Gene Information

Name : serS (MCCL_0013)
Accession : YP_002559416.1
Strain : Macrococcus caseolyticus JCSC5402
Genome accession: NC_011999
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 16258 - 17529 bp
Length : 1272 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACATTAAATTATTTAGAACAGAACCAGAATTCGTTAAGAAAAAATTAGAAATGCGTGCGATTGATACTTCCAT
CGTTGATGAAATATTAGAGCTTGATATAGCGGCGCGTGAGCTTACAGCAAGAACTGAAGAATTAAAAGCAAAACGTAATA
AAACGAGCGAAGAAATTGCACAGAAAAAACGTAATAAAGAAAATGCAGATGATGCAATTAAAGCAATGCGTGAAGTAGGT
GAAGAAATAAAGCGTATTGATACGGAGTTGAACGAAGTATCTCAGACGTTGAAGGATAAACTTGTACGTTTGCCGAACTT
AGTAAGCGATGAAACACCATTTGGCAAAGATGAGGATGAAAACGTTGAAGTCAAGAAATGGGGAACACCACGTACATTTG
ATTTCGAAGCAAAAGCGCATTGGGATATCGTCGAAAATTTAAAAATGGCTGATTTTGAGCGTGCTGCTAAAGTTTCAGGT
GCACGTTTCGCATTCTTAACTAAAGATGGTGCGCGTCTAGAACGTGCATTAATGAACTTTATGTTAGATACACATCGTGC
AAATGGATATGAAGAAATGGTGACACCACAACTGGTAAATGCTGCTTCTATGTTCGGTACAGGACAACTTCCTAAGTTTG
AAGAGGACTTATTCAAAGTTGAAAAAGAAGGTCTATATACAATTCCAACTTCAGAAGTGCCATTAACGAACTTCTATCGT
GATGAAATTTTAACCAATGATATGTTACCTACGAAATTTACAGCTATGACAGCATGTTTCAGAAGTGAAGCAGGTTCAGC
AGGCCGTGATACACGTGGATTAATTCGTATGCATCAATTTAACAAAGTCGAAATGGTACGCTTTGAACGTCCTGAAGATT
CTTATGCTGCGTTAGAAGATATGACACGTTCAGCTGAAAGCATTCTGGAGAAATTAAATATTCCTTATCGTACGATCGCT
TTATGTTCAGGAGATATCGGATTTGGCGCTGCAAAAACTTATGATGTTGAAGTATGGTTGCCAAGTTATGATGCCTATAA
AGAAATTAGCTCATGTTCAAATATGACAGACTTTCAGGCACGACGTGCAAATATTCGTTTCAAGCGCGATAAAAATGCAA
AAGCTGAACTTGTAAATACACTGAATGGTTCAGGACTAGCTGTAGGACGTACTTTTGCTGCAGTAGTTGAAAATTATCAA
AATGAGGATGGATCTATCACAGTTCCAGAAGTACTCGTTCCATATATGGGTGGACAAACTGTAATTAAATAA

Protein sequence :
MLDIKLFRTEPEFVKKKLEMRAIDTSIVDEILELDIAARELTARTEELKAKRNKTSEEIAQKKRNKENADDAIKAMREVG
EEIKRIDTELNEVSQTLKDKLVRLPNLVSDETPFGKDEDENVEVKKWGTPRTFDFEAKAHWDIVENLKMADFERAAKVSG
ARFAFLTKDGARLERALMNFMLDTHRANGYEEMVTPQLVNAASMFGTGQLPKFEEDLFKVEKEGLYTIPTSEVPLTNFYR
DEILTNDMLPTKFTAMTACFRSEAGSAGRDTRGLIRMHQFNKVEMVRFERPEDSYAALEDMTRSAESILEKLNIPYRTIA
LCSGDIGFGAAKTYDVEVWLPSYDAYKEISSCSNMTDFQARRANIRFKRDKNAKAELVNTLNGSGLAVGRTFAAVVENYQ
NEDGSITVPEVLVPYMGGQTVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-124 60