Gene Information

Name : Geob_2272 (Geob_2272)
Accession : YP_002537727.1
Strain : Geobacter daltonii FRC-32
Genome accession: NC_011979
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2518806 - 2519567 bp
Length : 762 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAAGATAACTGCAATTATCCCCGCAAGATATGCTTCGACCCGTTTCGAAGGGAAAGCCCTGGCTCAGATTCAGGGAAA
GCCCATGGTGCAGCATGTTTACGAACGTACCCTGAAGGCATCGCTGGTCTCGGAAGTTATCGTGGCCACCGACGATGAGC
GTATCGTTGCGGCTGTTCGTGCTTTCGGCGGCAGAGCGGAAATGACCTCCAGGTCCCATGAGACCGGCACCGACCGCCTG
GCTGAGGTGGCTGCCCGGCTCGATTCGGACATTATCGTCAATGTACAGGGAGACGAACCCCTCATAGATCCGGCAATGAT
CGATGAGGCCATCAGTCCCCTTGCCGAGGACTCTTCCCTGCTCATGGGAACACTCAAGACACGCATCAAGAGCCTGCATG
ACTTTCTCAGTCCCAACGTGGTCAAGGTTGTAACCGATTGGGAGGGGTATGCCCTCTATTTTTCCCGTTCGCCGCTGCCG
AACTTTCGCGACAAATGGAATGATCTGAAGGACGAGGCGTTCTCCTCACGTAAGCTGCTCTGCTTCAAACATGTGGGGCT
GTACGTCTACAGGCGCGAGTTCCTTCTTCAGTTCGCCCAGATGTCACCCACCTATCTTGAGATGGCGGAAAAACTGGAAC
AGCTCAGGGTTTTGGAGAATGGTTATCGCATCAAGGTGGTCGAGACCGATTTTGAATCGATCGGTGTCGATACACCTGGT
GACCTGGATAAGGTGCTGGAAAGGTTGAAGGACCGGGGATAA

Protein sequence : 
MKITAIIPARYASTRFEGKALAQIQGKPMVQHVYERTLKASLVSEVIVATDDERIVAAVRAFGGRAEMTSRSHETGTDRL
AEVAARLDSDIIVNVQGDEPLIDPAMIDEAISPLAEDSSLLMGTLKTRIKSLHDFLSPNVVKVVTDWEGYALYFSRSPLP
NFRDKWNDLKDEAFSSRKLLCFKHVGLYVYRREFLLQFAQMSPTYLEMAEKLEQLRVLENGYRIKVVETDFESIGVDTPG
DLDKVLERLKDRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-43 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-44 46
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 8e-44 46