Gene Information

Name : LF82_465 (LF82_465)
Accession : YP_002557800.1
Strain : Escherichia coli LF82
Genome accession: NC_011993
Putative virulence/resistance : Virulence
Product : KpsC protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3116094 - 3118121 bp
Length : 2028 bp
Strand : +
Note : corresponding to LF82_p465 in publication : Miquel et al., PLoS One; 536; APEC_01; CFT073; ED1a; IAI39; S88; SMS_3_5; UMN026; UTI89

DNA sequence :
ATGATTGGCATTTACTCGCCTGGCATCTGGCGTATTCCGCATCTGGAGAAATTTCTGGCGCAACCGTGCCAGAAACTTTC
TCTGCTGCGCCCTGTTCCGCAAGAAGTTGATGCTATCGCCGTGTGGGGACATCGTCCCAGCGCGGCGAAACCAGTCGCCA
TCGCCAAAGCAGCGGGAAAACCCGTCATTCGTCTGGAAGATGGATTTGTGCGTTCGCTGGATCTTGGCGTCAATGGCGAG
CCGCCGCTTTCTCTGGTGGTGGATGATTGTGGCATTTACTACGATGCCAGCAAGCCTTCAGCACTGGAGAAACTGGTACA
GGATAAAGCCGGAAATACAGCTCTGATAAGCCAGGCCAGAGAAGCGATGCACACCATCGTGACCGGGGATTTGTCGAAAT
ATAACCTGGCACCTGCGTTTGTGGCTGATGAGTCAGAACGTTCAGACATCGTTCTGGTTGTCGATCAGACATTTAATGAT
ATGTCAGTGACGTATGGCAATGCTGGCCCGCATGAGTTTGCTGCCATGCTGGAAGCCGCGATGGCGGAAAATCCTCAAGC
CGAAATTTGGGTGAAGGTGCACCCAGATGTACTGGAAGGAAAGAAAACAGGCTATTTCGCTGATCTGCGCGCCACGCAAC
GAGTACGTTTGATTGCCGAGAATGTCAGCCCGCAGTCGCTGTTGCGACACGTTTCCCGGGTTTACGTCGTGACCTCCCAA
TACGGCTTTGAAGCCTTGCTGGCAGGAAAACCAGTAACATGTTTCGGCCAGCCCTGGTATGCAAGCTGGGGCTTAACCGA
CGATCGCCATCCGCAGTCCGCTTTGTTATCTGCCCGACGCGGTTCTGCCACGCTGGAGGAACTTTTTGCCGCTGCATACC
TGCGTTACTGTCGCTATATCGATCCGCAAACGGGAGAAGTAAGCAATCTATTTACCGTGCTGCAATGGCTGCAATTACAA
CGTCGGCATCTGCAACAGCGTAATGGTTATTTATGGGCGCCAGGCTTAACGCTGTGGAAGTCAGCGATCCTGAAACCTTT
CTTGCAAACGGCAACAAACCGGCTGAGTTTTTCTCGTCGCTGTACTGCGGCGAGCGCCTGCGTGGTATGGGGTGTAAAGG
GAGAACAGCAATGGCGAGCCGAAGCGCAGCGAAAATCACTGCCGTTATGGCGAATGGAAGATGGTTTTCTGCGTTCATCC
GGACTTGGCTCTGACCTGCTGCCGCCGCTATCGCTGGTGCTGGATAAACGCGGTATTTACTATGACGCCACGCGCCCCAG
CGATCTGGAAGTGCTGCTGAATCATAGCCAGCTAACGCTGGCGCAGAAGATGCGAGCTGAAAAATTACGCCAGCGACTGG
TTGAAAGCAAACTGAGTAAGTACAACCTGGGAGCCGATTTCTCTCTACCAGCCGAAGCCAAAGATAAAAAAGTTATCCTG
GTGCCGGGTCAGGTAGAAGACGATGCCTCAATTAAAACCGGCACCGTTTCTATTAAGAGCAACCTTGAGTTATTACGCAC
AGTACGCGAGCGCAATCCGCACGCTTACATTATTTATAAACCGCACCCGGATGTACTGGTGGGGAATCGCAAGGGCAATA
TTCCGGCAGAACTAATTGCTGAACTCGCTGATTATCAGGCACTGGATGCAGATATTATTCAATGCATCCAGCGCGCAGAT
GAAGTGCACACCATGACATCATTGTCCGGGTTTGAAGCGTTATTACATGGCAAGCAAGTTCATTGTTACGGCCTGCCCTT
CTATGCCGGTTGGGGTTTAACCGTTGATGAACATCATTGCCCGCGCCGCGAGCGCAGATTAACGATAGCAGACTTGATCT
ATCAGGCGTTGATTGTTTACCCAACATATATTCACCCAACACGGCTACAGCCTATTACGGTTGAGGAAGCTGCGGAATAT
TTAATCCAGACGCCGCGTAAGCCGATGTTTATTACCCGAAAAAAAGCGGGGCGGGTAATACGCTATTGCCGCAAATTAAT
TATGTTCTGCAAGGTCAGATTTGGCTAA

Protein sequence :
MIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVDAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGE
PPLSLVVDDCGIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDLSKYNLAPAFVADESERSDIVLVVDQTFND
MSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFADLRATQRVRLIAENVSPQSLLRHVSRVYVVTSQ
YGFEALLAGKPVTCFGQPWYASWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSNLFTVLQWLQLQ
RRHLQQRNGYLWAPGLTLWKSAILKPFLQTATNRLSFSRRCTAASACVVWGVKGEQQWRAEAQRKSLPLWRMEDGFLRSS
GLGSDLLPPLSLVLDKRGIYYDATRPSDLEVLLNHSQLTLAQKMRAEKLRQRLVESKLSKYNLGADFSLPAEAKDKKVIL
VPGQVEDDASIKTGTVSIKSNLELLRTVRERNPHAYIIYKPHPDVLVGNRKGNIPAELIAELADYQALDADIIQCIQRAD
EVHTMTSLSGFEALLHGKQVHCYGLPFYAGWGLTVDEHHCPRRERRLTIADLIYQALIVYPTYIHPTRLQPITVEEAAEY
LIQTPRKPMFITRKKAGRVIRYCRKLIMFCKVRFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 0.0 98
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 0.0 98
kpsC CAE85214.1 KpsC protein Virulence PAI V 536 Protein 2e-176 94
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 1e-127 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LF82_465 YP_002557800.1 KpsC protein VFG0259 Protein 4e-128 51
LF82_465 YP_002557800.1 KpsC protein VFG0692 Protein 2e-117 47
LF82_465 YP_002557800.1 KpsC protein VFG0704 Protein 6e-105 47