Gene Information

Name : guaA (Dtpsy_1261)
Accession : YP_002552728.1
Strain : Acidovorax ebreus TPSY
Genome accession: NC_011992
Putative virulence/resistance : Unknown
Product : gmp synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1323293 - 1324909 bp
Length : 1617 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAACACGACAAGATCCTCATCCTCGACTTCGGCTCCCAGGTCACCCAACTCATCGCGCGCCGCGTGCGCGAGACGCA
TGTCTACTGCGAGGTCCACCCCTGCGACGTGAGCAGCGACTGGGTGCGCCAGTTCGCCGCAGACGGCAAGCTCAAGGGTG
TGATCCTGTCGGGCAGCCACGCCAGCGTCTACGAAGTGGACGACCGCGCCCCTGACGCCGTGTTCGAGTTGGGCGTGCCC
GTGCTGGGCATCTGCTACGGCATGCAGACCATGGCCGCGCAGCTGGGCGGCAAGGTCGAGGGCTCGCACAGCCGCGAGTT
CGGCTATGCCGAAGTCCGCGCCCATGGCCATACCGCGCTGCTCAAGGGCATCGAGGATTTCTCCACGCCCGAGGGCCACG
GCATGCTGAAGGTGTGGATGAGCCACGGCGACAAGGTCACCGAGCTGCCTCCCGGTTTCAAGCTGATGTGCTCCACCGGC
AACTGCCCCATCGCCGGCATGGCGGACGAAATGCGGCGCTTCTACGCCGTGCAATTCCACCCCGAGGTCACGCACACGGT
GCAGGGCGCGGCGCTGCTAAACCGCTTTGTGCGCGAGATCTGTGGCGCCCAGGCGGACTGGATCATGCGCGACCACATCG
AGGAAGCCGTGCAGAAGATCCGCGAGCAGGTGGGCGGCGAGGAAGTGATCCTAGGCCTGTCTGGCGGCGTGGATTCGTCG
GTGGCTGCGGCCCTGATCCACCGTGCGATTGGCGACCAGCTCACTTGCGTGTTCGTGGACCACGGCCTGCTGCGCCTCAA
CGAAGGCGATATGGTCATGGACATGTTCGCAGGCAAGCTGCACGCGAAGGTGGTGCGCGTGGATGCCTCGGACCTGTTCC
TGGGTGAGCTGGCCGGTGTGTCGGAGCCCGAGCAAAAGCGCAAGATCATCGGCCGATTGTTCGTGGACGTGTTCAAGGCC
GAAGCCGAAAAGCTCAAGGCCAGCGGCCAGGGCCACAAGGGCGCGACCTTCCTGGCGCAAGGCACCATCTACCCCGACGT
GATCGAGTCCGGCGGTGCCAAGAGCAAGAAGGCTGTCACCATCAAGAGCCACCACAACGTGGGCGGGCTGCCCGAGCAAC
TCGGCCTCAAACTGCTGGAGCCGCTGCGCGACCTGTTCAAGGACGAGGTGCGCGAGCTCGGCGTGGCCCTGGGGCTGCCG
CGCGAAATGGTCTACCGCCATCCGTTCCCCGGCCCGGGCCTGGGCGTGCGCATTCTGGGCGAGGTGAAGAAGGAATACGC
CGACCTGCTGCGCCGCGCCGATGCCATCTTCATCGAAGAGCTGCGCAACTTCACCGACGAAGCCACGGGCAAGACCTGGT
ACGACCTCACCAGCCAGGCCTTCACCGTGTTCCTGCCCGTCAAGAGCGTGGGCGTGATGGGCGATGGCCGCACCTACGAC
TATGTGGTGGCACTGCGCGCGGTGCAGACCAGCGACTTCATGACAGCCGACTGGGCGGAGTTGCCCTACGCGCTGTTGAA
GAAGGTCTCCAGCCGCATCATCAATGAGGTGCGCGGCATCAACCGCGTGACCTACGACGTGTCGAGCAAGCCGCCTGCCA
CCATCGAGTGGGAGTGA

Protein sequence :
MQHDKILILDFGSQVTQLIARRVRETHVYCEVHPCDVSSDWVRQFAADGKLKGVILSGSHASVYEVDDRAPDAVFELGVP
VLGICYGMQTMAAQLGGKVEGSHSREFGYAEVRAHGHTALLKGIEDFSTPEGHGMLKVWMSHGDKVTELPPGFKLMCSTG
NCPIAGMADEMRRFYAVQFHPEVTHTVQGAALLNRFVREICGAQADWIMRDHIEEAVQKIREQVGGEEVILGLSGGVDSS
VAAALIHRAIGDQLTCVFVDHGLLRLNEGDMVMDMFAGKLHAKVVRVDASDLFLGELAGVSEPEQKRKIIGRLFVDVFKA
EAEKLKASGQGHKGATFLAQGTIYPDVIESGGAKSKKAVTIKSHHNVGGLPEQLGLKLLEPLRDLFKDEVRELGVALGLP
REMVYRHPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELRNFTDEATGKTWYDLTSQAFTVFLPVKSVGVMGDGRTYD
YVVALRAVQTSDFMTADWAELPYALLKKVSSRIINEVRGINRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-124 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-124 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-124 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-110 48