Gene Information

Name : lysS (Dtpsy_2603)
Accession : YP_002554038.1
Strain : Acidovorax ebreus TPSY
Genome accession: NC_011992
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 2765793 - 2767340 bp
Length : 1548 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCCACTGAAGCCACTCCCGCACCAGCCCCCCAGGACGAAAACCAACTCATCGCCGAACGCCGTGAAAAGCTCAAGGC
TCTGCGCGAGAACCAGGCCCAGGGTCAAGGCGTGGCATTTCCCAACGACTACAAGCCCCAGCACCATGCCGCAGTGCTGC
AGCAGCAGTACGGCACATTGGATGGAGAAGCGCTCGAAGCGCAGGCGATCACGGTGAGCGTGGCCGGCCGCATGATGCTC
AAGCGCGTCATGGGTAAGGCCAGCTTCGCGACCCTGCAGGATGGATCGCTGGGTGACACCGGCGGGCGCATCCAGCTCTA
CGTGACACGCGATGCCATTGGCGAAGAAGCCTATTCCGACTTCAAGCGCTGGGACCTCGGTGACATCCTGGGTGCCGAAG
GCACGCTGATGAAGACCAAGACCGGCGAGCTATCGGTCAAGGTGTCGCGCCTGCGCCTGCTCACCAAGAGCCTGCGCCCC
ATGCCCGACAAGTTCCACGGTGTAGCCGACCAGGAGGTCAAGTACCGCCAGCGCTACGTGGACCTGATGACCGACGAGGC
CGCGCGCCGGCGCTTCGTCGCGCGCAGCAAGGCTGTGGGCAGCATCCGTTCTTTCATGATGGAGCACGGCTTCCTGGAAG
TGGAAACGCCCATGCTGCACCCCATTCCCGGCGGCGCCAACGCCAAGCCCTTCGTCACCCACCACAATGCGTTGGAGCAG
GAGATGTTCCTGCGCATCGCGCCCGAGCTGTACCTCAAGCGCCTGATCGTCGGCGGCTTCGAGCGCGTGTTCGAGATCAA
CCGCAACTTCCGCAACGAAGGCATCTCGGTGCGCCACAACCCCGAGTTCACGATGATGGAGTTTTATGCGGCCTACTGGA
ACTACCGCGATCTGATGGATTTCACCGAGGCGCTGGTGCGCGATGCCGCACTCAAGGCCACGGGCACGCTGCAGCTCACC
TACGGTGGCCGCGCGGTGGATCTGGCCCAGCCCTTCCAGCGCCTCACGATCCGCGAGGCCATCTACCAGCACACCGAGGC
CGGCGCACATGTGGACGATGCCGCCTGGCTCATCAGCGCGCTCAAGAAACTGGGCATGACCGAGGAGAAGGACCGCCTGT
CCATCCGGACCCTCGCCAGCCTGCAGGTGCTCTACTTCGAGGAAGAGGTGGAGGACAAGCTCTGGCAGCCAACCTTCATC
ATGGAGCACCCGACCGAGATCAGCCCTCTGGCGCGCGCCAACGACCTGCGCCCCGAGGTGACGGAGCGCTTCGAGCTCTA
CATCACCGGCCGCGAGTTCGGCAATGGCTTCTCGGAGCTGAACGACGCCGAAGACCAGGCCGCCCGCTTTCATGCGCAGG
TGGCTGCCAAGGACGCGGGCGATGACGAGGCCATGTTCTTTGACCACGACTTCGTACGTGCGCTGGAATACGGCATGCCG
CCCACAGGTGGTTGCGGCATCGGCATCGACCGGCTGATGATGCTGCTCACCGACAGCCCGAGCATCCGTGACGTGATCCT
GTTTCCGGCCCTGCGGCGCGAGCACTGA

Protein sequence :
MSTEATPAPAPQDENQLIAERREKLKALRENQAQGQGVAFPNDYKPQHHAAVLQQQYGTLDGEALEAQAITVSVAGRMML
KRVMGKASFATLQDGSLGDTGGRIQLYVTRDAIGEEAYSDFKRWDLGDILGAEGTLMKTKTGELSVKVSRLRLLTKSLRP
MPDKFHGVADQEVKYRQRYVDLMTDEAARRRFVARSKAVGSIRSFMMEHGFLEVETPMLHPIPGGANAKPFVTHHNALEQ
EMFLRIAPELYLKRLIVGGFERVFEINRNFRNEGISVRHNPEFTMMEFYAAYWNYRDLMDFTEALVRDAALKATGTLQLT
YGGRAVDLAQPFQRLTIREAIYQHTEAGAHVDDAAWLISALKKLGMTEEKDRLSIRTLASLQVLYFEEEVEDKLWQPTFI
MEHPTEISPLARANDLRPEVTERFELYITGREFGNGFSELNDAEDQAARFHAQVAAKDAGDDEAMFFDHDFVRALEYGMP
PTGGCGIGIDRLMMLLTDSPSIRDVILFPALRREH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-134 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002554038.1 lysyl-tRNA synthetase VFG1668 Protein 2e-134 55