Gene Information

Name : guaA (Avi_0327)
Accession : YP_002548219.1
Strain :
Genome accession: NC_011989
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 281180 - 282742 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGACAGCACATCCCGACAGCGTTCTCATCATCGATTTCGGCAGCCAGGTAACGCAGCTGATTGCGCGGCGCGT
TCGTGAAACCGGCGTGTACTGCGAAATCGTCCCTTTCCAGTCATCCGAAGAGGGCTTCGCACGGTTGAAGCCAAAAGCGG
TTATACTGTCTGGAAGCCCCGCCTCGGCACTGGATGAAGGCAGCCCCCGCGTTCCCCAGGTGATTTTCGACAGCGGCCTG
CCAATCTTTGGCATCTGCTATGGCCAGCAAACCATCTGCGCCCAGCTGGGTGGCAAGGTGGAAGCCGGGCATCACCGCGA
ATTTGGTCGCGCCTTCCTTGAGATCGAGCAGGATTGCAAGCTATTCGAAGGTCTCTGGTCGGTTGGTTCACGCCATCAGG
TCTGGATGTCGCATGGCGACCGCGTCACCGCGATCCCGCCAGGCTTTCGGGTTCTGGCCACCTCCTCCAATGCGCCTTTC
GCCTTCATTGCCGATGAGGCCCGCAAATATTACGCCGTGCAGTTCCACCCGGAAGTGGTGCATACGCCTGACGGTGCCAA
GCTGATCCAGAATTTCGTCCATAATATCGCTGGCATTACTGGCGACTGGAGCATGTCGGCCTACCGCGCCAAAGCCGTGG
AACAGATCCGCGCCCAGGTCGGTGACAAGCGGGTGATCTGCGCCTTGTCCGGCGGCGTCGATAGTTCGGTCGCAGCCCTG
CTGATCCATGAGGCGGTCGGCGACCAGCTGACCTGCATCCTGGTTGACCACGGGTTGATGCGTAAGAACGAGGCGGCGGA
TGTCGTTGCCATGTTCAAGGAACATTACAATCTGCATCTGATCCATGTCGATGCCATCGACCGCTTCGTCGGCGAGCTGG
AAGGCGTGTCCGACCCGGAAACCAAGCGCAAGATCATTGGTCGCCTGTTCATCGAAACCTTCGAGGAAGAAGCCAAGAAG
CTTGGTGGCGCAGACTTCCTCGGCCAGGGCACGCTCTATCCTGACGTCATCGAAAGCGTCTCCTTCTCCGGCGGCCCGTC
TGTCACCATCAAGAGCCACCACAATGTCGGCGGCCTGCCAGACCGCATGAACATGAAGCTGGTGGAACCGCTGCGCGAGC
TGTTCAAGGACGAAGTGCGCGTTCTCGGCAAGGAGCTTGGCCTGCCCGACTCATTCATTGGCCGGCACCCCTTCCCCGGC
CCCGGCCTTGCCATTCGCTGCCCCGGCGGCGTGACCCGCGAAAAGCTCGATATCCTGCGCGAAGCCGATGCCATCTATCT
GGACGAAATCCGCAAGGCCGGTCTTTACGATGCTATCTGGCAGGCCTTCGCCGTGCTGCTGCCGGTCCAGACTGTCGGCG
TGATGGGCGATGGCCGTACCTATGAATTCGTCTGCGCACTGCGCGCCGTCACCTCCGTTGATGGCATGACCGCGGATTTC
TACCACTATGACATGGAATTCCTCGGCCGTGCCGCTACCCGCATCATCAACGAAGTCCGCGGCATCAACCGGGTCGTCTA
TGATGTAACATCCAAGCCGCCCGGCACCATCGAGTGGGAATGA

Protein sequence :
MTQTAHPDSVLIIDFGSQVTQLIARRVRETGVYCEIVPFQSSEEGFARLKPKAVILSGSPASALDEGSPRVPQVIFDSGL
PIFGICYGQQTICAQLGGKVEAGHHREFGRAFLEIEQDCKLFEGLWSVGSRHQVWMSHGDRVTAIPPGFRVLATSSNAPF
AFIADEARKYYAVQFHPEVVHTPDGAKLIQNFVHNIAGITGDWSMSAYRAKAVEQIRAQVGDKRVICALSGGVDSSVAAL
LIHEAVGDQLTCILVDHGLMRKNEAADVVAMFKEHYNLHLIHVDAIDRFVGELEGVSDPETKRKIIGRLFIETFEEEAKK
LGGADFLGQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPDRMNMKLVEPLRELFKDEVRVLGKELGLPDSFIGRHPFPG
PGLAIRCPGGVTREKLDILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-134 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-134 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-134 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-114 48