Gene Information

Name : MCCL_plsB0023 (MCCL_plsB0023)
Accession : YP_002559354.1
Strain :
Genome accession: NC_011996
Putative virulence/resistance : Resistance
Product : penicillin-binding protein 2' homolog
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0768
EC number : -
Position : 25508 - 27532 bp
Length : 2025 bp
Strand : +
Note : -

DNA sequence : 
ATGAAAAATAAAGCTTTAGCAATTTTAATTATATGTATTTGCCTTTTAATAGCATATAATTTTGTGAAAAAAGATGAAGT
TGATAAAATATTTGATGCTATTGAATTAAGGGATTCGGAATATCTGAATGAACATGCGACATTCTTATCTAAAAGTCTTT
ACGACAAAGATCAGAGATATAAAAGAATGGATAAGATTGATGCTTCTCTTGGTATTAAAGAAGTGAAAGTTAGTAATGTA
CGACTCGTGCAAAAGAAAAAAAATAAACGTCAATATAGTGCAAATTTAAATTTTAGAACTAAATATGGTAATTTTTCTAG
AGAAGGGAACTATTCTTTTGAAAAGGATGAAATAACAAAAAAATGGCTTTTGGATTGGTCACCTGAGGTTATAATACCGG
GATTGACTGATAGAAATCAAATCAGTATAGAAACCTTGGAATCTTTCAGAGGGAAAATACTAGACAGAAACGGGATTGAT
ATAGCGAAAGACGGAATTCATTACGAAGTTGGAATAGATATTAAAAATTTAAATAAAAAAAATAAGAAAAATATTTCAAA
ATTGTTATCAATAAGTGAATCGACACTAAATAAAAAGTTAAAACAAACATGGGTAAAAGAAGGTGTTTTTTTACCTTTAA
AATCGTACATAGAGTTGGATGATGAACTTAAATTGGGTATCCAAAAATATCATTTGACGGTTAATCAAACAAAAGGTAGG
GTTTATCCATTAAGAGAAGCAACAGTACATCTTTTAGGGTATGTTGGAGAAATTAATGCTGAAGAATTAAAGAATAAAAA
GTTTAAGGATTATGATGAACACTCAATCGTAGGAAAAAGTGGTATCGAACTACAATATGATAAACAATTGCAAAATAAAG
ATGGTTATAAAGTTGTCATAACTAGTGATGATGCATTAAATAATGATGAAGATGTCTTGTTAGAAAAGAAACCAAAAAAT
GGACAGGACATTATATTAACAATTGATAGCAAAGTACAAAGAAGTATATATAGTCATTTAAAAGAAGATAATGGTTCAGG
AGTAGCCATGAATCCTAAAACTGGTGAATTATTAGCTTTAGTTAGTTATCCTGCATATGACCCCTATGAGTTTATGTTCG
GCATTTCCGACGAAAACTACAAAAAGATAGTTAATGATAAGAAAGAGCCCCTGTTAAATAAATTTCAGACAACCTCTTCC
CCAGGATCTACTCAGAAATTAATAACATCTATCATAGGTTTGAAAAATGGGACTATAGACGCATCAACCAGCTACAACAT
AGTAACTAAGGGATGGCAGAGAAATTCTTCATGGGGAGGATATGAAGTTACAAGGTTTGAGGAAGTTAATGGAGATATTG
ATTTAGAAAAAGCGATAGCACATTCTGATAATATATTTTTTGCAAGAGCTACCCTCGATATGGGTTCCGAAAAATTTATT
AAGGGCATGAAAGCTTTAGACATTGGGAGAAATATTCCTTCTGATTATTATTTTCAAAAAGGACAAATTGCAAATCCAGA
AAGTTTAAAAAATAATTTTAAAAATGAAATATTACTAGCTGATTCAGGATATGGCCAGGGAGAAATACTTATAAGTCCAG
TACAAATATTATCTATTTATAGTTCTTTAATTAATGAAGGTAAAATGATGAAACCTAAATTATTTGAAACAACAAAAGAA
GATATTTGGAAAAATCATATTATTTCAAAAGATGACGTAGATATATTAACAAGAAGCATGAGAAAAGTAGTTACTGGGAC
ACATAGATTGGATGCAGAAAGAAATTATGCACAGTTTGCTGGAAAAACTGGCACTGCAGAATTGAAAACCTCTAGAGAAG
AGGGGTTAGGAGCTCAAATCGGTTGGTTTGTTGGATATGATCAAAATAATCCCAATATGATGTTAGGTATAAGTGTGAAG
AATGTAGAGAATAAAGGTATGTCGAGTTATAATGCAAGAAAGTTTGCCGAGATAATGGATGAATTATATGAAAATGGAAC
GAAAAAATATGAAATAGATAGGTGA

Protein sequence : 
MKNKALAILIICICLLIAYNFVKKDEVDKIFDAIELRDSEYLNEHATFLSKSLYDKDQRYKRMDKIDASLGIKEVKVSNV
RLVQKKKNKRQYSANLNFRTKYGNFSREGNYSFEKDEITKKWLLDWSPEVIIPGLTDRNQISIETLESFRGKILDRNGID
IAKDGIHYEVGIDIKNLNKKNKKNISKLLSISESTLNKKLKQTWVKEGVFLPLKSYIELDDELKLGIQKYHLTVNQTKGR
VYPLREATVHLLGYVGEINAEELKNKKFKDYDEHSIVGKSGIELQYDKQLQNKDGYKVVITSDDALNNDEDVLLEKKPKN
GQDIILTIDSKVQRSIYSHLKEDNGSGVAMNPKTGELLALVSYPAYDPYEFMFGISDENYKKIVNDKKEPLLNKFQTTSS
PGSTQKLITSIIGLKNGTIDASTSYNIVTKGWQRNSSWGGYEVTRFEEVNGDIDLEKAIAHSDNIFFARATLDMGSEKFI
KGMKALDIGRNIPSDYYFQKGQIANPESLKNNFKNEILLADSGYGQGEILISPVQILSIYSSLINEGKMMKPKLFETTKE
DIWKNHIISKDDVDILTRSMRKVVTGTHRLDAERNYAQFAGKTGTAELKTSREEGLGAQIGWFVGYDQNNPNMMLGISVK
NVENKGMSSYNARKFAEIMDELYENGTKKYEIDR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mecA BAA86650.1 penicillin-binding protein 2' Not tested Type-I SCCmec Protein 1e-154 53
mecA YP_190062.1 penicillin-binding protein 2' Not tested Type-II SCCmec Protein 2e-154 53
mecA BAC57478.1 penicillin-binding protein 2' Not tested Type-IIIinv SCCmec Protein 1e-154 53
mecA YP_184944.1 penicillin-binding protein 2' Not tested Type-I SCCmec Protein 2e-154 53
mecA BAC67568.1 penicillin-binding protein 2' Not tested Type-IVc SCCmec Protein 1e-154 53
SAPIG0042 YP_005732852.1 penicillin-binding protein 3 (pbp 3) (pspb20) Not tested Type-V SCCmec Protein 9e-155 53
mecA YP_039515.1 penicillin-binding protein 2 prime Not tested Type-II SCCmec Protein 2e-154 53
mecA BAD24826.1 penicillin-binding protein 2' Not tested Type-V SCCmec Protein 7e-155 53
mecA YP_252006.1 penicillin binding protein 2 prime Not tested SCCmec Protein 9e-155 53
SAMSHR1132_00320 YP_005324556.1 penicillin-binding protein 2 prime Not tested Type-IIIinv SCCmec Protein 2e-154 53
unnamed ACL99850.1 penicillin binding protein 2a Not tested Type-V SCCmec Protein 7e-155 53
mecA BAB72113.1 penicillin-binding protein 2' Not tested Type-IVa SCCmec Protein 1e-154 53
mecA NP_644846.1 penicillin binding protein 2 prime Not tested Type-IV SCCmec Protein 2e-154 53
mecA BAB72132.1 penicillin-binding protein 2' Not tested Type-IVb SCCmec Protein 1e-154 53
mecA NP_370565.1 penicillin binding protein 2 prime Not tested Type-II SCCmec Protein 2e-154 53
mecA BAA82220.1 penicillin binding protein 2' Not tested Type-II SCCmec Protein 1e-154 53
mecA NP_373278.1 penicillin binding protein 2 prime Not tested Type-II SCCmec Protein 2e-154 53
mecA BAB47623.1 penicillin-binding protein 2' Not tested Type-III SCCmec Protein 1e-154 53
mecA YP_492752.1 penicillin-binding protein 2' Not tested Type-IV SCCmec Protein 2e-154 53
mecA BAG06200.1 penicillin-binding protein 2' Not tested Type-VII SCCmec Protein 7e-155 53
mecA YP_005754041.1 beta-lactam-inducible penicillin-binding protein Not tested Type-XI SCCmec Protein 3e-151 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog AB096217.gene.p01 Protein 7e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_002758.1120001.p0 Protein 9e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_003923.1004781.p0 Protein 9e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_010079.5776902.p0 Protein 9e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_007793.3913904.p0 Protein 9e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_002951.3236763.p0 Protein 7e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_002745.1122812.p0 Protein 9e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_009782.5559258.p0 Protein 9e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog NC_002952.2861157.p0 Protein 9e-155 53
MCCL_plsB0023 YP_002559354.1 penicillin-binding protein 2' homolog FR823292.1.gene3.p01 Protein 2e-151 51