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Name : ddl (Arad_1819) Accession : YP_002544086.1 Strain : Genome accession: NC_011985 Putative virulence/resistance : Resistance Product : D-alanyl-alanine synthetase A Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : - Position : 1436749 - 1437816 bp Length : 1068 bp Strand : + Note : D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli DNA sequence : ATGACCTCAAGATTGCGCGTAGCGGTCCTCTTCGGCGGACAGTCCTCTGAACACGATGTTTCCCTCATGTCCGCCCGCAA CGTCATTAAAGCAATCGATGTCGACAAATACGAGATCGTGCCGATTGTCATCCGCCGCGATGGACAGTGGCTGCTGACCG CTTTGGAAGGGGGAGCGCTGCCGGACCCGGTCGTTTATGCGGGGAGCGAAGTTTGCCTGCTGCCGGGTGGTAAGGGCCGG ATTCTCGCTGTCGGCGACCCGACCGGACCGCGCGAGCTGCCGGCGATAGACATCCTGTTCCCGGTTCTGCACGGTCTCTA TGGCGAGGATGGCTCCATCCAGGGCCTCGCCCGAATGGTCGGCGTTCCGTTGGTCGGCTGCGGCATCCTGGGATCGGCAA CCGCCATCGACAAGGATATCGCCAAGCGCCTGCTGCGCGACGCCGGCCTGCCGGTCGCCCGTTCGATCACCGTGAGACCT GGCGATACTCTATCGTTTGAGGAGGCAGCGAGTGCCTTGGGCTCGCCCGTTTTCGTCAAGCCGGTGCGACAGGGCTCTTC CGTCGGCGTCAGCAAGGCGGCGAACGCCGAGGAATTTCGCGCGGCGCTCATCGAGGCGTTCAAGCATGACGACAAGGTGC TCATAGAAGAGTTCGTCAAGGCGCGCGAAATCGAATGCGCCGTCCTGGAGCAGACCGATGGCACGCTGTTCGTTTCCCTG CCCGGCGAGATCGTCACCGGCCAGGACCACAGCTTCTATACCTATGACGCAAAGTATATCGATGAGGATGGCGCCATAAC CAGCGTTCCGGCACAATTGCCTGCCGATCTCACCCAGCATCTCCGCGAGCTCTCGCTGGACGCGTTTCGCGCATTGGGCT GCGAAGGTCTCGCGCGCGTCGATTTCTTCGTGAGGCCGGACATGAGCATGGTGGTGAACGAGGTCAATACGATGCCGGGC TTCACCAATATCAGCATGTACCCGAAGGCCATGGAAGCGACGGGGATTTCCTATCCGGCGCTCGTCGACCGGCTAATCGA ACACGGGCTTGCAAGAGGCGGTCGATAG Protein sequence : MTSRLRVAVLFGGQSSEHDVSLMSARNVIKAIDVDKYEIVPIVIRRDGQWLLTALEGGALPDPVVYAGSEVCLLPGGKGR ILAVGDPTGPRELPAIDILFPVLHGLYGEDGSIQGLARMVGVPLVGCGILGSATAIDKDIAKRLLRDAGLPVARSITVRP GDTLSFEEAASALGSPVFVKPVRQGSSVGVSKAANAEEFRAALIEAFKHDDKVLIEEFVKAREIECAVLEQTDGTLFVSL PGEIVTGQDHSFYTYDAKYIDEDGAITSVPAQLPADLTQHLRELSLDAFRALGCEGLARVDFFVRPDMSMVVNEVNTMPG FTNISMYPKAMEATGISYPALVDRLIEHGLARGGR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 2e-49 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ddl | YP_002544086.1 | D-alanyl-alanine synthetase A | AY145441.gene.p01 | Protein | 1e-48 | 41 |
| ddl | YP_002544086.1 | D-alanyl-alanine synthetase A | AF310956.2.orf5.gene | Protein | 5e-49 | 41 |
| ddl | YP_002544086.1 | D-alanyl-alanine synthetase A | AF130997.1.orf4.gene | Protein | 3e-54 | 41 |
