Gene Information

Name : serS (SUB1489)
Accession : YP_002562777.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1480748 - 1482025 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAACGTATTCGTACAGATTTTGAAACCGTTGCCCAAAAATTAGCCACTCGTGGCGTTTCAGAAGACAG
TCTTAATCATTTGAAAGAGTTAGATGAAAAACGTCGCCAACTCTTAGTTAGTTCAGAAGAATTAAAAGCTGAGCGCAATC
TATCTTCTGCTGCTATTGCACAAGCTAAACGCAATAAAGAAGATGCTAGTCAACAAATTGCAGAAATGCAAAAAATGTCT
GCTGATATCAAAGCAATTGATGCCGAATTAGCAGAAATTGATGAAAAAGTAACCGAAATCATCACAGTCTTACCAAATAC
ACCTCACGATTCCGTACCAGTGGGTGCCGATGAAGATGACAATGTCGAAATCCGCCGTTGGGGAACACCACGAGAATTTG
ATTTCGAAATCAAAGCGCACTGGGATTTAGGGGAAGATTTAGATATCCTTGACTGGGAACGTGGTGCTAAAGTTACCGGC
GCTCGCTTCCTCTTTTATAAAAATTTAGGTGCCCGACTAGAACGTGCTTTGTACAATTTCATGCTAGACGAACATGCTAA
AGAAGGCTACCAAGAAATCATCACTCCATACATGGTTAATCACGACTCTATGTTTGGTACAGGACAATATCCAAAGTTTA
AAGAAGACACTTTTGAACTCAAAGATTCTAACTTTGTTTTGATTCCAACAGCCGAAGTTCCTTTAACCAACTACTACCGT
GGTGAGATTTTGGATGGAAAAGACCTACCCATTAATTTCACAGCAATGAGTCCATCTTTCCGCTCCGAAGCAGGTTCTGC
CGGTCGCGATACGCGTGGATTAATTCGTTTGCATCAGTTCCACAAAGTTGAAATGGTAAAATTTGCTAAACCAGAGGAAT
CTTATGAAGAATTGGAAAAAATGACAGCCAATGCTGAGAACATCTTACAGAAATTAAACCTTCCTTATCGTGTTCTAGCC
CTCTGTACTGGGGATATGGGCTTCTCAGCAGCCAAAACTTACGATTTAGAAGTTTGGATTCCTGCCCAAAATACTTACCG
CGAAATATCATCATGTTCAAATACTGAGGATTTCCAAGCAAGACGTGCTCAAATTCGTTACCGTGATGAAGCTGATGGTA
AAGTAAAATTATTACATACCTTAAATGGTTCTGGATTAGCTGTCGGTCGTACCGTAGCTGCTATTTTAGAAAATTATCAG
AACGAGGATGGTTCAGTAACTATACCAGAAGTTTTACGTCCGTATATGGGCGGAGCAGAAATGATTTCTCCAAAGTAA

Protein sequence :
MLDLKRIRTDFETVAQKLATRGVSEDSLNHLKELDEKRRQLLVSSEELKAERNLSSAAIAQAKRNKEDASQQIAEMQKMS
ADIKAIDAELAEIDEKVTEIITVLPNTPHDSVPVGADEDDNVEIRRWGTPREFDFEIKAHWDLGEDLDILDWERGAKVTG
ARFLFYKNLGARLERALYNFMLDEHAKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELKDSNFVLIPTAEVPLTNYYR
GEILDGKDLPINFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVLA
LCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQ
NEDGSVTIPEVLRPYMGGAEMISPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-179 87