGCCACCGAAATGGGTGAAGTCTATAGTTGGTTAGGACTTTCTGTTGGTATTAACTTAGCTGCCAAATCC
CCTGCTGAAAAGCGTGAGGCTTATTTATGTGATATCACTTATTCAACTAACTCAGAGGTAGGATTTGACTACTTACGTGA
TAACATGGTTGTTCGCCAAGAAGATATGGTTCAAAGACCACTTAACTTCGCATTGGTCGATGAGGTTGATTCGGTATTGA
TCGATGAGGCTCGTACGCCATTGATTGTTTCTGGGGCAGTAAGTTCTGAAACGAACCAACTGTATGTCAGAGCTGATATG
TTTGTTAAAACTTTGAAGGAAGATGACTATATCATTGATGTTCCAACAAAGACAATTGGTTTGAGCGATTTAGGAATTGA
CAAAGCTGAAAGCTATTTTAACCTTAATAACCTTTATGATATTGATAATGTTGCCTTAACACACTTCATTGATAATGCTT
TAAGAGCTAACTACATCATGCTCTTAGACATTGATTATGTTGTCAGTGAAGATGGTGAAATTTTGATTGTCGACCAATTT
ACAGGTCGTACCATGGAAGGACGCCGCTTCTCCGATGGTTTACACCAAGCCATTGAAGCCAAAGAAGGCGTACGCATTCA
GGAAGAATCCAAAACAAGCGCATCTATTACTTATCAAAATATGTTCCGCATGTACAAAAAACTAGCAGGAATGACTGGTA
CTGCAAAAACAGAGGAAGAAGAATTCCGCGAAGTTTACAACATGCGAATCATTCCAATCCCTACCAACAAACCTGTAGCT
CGTTTGGATCACACGGATTTACTTTACCCAACACTTGCTTCTAAATTTAGAGCTGTTATTGCGGATGTCAAAGCTCGTCA
TGAGAAAGGGCAACCCGTCTTAGTTGGTACAGTAGCTGTTGAAACCAGTGATTACATTTCAAAACAACTTGTGGCAGCTG
GCGTTCCTCATGAAGTACTGAATGCTAAAAACCACTTTAAAGAGGCACAAATTATTATGAATGCTGGACAACGCGGAGCT
GTCACCATTGCAACCAACATGGCTGGTCGTGGTACCGACATCAAATTGGGTGAAGGTGTTCGTGAACTTGGAGGTTTGTG
TGTTATTGGTACGGAACGTCATGAAAGTCGTCGTATTGATAATCAGTTGCGTGGACGTGCCGGGCGTCAAGGGGATCCAG
GTGAATCACAATTTTACCTTTCATTAGAAGACGATCTCATGAGACGTTTTGGTTCAGACAGAATCAAGGCCTTTCTAGAT
AGAATGCGTCTTGAGGAAGAAGATGCTGTAATTAAGTCAGGTATGCTTGCGCGCCAAGTTGAGTCAGCTCAAAAACGGGT
TGAAGGAAACAACTATGATACCCGTAAGCAAGTCTTGCAATACGATGATGTTATGCGTGAGCAAAGGGAAATCATTTATG
CTAACCGTCGTGATGTCATTACAGCCAATCGTGATTTAGGCCCTGAAATCAAAGCCATGATTAAAAGGACTATTAAACGA
ACAGTTGATGCTCATGCACGTAGCAATCGTAATGACGCCATTGATGCGATTGTAGCATTTGCTAGAACCAATATTGTTCC
GGAAGAATCTATCTCAGCTAAGGACTTACGTTCCCTAAAAGATGATCAAATCAAAGAAGAGCTCTATAAACGTGCATTGG
CAATTTACGAAAGTCAGATTTCTAAATTGCATGATCAAGAAGCTGTTTTAGAATTCCAAAAAGTGCTTATTCTTATGATT
GTAGACAATAAATGGACGGAACATATTGATGCCTTGGATCAATTGCGTAACTCTGTTGGCCTTCGTGGCTATGCTCAGAA
CAATCCGGTGGTTGAATACCAATCAGAAGGGTTTAAAATGTTCCAAGACATGATAGGAGCTATTGAGTTTGATGTCACAC
GGACAATGATGAAGGCACAAATTCATGAACAAGAACGTGAACGTGTTTCTCCGAATGCTAGAACCACAGCTGCACAAAAT
ATTGCTGCCCAATCTAACCAATCTAGCGAAAGCTCAACTCAAGATTACTCACATGTCAAACGTAATGACCTGTGTCCATG
TGGTTCAGGTAAGAAGTTTAAAAATTGTCATGGACGAAAAGCGTTTTAA

Protein sequence :
MANILRKVIENDKGEIRKLEKIAKKVEAYADEMEALTDQELQAKTPEFKKRYQAGETLEDLLPEAFAVVREASRRVLGLY
PYRVQIMGGVVLHNGDVPEMRTGEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYVRADM
FVKTLKEDDYIIDVPTKTIGLSDLGIDKAESYFNLNNLYDIDNVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQF
TGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNKPVA
RLDHTDLLYPTLASKFRAVIADVKARHEKGQPVLVGTVAVETSDYISKQLVAAGVPHEVLNAKNHFKEAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRAGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLD
RMRLEEEDAVIKSGMLARQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIKR
TVDAHARSNRNDAIDAIVAFARTNIVPEESISAKDLRSLKDDQIKEELYKRALAIYESQISKLHDQEAVLEFQKVLILMI
VDNKWTEHIDALDQLRNSVGLRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERVSPNARTTAAQN
IAAQSNQSSESSTQDYSHVKRNDLCPCGSGKKFKNCHGRKAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 8e-143 42