Gene Information

Name : hemC (Dtpsy_2377)
Accession : YP_002553814.1
Strain : Acidovorax ebreus TPSY
Genome accession: NC_011992
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2530441 - 2531373 bp
Length : 933 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGACCACTCCCTCCCCCTCGCTTCCTTCCATCGTGATCGCCACGCGCGAAAGCCAACTCGCGCTCTGGCAGGCCGAGCA
TGTGCAGTCCTTGCTGCGCGCGCGCGGCCACGCCGTGGCGCTGCTGGGCATGACCACGCGCGGCGACCAGATCCTGGACC
GCACGCTGTCCAAGGTGGGCGGCAAGGGCCTGTTCGTGAAGGAGCTGGAAGTGGCGCTGGAGGAAGGCCGCGCCGACATC
GCAGTGCATTCGCTCAAGGACGTTCCCATGGAGCTGCCCCAGGGCTTCGCCCTGGCCTGTGTGATGGAGCGCGAGGACCC
GCGCGACGCCTTCGTGTCGCCCGGCTACGCATCGCTGGACGAGCTGCCCCACGGTGCGGTGGTGGGCACGTCCAGCCTGC
GCCGCCAGGTGCTGCTGCAAGCGCTGCGCCCCGACCTGCAGATCGAGCCGCTGCGCGGCAACGTGCAGACGCGCTTGCGC
AAGCTGGACGAGGGCCAGTACGCGGCCATCGTGCTCGCGGCCGCAGGCCTGAAGCGCCTGGGCCTGCACGAGCGCATCCG
CGCCGTGTTCACGCCCGAGCAGATGCTGCCCGCCGCCGGCCAGGGCGCGTTGGGCATCGAGATCCGCGGCGACCGCCACG
ACCTGCGCGAGGCGCTGGCGCCGCTGGCCCATGAGCGCACCTGGCTCACGGTGACGGCCGAGCGTGCCGTAAGCCGCGCC
ATGGGGGGGAGCTGTTCCATGCCGCTGGCAGCACATGGCCAGTGGGACGGCGACACGCTCTCGCTGCGCGCCGCCTGGGG
CGACGTCGCGGCCCGGGTGCCGCTGGTACGCGCCGAGGGCGCGGCCCCCGTGCATACGCTGGAGCAGGCCGATGCGCTGG
GACTGGCCGTCGCCGCACAGCTGCGCACTGCGGGCGCGGTGGGAGCGCTCTGA

Protein sequence :
MTTPSPSLPSIVIATRESQLALWQAEHVQSLLRARGHAVALLGMTTRGDQILDRTLSKVGGKGLFVKELEVALEEGRADI
AVHSLKDVPMELPQGFALACVMEREDPRDAFVSPGYASLDELPHGAVVGTSSLRRQVLLQALRPDLQIEPLRGNVQTRLR
KLDEGQYAAIVLAAAGLKRLGLHERIRAVFTPEQMLPAAGQGALGIEIRGDRHDLREALAPLAHERTWLTVTAERAVSRA
MGGSCSMPLAAHGQWDGDTLSLRAAWGDVAARVPLVRAEGAAPVHTLEQADALGLAVAAQLRTAGAVGAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-60 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-60 52