Gene Information

Name : nrdE (MCCL_0483)
Accession : YP_002559886.1
Strain : Macrococcus caseolyticus JCSC5402
Genome accession: NC_011999
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : -
Position : 512219 - 514324 bp
Length : 2106 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
GTGAATATCATACAAGAGAAACAGTACAATCATATTGAACTTAATAACCAGGTTACGAAACGTCGAGAAGATGGCTTCTT
TGATATTGATAAAGATCAAGAAGCACTTAAAGTTTACTTAGAAGAAATAAAAGATAAAACGATAACTTTTGACACACCGA
TTGCACGTCTTAAGTACCTCGTTGAACAAGATTTTTATTATGATTTATTTAATGAGTATAACGAAACAGATTTGAATGAT
ATTATCAAGTATGCACAAGACATTGAATTCAACTTTGCCAGCTATATGTCAGCAAGTAAATTCTTTAAAGATTACGCATT
GAAAACAAATGATAAACAGCAATATCTAGAAGATTATAAAGAGCATGTTATCATCGTAAGCCTATATTTAGCTAAAGGTG
ATGTAAATAAGGCGAAACAATTAATCTCTGCGATGATTGAGCAACGTTATCAACCAGCGACACCTACATTTTTAAATGCT
GGTCGTGCAAGACGCGGTGAGCTTGTATCTTGTTTCTTGCTAGAAGTAGATGATAGTTTAAATTCTATCAACTATATCGA
CTCAACTGCGAAACAATTATCTAAAATTGGTGGCGGTGTTGCAATCAACTTGTCAAAGTTACGTGCAAGAGGAGAAGCGA
TCAAAGGCATTAAAGGTGTAGCTAAAGGTGTATTACCTGTAGCTAAGGCGCTCGAAGGTGGATTTAGTTATGCAGACCAG
CTAGGACAACGTCCAGGTGCAGGCGCTGTATACTTAAACATCTTCCATTATGATGTGCTAGAGTTCTTAGATACGAAAAA
AGTAAATGCTGATGAGGACTTACGTTTATCGACGATTTCTACTGGACTTATCGTACCAAGTAAATTCTTTGATTTGGCGA
AAGAGGGCAAAGATTTCTTTATGTTTGCACCACATACAGTTGAACGTGAATATGGTTTAACGCTAGACGATCTGAACATT
GATGAAATGTATGACGAACTTGTGGCAAATCCAAATATTATGAAGAAATCTAAAGATGCGCGTGAAATGTTAAACTTGAT
TGCTCAAACGCAACTTCAGTCGGGTTATCCATACTTAATGTTTAAGGATAATGCGAACAAAGTGCATGCAAATTCGAATA
TCGGTCAGATTAAGATGAGCAATTTATGTACAGAGATCTTCCAGTTACAAGAAACATCCATTATTAATGATTATGGCACT
GAAGATGAAATCAAACGCGATATATCATGTAACTTAGGATCATTGAATATTGTGAATGTAATGGAATCTAAGAAATTTAA
AGATTCAGTACATACTGGTATGGATGCACTTACAACTGTAAGCGATGAAGCGGATATTAAAAATGCACCAGGTGTCGCGA
AAGCGAACCGTGAGTTACATTCGGTTGGTTTAGGGGTCATGAACCTGCATGGCTATTTAGCTAAAAACCAAATCGGTTAT
GAATCAGAGGAAGCGAAAGAATTTGCTGCGACGTTCTTTATGATGCTGAACTTCTATTCTTTACAACGTTCTATGGAAAT
CGCAATGGAACGTAACGAAACGTTTGCTGACTTTGAAAAATCAGATTATGCATCTGGTAAGTACTTTGATAAATACGTTG
CAACAGATTTTCGCCCGAAATCTGACAAAGTGACTGCATTATTTGAGGGTATCGACATGCCATCTCCGGAAGATTGGGCA
GACTTAAAGGATAAAGTAATGAAGAATGGTTTATTCCATGCGTATCGTTTAGCGATTGCGCCGACACAAAGCATTTCTTA
TGTACAAAATGCAACGAGTTCTGTAATGCCGATTGTTGACCAGATTGAGCGTAGAACGTATGGTAATGCCGAAACATTCT
ATCCTATGCCATTTTTATCACCTGAGACGATGTGGTTCTACAAATCAGCATTCAATACGGATCAAATGAAGTTGATTGAT
TTAATTGCAACGATTCAGGAACATATAGATCAGGGGATTAGTACAATCTTATTTGTAAATAGTGACATATCTACGAGAGA
GCTTGCAAGACTTTATGTTTATGCGCATCATAAAGGATTAAAGTCGCTTTACTACACAAGAAATAAATTATTAAGTGTAG
AAGAATGTACAAGCTGTGCAATTTAA

Protein sequence :
MNIIQEKQYNHIELNNQVTKRREDGFFDIDKDQEALKVYLEEIKDKTITFDTPIARLKYLVEQDFYYDLFNEYNETDLND
IIKYAQDIEFNFASYMSASKFFKDYALKTNDKQQYLEDYKEHVIIVSLYLAKGDVNKAKQLISAMIEQRYQPATPTFLNA
GRARRGELVSCFLLEVDDSLNSINYIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPVAKALEGGFSYADQ
LGQRPGAGAVYLNIFHYDVLEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFFMFAPHTVEREYGLTLDDLNI
DEMYDELVANPNIMKKSKDAREMLNLIAQTQLQSGYPYLMFKDNANKVHANSNIGQIKMSNLCTEIFQLQETSIINDYGT
EDEIKRDISCNLGSLNIVNVMESKKFKDSVHTGMDALTTVSDEADIKNAPGVAKANRELHSVGLGVMNLHGYLAKNQIGY
ESEEAKEFAATFFMMLNFYSLQRSMEIAMERNETFADFEKSDYASGKYFDKYVATDFRPKSDKVTALFEGIDMPSPEDWA
DLKDKVMKNGLFHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPETMWFYKSAFNTDQMKLID
LIATIQEHIDQGISTILFVNSDISTRELARLYVYAHHKGLKSLYYTRNKLLSVEECTSCAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 2e-140 43