Gene Information

Name : LF82_550 (LF82_550)
Accession : YP_002558393.1
Strain : Escherichia coli LF82
Genome accession: NC_011993
Putative virulence/resistance : Virulence
Product : Outer membrane usher protein lpfC precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3757358 - 3759889 bp
Length : 2532 bp
Strand : -
Note : corresponding to LF82_p550 in publication : Miquel et al., PLoS One; 55989; ED1a; IAI1

DNA sequence :
ATGCATTGGATGCATTTACCTCTTGATCACTACAGAGCGCATTTTTCTTTCTCACTGTTGGCATTAACTATTGCCAGCGC
GTTACCTGCGTACGGCGGAAAATTCAACCCTAAATTTCTTGAAAATGTTCAGGGTATTGATCAACACGTCGATTTGTCAG
TTTACGACTCTCCTGTCGGCCAGCAAATACCCGGTAAATATCGGGTATTTGTGTTTGTAAACGAAGAAAAAATGGCTTCC
CGGACGCTGGATTTTAGTACTGCCAGCGAAGCACAACGCAAAGCCAGCGGCGAGTCGCTTATGCCTTGCCTTAGCCGTGT
TCAACTGGAAGAAATGGGCGTGCGCATCGACAGCTTTCCGGCACTGAAGATATTGCCACCGGAAGCCTGCGTAGCGTTTG
ATGAAATCATTCCCCAGGCCACCAGTCGTTTTGATTTTAATACTCAGACGTTGCATCTTACCTTTCCACAGGCAGCAATG
ATGATGACCGCTCGTGGCACGGTTGATCCTTCTCGCTGGGACGAAGGAATACCTGCGCTGTTACTGGACTACAGCTTTAG
TGGCAGCAATGGTCGCAACGAAGGTTCCGGTTCATCTCCAGATTCGACCAGTGACAGTTATTACCTGAACTTGCGCAGCG
GTTTGAACGTGGGGCCGTGGCGTTTACGTAATAACAGTATCTGGAACCGTACCGATGGCAAAAATCAATGGGATAACGTT
GGTACATCGTTAAACCGGGCGATTATTCCACTCAAGTCACAGATAACATTGGGTGATACCGCCACGCCTGGCGAGATTTT
TGATAGCGTACAAATGCGCGGGACATTATTGGCATCCGACGATGAAATGTTGCCGGATAGCCAGCGTGGCTTTGCTCCGG
TGGTGCGTGGCATCGCCAAAAGTAACGCTGAAGTGAGTATCGAACAGAACGGATATGTTATTTATCGTACCTTTGTTCAG
CCGGGCGCATTTGAGATTAACGATCTCTACGCAACCTCCGGCAGCGGTGACTTGACGGTGATCATTAAAGAATCTGACGG
AAGTGAACAACGTTTTATTCAACCATTTTCGGCAGTGGCGATTTTCCAGCGTGAAGGGTATCTGAAATACAGCCTTGCTG
CCGGTGAGTATCGTGCCGGTAATTACGACAGCGGTAAACCGCGATTCGGGCAATTTACTGCCATGTACGGCTTGCCGTGG
GGAATGACCGCCTATGGTGGTGCGTTGCTATCGGCAGACTACAACGCTTTAGCTCTGGGGCTGGGGAAGAACTTCGGCAC
CATTGGTGCGGTATCGGTGGATGTCACCCAGGCGAAAAGTCAGTTACGCAACAATGAAAAAGATGAAGGGCAGTCTTATC
GTTTCCTCTATTCGAAAAGTTTTGAGGGCGGTACCGACCTGCGTCTGTTGGGCTACAAGTACTCAACCAGCGGTTATTAC
ACCTTCCAGGAAGCGACCGATGTCCGTAGTGACGCCGACAGTGACTATCGGCGTTATCATAAGCGCAGCCAGATACAAGG
TAACATCACTCAGCAACTGGGAGACTACGGTTCTGTTTACTTCAATATGACGCAGCAGGATTACTGGAACGTTGATGGTA
AGGAGAACTCCTTAAGCGCTGGTTATCACGGTCATATTGGTCGTGTGAATTACAGTATCGCCTATACCTGGACGAGAAGC
CCTGAATGGGATGAAGACGATCGACTGTGGTCATTTAGCCTCTCAATACCGCTGGGTGGCGCATGGGGCAGTTATCGTAT
GACCACCGACCAGAACGGCAAGACGTCACAACAGGCCTCTGTCAGCGGCACATTACTGGAAGATCGTAACTTGAACTATA
ACGTTCAGCAGGGTTATACCAGTAATGGGGTTGGCAACAGTGGTAGTGTCAACATGGGTTATATGGGAGGTTCTGGCAAC
ATTGACGTGGGTTATAACTATTCCAAAGATAACCAACAAGTTAACTATGGTGTGCGTGGTGGAGTCATTGTTCACAGTGA
AGGTATCACTCTCTCGCAACCCTTGGGTGAAAGTCTGGCAATTGTTTCTGCGCCGGGTGCGCGTGGTGGACATGTAGTAA
ATAGCAGCGGCGTTGAAGTTGACTGGATGGGCAACGCAGTGGTGCCGTATCTCACGCCATATCGTGAAACCATTGTGGAA
TTGCGCAGCGACACGTTAGGGCAAAACGTTGAATTACAGGAAGCGTTTCAGAAAGTCGTTCCAACGCGTGGGGCGATAGT
CCGTTCCCGCTTTGATACGCGTGTCGGTTATCGTGTGCTGATGAGTTTGAAACGGGCGAATGGCAACGCAGTACCGTTTG
GTGCTACCGCAGCGTTAAGTGATGAGAGCAAACCTGCCAGCAGCATTGTGGGTGAAGAAGGACAGCTTTATATCAGCGGG
ATGCCAGAAGAGGGCGAATTGCAGGTGAGCTGGGGGCACGAGCAGGCGCAACGTTGCCGCGTGCCATTCCGCTTGCCAGA
GAAAAAGGATAATTCGGGTATCGTGATGGTTAATGCGGTATGCGATAAATAA

Protein sequence :
MHWMHLPLDHYRAHFSFSLLALTIASALPAYGGKFNPKFLENVQGIDQHVDLSVYDSPVGQQIPGKYRVFVFVNEEKMAS
RTLDFSTASEAQRKASGESLMPCLSRVQLEEMGVRIDSFPALKILPPEACVAFDEIIPQATSRFDFNTQTLHLTFPQAAM
MMTARGTVDPSRWDEGIPALLLDYSFSGSNGRNEGSGSSPDSTSDSYYLNLRSGLNVGPWRLRNNSIWNRTDGKNQWDNV
GTSLNRAIIPLKSQITLGDTATPGEIFDSVQMRGTLLASDDEMLPDSQRGFAPVVRGIAKSNAEVSIEQNGYVIYRTFVQ
PGAFEINDLYATSGSGDLTVIIKESDGSEQRFIQPFSAVAIFQREGYLKYSLAAGEYRAGNYDSGKPRFGQFTAMYGLPW
GMTAYGGALLSADYNALALGLGKNFGTIGAVSVDVTQAKSQLRNNEKDEGQSYRFLYSKSFEGGTDLRLLGYKYSTSGYY
TFQEATDVRSDADSDYRRYHKRSQIQGNITQQLGDYGSVYFNMTQQDYWNVDGKENSLSAGYHGHIGRVNYSIAYTWTRS
PEWDEDDRLWSFSLSIPLGGAWGSYRMTTDQNGKTSQQASVSGTLLEDRNLNYNVQQGYTSNGVGNSGSVNMGYMGGSGN
IDVGYNYSKDNQQVNYGVRGGVIVHSEGITLSQPLGESLAIVSAPGARGGHVVNSSGVEVDWMGNAVVPYLTPYRETIVE
LRSDTLGQNVELQEAFQKVVPTRGAIVRSRFDTRVGYRVLMSLKRANGNAVPFGATAALSDESKPASSIVGEEGQLYISG
MPEEGELQVSWGHEQAQRCRVPFRLPEKKDNSGIVMVNAVCDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-157 44
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 3e-136 41
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 4e-158 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LF82_550 YP_002558393.1 Outer membrane usher protein lpfC precursor VFG0454 Protein 0.0 74
LF82_550 YP_002558393.1 Outer membrane usher protein lpfC precursor VFG0876 Protein 2e-162 44
LF82_550 YP_002558393.1 Outer membrane usher protein lpfC precursor VFG0446 Protein 5e-148 41
LF82_550 YP_002558393.1 Outer membrane usher protein lpfC precursor VFG1645 Protein 2e-158 41
LF82_550 YP_002558393.1 Outer membrane usher protein lpfC precursor VFG0912 Protein 3e-158 41