Gene Information

Name : leuS (MCCL_1435)
Accession : YP_002560838.1
Strain : Macrococcus caseolyticus JCSC5402
Genome accession: NC_011999
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1555756 - 1558164 bp
Length : 2409 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTTTAATCATCAAACAATTGAGAAGAAATGGCAGAAGTACTGGTTAGATAACCACACATTTAAAACGACTGAAGA
TAAGGATAAGAATTTCTATGCATTAGATATGTTCCCGTACCCATCAGGTGCTGGTCTTCACGTTGGACATCCTGAGGGCT
ACACAGCAACGGATATCATTTCTCGTTTTAAGCGTATGCAAGGTTATAACGTATTACATCCGATGGGGTGGGACGCATTC
GGACTGCCAGCAGAGCAATATGCAATCGATACAGGGAATGATCCGGCAGAATTCACCGAGAAGAATATTGCGACATTCAA
ACGTCAAATTCAAGAACTGGGCTTCAGCTATGACTGGGAGCGCGAAATTAATACGACAGACCCTGAGTATTATAAGTGGA
CACAGTGGATCTTCATACAGCTGTATAAAAAAGGTTTAGCATATGTGGATGAAGTAGCAGTGAACTGGTGCCCTGCTCTC
GGGACCGTATTATCAAATGAAGAAGTAATTGATGGTGTATCAGAGCGTGGTGGACACCCTGTGATTCGTAAACCAATGCG
TCAGTGGGTCCTTAAAATTACTGAATATGCAGATCGTTTACTGGAAGATCTAGAAGAGCTGGACTGGCCGGAATCTCTAA
AAGATATGCAGCGTAACTGGATTGGTCGCTCAGAAGGTGCTGAAGTTGCTTTCGAAGTTGAAAATTTAGACCATTCATTT
AAAGTATTTACAACACGTCCAGATACAATTTATGGTGCAACTTATGCGGTATTATCACCTGAGCATGAATTAGTTGCGGC
AATTACATCAGAAGAACAAGCAGAAGCGGTAAAAGCATATCAGGAACAGGCAGCAAGAAAATCTGACCTTGAACGAACTG
ATCTTGCGAAAGACAAGACAGGGGTCTTTACAGGAAGTTATGCAATCAATCCATTTAATGGAGAACGTATGCCGATCTGG
ATTTCTGATTACGTACTAGCTTCATATGGTACAGGTGCAATTATGGCAGTACCAGCACATGATGAGCGTGACTTTGAATT
TGCGAAACAGTTCGGATTAGACATTAAACCAGTGATTGAAGGTGGCGATAATACATCAGCTTACACAGGTGATGGTGCTC
ATATCAACTCAGGTGAACTTGATGGCCTGAACAAAGAGGAAGGAATCAGACGTGCAATCGAGCTGTTAGAAGCTAAAGGT
ATCGGTGAAAAGAAAGTATCTTACAAACTACGTGACTGGTTGTTCTCTCGTCAACGTTACTGGGGTGAACCAATTCCTGT
AATTACATGGGAAGATGGTTCGATGACAACTGTACCTGAAGAAGAATTACCACTGATGCTACCGAAGACAGAACACATCA
AGCCATCAGGGACAGGAGAATCACCACTTGCGAACATTGATGAATTTGTCAATGTCACAGATCCTGTTACAGGGATGAAA
GGGCGCCGTGAAACGAATACGATGCCACAATGGGCGGGTAGCTGCTGGTATTACTTACGTTACATCGATCCGAAGAATTC
TGACATGATCGCAGATCCTGAGCTTCTTAAAAAATGGTTACCGGTAGATTTATATATCGGTGGTGCAGAACACGCTGTGC
TTCATTTACTATATGCACGTTTCTGGCATAAGGTATTGTATGATCTAGGCGTTGTACATACGAAAGAACCATTCCAGAAA
CTATTCAACCAAGGGATGATTCTCGGTGAAGGAAACGAGAAGATGAGTAAATCAAAAGGGAATGTCGTGAACCCGGATGA
CGTCGTTGCAAGTCATGGAGCAGATACGCTACGTCTCTACGAAATGTTCATGGGACCACTTGATGCTTCAATCGCATGGA
GCACAAATGGATTAGATGGTGCACGTCGTTTCTTGGACCGTGTGTATCGTCTGCTTGTAAATGAAGATGGCACACTCTCT
GAGAAGATTACAGAACAACCAGTAGGATCTATGGAGAAAGTGTATCATCAAACTGTGAAGAAAGTAACGGATGACTATGA
AACATTAGGCTTCAATACAGCAATCTCACAGATGATGGTATTTATCAATGAAGGATACAAATCTGAACAATTAAACATCG
ACCACATCCGTGGGTTCGTAAAGTTATTGAATCCAATTGCACCACACATCACAGAAGAACTTTGGGAAAAACTTGGCGGT
ACGGAATCAATAACGTACGAAGCATGGCCGGTATATGACGAAAGTAAGCTTGTGGACAGCGAGGTTGAAATCGTCATTCA
AGTGAACGGTAAGCTTAAACAAAAAGCAACAATCGCGAAAGATATGGATAAATCAGAAATGGAAACATTTGCATTATCAC
TTGAAGCAGTGCAGACAGCGATTGAAGGCAAAACTGTAAGAAAAGTAATTGCTGTACCAAACAAACTTGTCAATATCGTG
GCAAACTAG

Protein sequence :
MSFNHQTIEKKWQKYWLDNHTFKTTEDKDKNFYALDMFPYPSGAGLHVGHPEGYTATDIISRFKRMQGYNVLHPMGWDAF
GLPAEQYAIDTGNDPAEFTEKNIATFKRQIQELGFSYDWEREINTTDPEYYKWTQWIFIQLYKKGLAYVDEVAVNWCPAL
GTVLSNEEVIDGVSERGGHPVIRKPMRQWVLKITEYADRLLEDLEELDWPESLKDMQRNWIGRSEGAEVAFEVENLDHSF
KVFTTRPDTIYGATYAVLSPEHELVAAITSEEQAEAVKAYQEQAARKSDLERTDLAKDKTGVFTGSYAINPFNGERMPIW
ISDYVLASYGTGAIMAVPAHDERDFEFAKQFGLDIKPVIEGGDNTSAYTGDGAHINSGELDGLNKEEGIRRAIELLEAKG
IGEKKVSYKLRDWLFSRQRYWGEPIPVITWEDGSMTTVPEEELPLMLPKTEHIKPSGTGESPLANIDEFVNVTDPVTGMK
GRRETNTMPQWAGSCWYYLRYIDPKNSDMIADPELLKKWLPVDLYIGGAEHAVLHLLYARFWHKVLYDLGVVHTKEPFQK
LFNQGMILGEGNEKMSKSKGNVVNPDDVVASHGADTLRLYEMFMGPLDASIAWSTNGLDGARRFLDRVYRLLVNEDGTLS
EKITEQPVGSMEKVYHQTVKKVTDDYETLGFNTAISQMMVFINEGYKSEQLNIDHIRGFVKLLNPIAPHITEELWEKLGG
TESITYEAWPVYDESKLVDSEVEIVIQVNGKLKQKATIAKDMDKSEMETFALSLEAVQTAIEGKTVRKVIAVPNKLVNIV
AN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67