Gene Information

Name : guaA (MCCL_1941)
Accession : YP_002561344.1
Strain : Macrococcus caseolyticus JCSC5402
Genome accession: NC_011999
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2082905 - 2084446 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAAATGGCATTTGAACAAGAGCTCATACTCGTTCTTGATTTTGGAAGTCAGTATAACCAGTTAATCACACGACGTAT
TCGTGAGATGGGTGTTTATTCAGAACTTCACGATCATGAAATTTCAATTGAAGAGATTAAAAAGATGAATCCTAAAGGAA
TCATTCTTTCAGGGGGACCAAACTCAGTTTATGAAGAAGGTTCGTTTACGGTAGATCCTGAAATCTTTAATTTAGGAGTA
CCTGTAATGGGGATTTGCTATGGTATGCAATTAATGACGAAATTACTAGGAGGTTCAGTAGAGCGTGCAAATGAACGTGA
GTACGGTAAAGCAGTCATTAAAGCAGAAACACATTCATTGTTTACAAAACTTCCAGAAGAACAAACAGTATGGATGAGTC
ATAGCGATAAAGTAATCAACCTACCTGAAGGTTTTAATGTCATTGCACATTCACCAAGCTGCAAATATGCAGCGATTGAG
AATCCTGAACGTAATTTATATGGGGTTCAATTCCATCCTGAAGTACGTCATTCTGAATACGGAAATGATTTATTACGTAA
CTTCATCCGTGAAATCTGTAAATGTACCGGTGAATGGACAATGGAAAACTTCATCGAAATCGAAATCGAGAAGATTCGCG
AAAAAGTTGGAGATAGAAAAGTTATTTGTGCGATGAGTGGTGGCGTAGATTCATCAGTTGTCGCAGTATTAATCCATAAA
GCAATCGGCGATCAGTTAACATGTATCTTCGTTGACCATGGTTTACTCCGTAAAGGTGAAGGCGACATGGTTATGAAACA
ATTCGGTGAAGGTTTCAACATGAATATTATTCGCGTTGACGCAAAAGAACGTTTTATGAGCAAGTTAGCTGGCGTATCAG
ATCCAGAACAAAAACGTAAAATTATCGGTAATGAGTTCGTATACTTATTCGATGAAGAAGCAGCGAAATTAAAAGATGCT
GATTTCCTAGCACAAGGTACACTTTATACAGATATTATTGAATCAGGTACGAAGACTGCACAAACAATTAAATCTCACCA
TAACGTTGGTGGATTACCTGAAGACATGCAGTTTGAATTAATCGAACCTGTGAATACATTATTTAAAGACGAAGTACGTG
CGTTAGGAATTGAATTAGGCATTCCTGAACACTTAGTATGGCGTCAACCATTCCCAGGTCCAGGACTTGGCATTCGTGTA
TTAGGTGAAATCACTGAAGAGAAATTAGAAATCGTACGTGAATCAGATGCGATTTTAAGAGAAGTGATTGCTGAAGAAGG
TCTCGAACGTGACATCTGGCAATACTTCACTGTATTACCTGATATCCGTTCGGTAGGTGTTATGGGAGATTACAGAACAT
ACGACTATACAGTCGGTGTTCGTGCCGTAACAAGTATCGATGGTATGACAAGTGACTTCGCTCGCATCGATTGGGAAGTC
CTTCAAAAAGTATCAAGCCGTATCGTAAACGAAGTAGACCATGTTAATCGCGTTGTCTATGACATTACATCTAAGCCACC
AAGCACGATTGAGTGGGAATAG

Protein sequence :
MEMAFEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTVDPEIFNLGV
PVMGICYGMQLMTKLLGGSVERANEREYGKAVIKAETHSLFTKLPEEQTVWMSHSDKVINLPEGFNVIAHSPSCKYAAIE
NPERNLYGVQFHPEVRHSEYGNDLLRNFIREICKCTGEWTMENFIEIEIEKIREKVGDRKVICAMSGGVDSSVVAVLIHK
AIGDQLTCIFVDHGLLRKGEGDMVMKQFGEGFNMNIIRVDAKERFMSKLAGVSDPEQKRKIIGNEFVYLFDEEAAKLKDA
DFLAQGTLYTDIIESGTKTAQTIKSHHNVGGLPEDMQFELIEPVNTLFKDEVRALGIELGIPEHLVWRQPFPGPGLGIRV
LGEITEEKLEIVRESDAILREVIAEEGLERDIWQYFTVLPDIRSVGVMGDYRTYDYTVGVRAVTSIDGMTSDFARIDWEV
LQKVSSRIVNEVDHVNRVVYDITSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 88
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 88
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 88
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-132 52