Gene Information

Name : tkt1 (SUB1427)
Accession : YP_002562725.1
Strain : Streptococcus uberis 0140J
Genome accession: NC_012004
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1425203 - 1427188 bp
Length : 1986 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGACATTTGATGCAGTTGATCAGTTGGCAGTGAATACTGTCCGTACACTTTCTATGGATGCTATTCAAAAGGCAAATTC
AGGTCACCCTGGCTTACCAATGGGTGCAGCCCCAATGGCATATGTGTTGTGGAATCGTTTCATGACCGTTAACCCCAAAA
CAAGCCGCAATTGGACAAACCGTGACCGCTTTGTTTTATCAGCAGGACATGGAAGTGCCATGTTATATAGTCTCTTACAC
CTAGCAGGCTATAATCTTTCTATTGAGGATATTAAGAATTTCCGCCAATGGGGATCTAAAACCCCAGGACATCCTGAAGT
CAATCACACAGATGGCGTTGAAGCAACTACTGGACCACTTGGTCAAGGTATTGCCAACGCAGTCGGTTTAGCCATGGCCG
AAGCTCACCTTGCAGCTAAATACAATAAACCAGGATATAATATTGTAGATCATTACACCTATGCCTTGAATGGTGACGGG
GACTTGATGGAAGGCGTCAGCCAGGAAGCAGCTAGCTTAGCCGGCCACTTAAAACTAGGGAAATTAGTCCTTCTTTATGA
TTCAAATGACATTTCACTTGATGGTCCAACATCAATGGCTTTCACAGAAGATGTTAAAGGTCGTTTTGAAGCCTATGGAT
GGCAACATATCTTAGTTAAAGACGGTAATGATTTAGAAGCAATTGCCAAAGCTCTTGAAGAAGCTAAAGCTGAAACTCAA
AAACCAACCATTATTGAAGTCAAAACTATCATTGGTTACGGTGCTGAAAAACAAGGAACTTCAGCCGTCCATGGCGCTCC
TCTAGGTGCAGAAGGCATTGCATTTGCTAAAAAAGCTTACCAATGGACAGCTGAAGACTTCGAAGTACCAGCAGAAGTTT
CAAAACGTTTCGAAGAAGGAATTCAAACAAAAGGTGCACAAGCAGAAGCAGCTTGGAATGAGCTTTTTGCAGCTTATGAA
AAAGAGTACCCAGAATTAGCAGCTGATTATAAAGCAGCTTTTGCAAACGAGCCAGTGTCAGTTGACTTGGCAGCACATGA
ACTTGGTACATCAAAAGCAAGTCGTGTATCAAGTCAGGAAGCTATTCAACAAATTTCAGAACAAGTGTCATCATTCTGGG
GAGGTTCAGCAGACCTTTCAGCATCTAATAACACAATGGTCAAAGTAGAAAAAGACTTCCAGCCAGGTCAATATGAAGGA
CGTAACATATGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCTATGAATGGTATTGCTCTACATGGTGGAACTCGTGT
CTACGGTGGAACATTCTTCGTCTTCTCAAACTATCTCTTACCAGCTGTACGTATGGCAGCTCTTCAAAACCTACCAACAA
TGTATGTCATGACACATGATTCCATTGCAGTTGGTGAAGATGGTCCAACTCATGAACCAATTGAACAGTTAGCAAGTGTC
CGTTCAATGCCAAACTTGAACGTCATTCGTCCAGCAGATGGTAATGAAACCAATGCCGCATGGAAACGTGCCTTAGCAGA
AACAGATAAACCAACAATGCTAGTGTTAACACGACAAAACTTGCCAGTTCTTGAAGGAACAAAAGAGTTAGCAGAAGAAG
GTTTAAATAAGGGTGCTTATATCTTGTCAGAAGCCAAAGGCGAAATGGATGGTATCATCATTGCGACGGGATCTGAAGTG
AAATTAGCCATGGATACACAGGCTGCGCTAGCAGAAGAAGGAATCCATGTTCGTGTCGTATCAATGCCATCACAAAATAT
CTTTGATGTGCAAAGCGACGCTTATAAAGAAGAGATTTTACCAGCCGCAATCACAAAACGCTTGGCAATTGAAGCAGCAT
CAAGCTTTGGTTGGGCAAAATATGTAGGCTTAGCTGGCAAAACCTTAACCATTGACACATGGGGAGCTTCAGCACCAGGA
AATCGTATCTTTGAAGAATATGGTTTCACAACAGAAAATGCTACAGCCCTATACAAATCATTATAA

Protein sequence :
MTFDAVDQLAVNTVRTLSMDAIQKANSGHPGLPMGAAPMAYVLWNRFMTVNPKTSRNWTNRDRFVLSAGHGSAMLYSLLH
LAGYNLSIEDIKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGLAMAEAHLAAKYNKPGYNIVDHYTYALNGDG
DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEAIAKALEEAKAETQ
KPTIIEVKTIIGYGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTAEDFEVPAEVSKRFEEGIQTKGAQAEAAWNELFAAYE
KEYPELAADYKAAFANEPVSVDLAAHELGTSKASRVSSQEAIQQISEQVSSFWGGSADLSASNNTMVKVEKDFQPGQYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTMYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRALAETDKPTMLVLTRQNLPVLEGTKELAEEGLNKGAYILSEAKGEMDGIIIATGSEV
KLAMDTQAALAEEGIHVRVVSMPSQNIFDVQSDAYKEEILPAAITKRLAIEAASSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTTENATALYKSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-137 51
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-134 48