Gene Information

Name : Dtpsy_1863 (Dtpsy_1863)
Accession : YP_002553320.1
Strain : Acidovorax ebreus TPSY
Genome accession: NC_011992
Putative virulence/resistance : Unknown
Product : type I site-specific deoxyribonuclease, hsdr family
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 1985201 - 1987768 bp
Length : 2568 bp
Strand : +
Note : KEGG: pna:Pnap_4782 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases

DNA sequence :
ATGACTGAAGACCAACTGGAAAAGGAAACCCTGGGCTGGCTGGCTGATGTTGGCTACTCACTCCACAATGGGCTGGATAT
CGCCCAAGACGGCATCAACCCCCAGCGTGCCGATTACCGCCAAGTCGTCCTATCGTTTCGACTGCGTGAAGCCATCCAGC
GCCTGAATCCGCACATCCCGACGGCAGCCCGTGAAGACGCCCTGCACCGGGTGCTGGATTTGGGTATCCCGTCCCTGCTG
TCGGCCAACCGGGCCTTCCACAAGCTGCTGGTCGGTGGAGTGCCGGTGCAGTACCAGAAGGAAGGCGAAACCCGTGGTGA
CTTTGTTCGCTTGGTTGATTGGTCGGAGGCGTCGCGCAACGAGTTCTGGGCGGTCAATCAGTTCACCATCAAGGGGCCGC
ACCACACGCGCCGCCCCGACATCATCCTGTTCGTCAACGGCCTGCCGCTGGTCCTGCTGGAGCTAAAGAACCCTGCTGAC
CAGGCCGCCGACATCTGGAAAGCCTATGACCAGATTCAGACCTACAAGGAGCACATACCGGACGTATTCCAGTACAACGA
GGTGCTAGTCATCTCGGATGGCACCGAGGCGCGGCTCGGTTCCCTGTCAGCCAATGCCGAGCGCTTCATGCAATGGCGCA
CCATCGACGGCGTGAACCTGGACCCGCTGGGGGAGTTCAACGAGCTGGAAACGCTGGTGCGCGGTGCCCTGGCACCCCAG
TACCTGCTGGACTACCTGCGCTACTTCGTCCTGTTCGAAGACGACGGCAGCCTTGTTAAGAAAATTGCTGGCTACCACCA
GTTTCATGCTGTGCGCTCTGCCATCGCGCATGTGGTGGCCGCCTCCCGGCCCGACAGTGCTGCCAACCAGCGAGGGAAGG
GCGGGGTGGTGTGGCACACCCAAGGCAGCGGCAAGAGCATCACCATGACATGCTTTGCCGCCCGGGTGATGCAGGAGCCC
GCGATGGCCAATCCCACCATCGTCGTCATCACCGACCGCAACGACCTGGACGGGCAACTGTTTGGAGTGTTCAGCCTGGC
GCAAGACCTGCTGCGCGAGCAGCCCGCCCAGGCCAGCACCCGGCAGCAATTGCGGCAACTGCTTAGCAACCGGCCCTCGG
GCGGCATTGTGTTTGCCACCATCCAGAAGTTCATGCCGGGCGAGGATGAGGACATGTTCCCTGTGCTCTCAGAGCGCCAC
AACATCGTGGTGATTGCTGACGAAGCCCACCGCACCCAGTACGGCTTCGAGGCCAAACTCAAGACCATCAAGAACAAGGG
TGCCAGTGCCGCCAAGGCGCTGGTCCTGGCCGACGGCGAGACCTCGGGAGCAGCCGTTACCGCCGACTTTGCGGAGCCGG
AGTACCTGACGAAGTACCAGGTTGGCTATGCCCAGCACCTGCGCGATGCCTTGCCACACGCCACCTTCGTGGCCTTTACC
GGCACGCCCGTCAGCAGTACCGACCGCGACACCCGTGCTGTTTTTGGTGACTACATCTCGGTCTACGACATGCAGCAGGC
CAAAGAAGACGGGGCCACGGTCGCCATCTATTACGAAAGCCGGCTGGCCAAGCTTCGACTCAAGGAAGAGGACCTGTCCT
TTCTTGATGATGAAGTTGACGAGTTGGCCGAGGACGAAGAAGAAAGTACCCAGGCGCAACTCAAAAGCCGCTGGGCTGCG
CTGGAAAAGGTGGTGGGCGCCACGCCCCGCGTGGCCAGCGTGGCCGCTGACCTGGTGGCGCACTTCGAGGAGCGCAACAA
GACCCAGGACGGCAAGGCCATGGTGGTCGCCATGAGCCGGGACATCTGCGTGCACCTGTACAACGAAATCGTGAAGCTAC
GTCCCGACTGGCACGACAGCGACCCAGAAAAAGGTGCCATCAAGATTGTGATGACTGGTAGCGCCAGCGACAAAGCCTTG
CTGCGCCCCCACATCTACAGCGCCCAGGTCAAGAAACGCCTGGAAAAACGTTTCAAAGACCCCACGGACCCGTTGCGCCT
GGTCATCGTGCGCGATATGTGGCTCACCGGCTTCGATGCCCCTTGCGTTCACACCATGTATGTGGACAAGCCCATGAAGG
GGCACAACCTGATGCAGGCGATTGCCCGCGTCAACCGTGTTTTCAAGGACAAGCAGGGCGGCCTGGTCGTGGACTATATC
GGCATCGGCAATGAACTGAAGGCCGCCATGAAGGAGTACACCGCCAGCCAAGGCCGCGGCAAGCCTACCGTGGATGCCCA
CGAGGCCCTGTCGGTGCTACTGGAGAAGATGGACGTGCTGCGCGCCATGCTGCACGGGTATGACTACTCAGGCTTCCTCA
CAGGTGGCCACAAGACCCTGGCGGGTGCAGCCAACCACGTTCTGGGCATCAAGTCCGAGGGCAAGGACAGCAAGCGTGAC
GGCAAAAAGCGCTTTGCTGACAGTGCGCTGGCCATGAGCAAGGCCTTCAGCCTGTGCTGCACCCTGGACGAAGCCAAGGC
CCTACGCGAGGAGGTGCCAGCACGCGACTCTTCAAAGGCGTGCTTCCAGGTGCAAGCTGTCCTGAACTGTGGGCGCTTGA
AACTGTGA

Protein sequence :
MTEDQLEKETLGWLADVGYSLHNGLDIAQDGINPQRADYRQVVLSFRLREAIQRLNPHIPTAAREDALHRVLDLGIPSLL
SANRAFHKLLVGGVPVQYQKEGETRGDFVRLVDWSEASRNEFWAVNQFTIKGPHHTRRPDIILFVNGLPLVLLELKNPAD
QAADIWKAYDQIQTYKEHIPDVFQYNEVLVISDGTEARLGSLSANAERFMQWRTIDGVNLDPLGEFNELETLVRGALAPQ
YLLDYLRYFVLFEDDGSLVKKIAGYHQFHAVRSAIAHVVAASRPDSAANQRGKGGVVWHTQGSGKSITMTCFAARVMQEP
AMANPTIVVITDRNDLDGQLFGVFSLAQDLLREQPAQASTRQQLRQLLSNRPSGGIVFATIQKFMPGEDEDMFPVLSERH
NIVVIADEAHRTQYGFEAKLKTIKNKGASAAKALVLADGETSGAAVTADFAEPEYLTKYQVGYAQHLRDALPHATFVAFT
GTPVSSTDRDTRAVFGDYISVYDMQQAKEDGATVAIYYESRLAKLRLKEEDLSFLDDEVDELAEDEEESTQAQLKSRWAA
LEKVVGATPRVASVAADLVAHFEERNKTQDGKAMVVAMSRDICVHLYNEIVKLRPDWHDSDPEKGAIKIVMTGSASDKAL
LRPHIYSAQVKKRLEKRFKDPTDPLRLVIVRDMWLTGFDAPCVHTMYVDKPMKGHNLMQAIARVNRVFKDKQGGLVVDYI
GIGNELKAAMKEYTASQGRGKPTVDAHEALSVLLEKMDVLRAMLHGYDYSGFLTGGHKTLAGAANHVLGIKSEGKDSKRD
GKKRFADSALAMSKAFSLCCTLDEAKALREEVPARDSSKACFQVQAVLNCGRLKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 54
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 46
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 46
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 46