Gene Information

Name : Dtpsy_2133 (Dtpsy_2133)
Accession : YP_002553586.1
Strain : Acidovorax ebreus TPSY
Genome accession: NC_011992
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 2280226 - 2281920 bp
Length : 1695 bp
Strand : +
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; Heavy metal transport/detoxification protein; KEGG: kpn:KPN_pK

DNA sequence : 
ATGAGCACTCTCAAAATCACCGGCATGACTTGCGACTCGTGCGCAGTGCATGTCAAGGACGCCCTGGAGAAAGTGCCCGG
CGTGCAATCAGCGGATGTCTCCTACGCCAAGGGCAGCGCCAAGCTCGCCATTGAGGTCGGCACGTCACCCGACGCGCTGA
CGGCCGCTGTAGCTGGACTCGGTTATCGGGCCACGCTGGCCGATGCCCCCTCAGTTTCGACGCCGGGCGGATTGCTCGAC
AAGATGCGCGATCTGCTGGGCAGAAACGACAAGACGGGTAGCAGCGGCGCATTGCATATCGCCGTCATCGGCAGCGGCGG
GGCCGCGATGGCAGCGGCGCTGAAGGCCGTCGAGCAAGGCGCACGTGTCACGCTGATCGAGCGCGGCACCATCGGCGGCA
CCTGCGTCAATGTCGGTTGTGTGCCGTCCAAGATCATGATCCGCGCCGCCCATATCGCCCATCTGCGCCGGGAAAGCCCG
TTCGATGGCGGCATCGCCGCTACCACGCCGACCATCCAGCGCACGGCGCTGCTGGCCCAGCAGCAGGCCCGCGTCGATGA
ACTGCGCCACGCCAAGTACGAAGGCATCTTGGAGGGCAATCCGGCGATCACTGTGCTGCACGGCTCCGCCCGCTTTAAGG
ACAATCGCAACCTGATCGTGCAACTCAACGACGGCGGCGAGCGCGTGGTGGCATTCGACCGCTGCCTGATCGCCACCGGC
GCGAGCCCGGCCGTGCCGCCGATTCCCGGCCTGAAAGACACTCCGTACTGGACTTCCACTGAAGCGCTGGTCAGCGAGAC
GATTCCTAAGCGCCTGGCCGTGATTGGCTCATCAGTGGTGGCGCTGGAGCTGGCGCAGGCGTTCGCCCGACTCGGAGCGA
AGGTGACGATCCTGGCTCGCAGCACGCTGTTCTTCCGCGAAGACCCAGCTATAGGCGAAGCCGTCACGGCCGCATTCCGC
ATGGAGGGCATCGAGGTGAGGGAACACACCCAGGCCAGCCAGGTCGCGTATATCAATGGTGAAGGGGACGGCGAATTCGT
GCTCACCACGGCGCACGGCGAACTGCGCGCCGACAAGCTGCTGGTCGCCACCGGCCGCGCGCCCAACACACGCAAGCTGG
CACTGGATGCGACGGGCGTCACGCTCACCCCGCAAGGCGCTATCGTCATCGACCCCGGCATGCGTACAAGCGTGGAACAC
ATCTACGCCGCAGGCGACTGCACCGACCAGCCGCAGTTCGTCTATGTGGCGGCAGCGGCCGGCACTCGCGCCGCGATCAA
CATGACCGGCGGTGACGCGGCCCTGAACCTGACCGCGATGCCGACCGTGGTGTTCACCGACCCGCAAGTGGCGACCGTAG
GCTACAGCGAGGCGGAAGCGCACCATGACGGCATCAAAACTGATAGTCGCACGCTAACGCTGGACAACGTGCCGCGCGCG
CTCGCCAACTTCGACACGCGCGGCTTCATCAAACTGGTGGTTGAAGAAGGCAGCGGACGACTGATCGGCGTGCAGGCAGT
GGCCCCGGAAGCGGGCGAACTGATCCAGACGGCCGCACTGGCGATTCGCAACCGGATGACGGTGCAGGAACTGGCCGACC
AGTTGTTCCCCTACCTGACGATGGTCGAAGGGTTGAAGCTCGCGGCGCAGACCTTCAACAAGGATGTGAAGCAGCTTTCC
TGCTGCGCCGGGTGA

Protein sequence : 
MSTLKITGMTCDSCAVHVKDALEKVPGVQSADVSYAKGSAKLAIEVGTSPDALTAAVAGLGYRATLADAPSVSTPGGLLD
KMRDLLGRNDKTGSSGALHIAVIGSGGAAMAAALKAVEQGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESP
FDGGIAATTPTIQRTALLAQQQARVDELRHAKYEGILEGNPAITVLHGSARFKDNRNLIVQLNDGGERVVAFDRCLIATG
ASPAVPPIPGLKDTPYWTSTEALVSETIPKRLAVIGSSVVALELAQAFARLGAKVTILARSTLFFREDPAIGEAVTAAFR
MEGIEVREHTQASQVAYINGEGDGEFVLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTPQGAIVIDPGMRTSVEH
IYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALNLTAMPTVVFTDPQVATVGYSEAEAHHDGIKTDSRTLTLDNVPRA
LANFDTRGFIKLVVEEGSGRLIGVQAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLS
CCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 99
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 99
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 99
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 92
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 92
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 92
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 85
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 85
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 79
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 76

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dtpsy_2133 YP_002553586.1 mercuric reductase BAC0652 Protein 0.0 86
Dtpsy_2133 YP_002553586.1 mercuric reductase BAC0653 Protein 0.0 80
Dtpsy_2133 YP_002553586.1 mercuric reductase BAC0650 Protein 6e-170 70